Alex Shared "Pharm5" - 48 Picmonics
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Pharm5
Peptic Ulcer Disease Interventions
- Combination Drug Therapy
- Two Antibiotics
- Proton Pump Inhibitor (PPI)
- Decrease Acid Secretion
- Avoid NSAIDs
- Diet and Lifestyle Changes
1 min
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- Mechanism
- H2 Receptor Blocker
- Indications
- Suppress Gastric Acid Secretion
- Side Effects (All)
- Pneumonia
- Side Effects - Cimetidine
- Anti-androgen Effects
- CNS Changes
2 mins
H2 Receptor Blocker Side Effects
- Side Effects
- Decrease Creatinine Clearance
- Cimetidine
- Crosses Blood-Brain Barrier
- Anti-Androgen
- Inhibits Cytochrome P450
1 min
H2 Receptor Blocker
- "-tidine" Suffix
- Indications
- Gastroesophageal Reflux Disease (GERD)
- Peptic Ulcer
- Mechanism
- Block Histamine H2 Receptors
- Parietal Cells
52 secs
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
Sucralfate (Carafate)
- Mechanism
- Creates Protective Barrier
- Indications
- GI Ulcers
- Side Effects
- Constipation
- Considerations
- Require Acidic Environment
- Give on Empty Stomach
- Oral Suspension Available
- May Decrease Absorption of Other Meds
2 mins
Dinoprostone and Misoprostol
- Mechanism
- Prostaglandins
- Indications
- Promote Cervical Ripening
- Prevent GI Ulcers
- Medical Abortion
- Side Effects
- Fetal Distress
- Hyperstimulation of Uterus
- Considerations
- Vaginal Insertion
- Give Before Induction of Labor
2 mins
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Complications
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
2 mins
TNF-Alpha Inhibitors Overview
- Mechanism
- Downregulates Pro-inflammatory Cytokines
- Decreased Lymphocyte Activation and Migration
- Granuloma Breakdown
- Treats
- Crohn's Disease
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
- Psoriasis
- Ankylosing Spondylitis
1 min
Class IA Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Arrhythmias
- Mechanism of Action
- Increase AP, ERP, and QT interval.
- Drugs
- Disopyramide
- Procainamide
- Drug-induced Lupus
- Quinidine
- Cinchonism
- Shared Side Effects
- Thrombocytopenia
- Torsades de Pointes
1 min
Class IC Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Used as Last Resort
- V-Tach
- Mechanism of Action
- No Effect on AP Duration
- Drugs
- Propafenone
- Flecainide
- Contraindications
- Post-Myocardial Infarction
56 secs
Class IB Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Arrhythmias
- After Myocardial Infarction
- Mechanism of Action
- Affect Ischemic Tissue
- Decrease AP duration
- Drugs
- Mexiletine
- GI Upset
- Lidocaine
- CNS Depression
- Tocainide
- Phenytoin
- Hirsutism
2 mins
Class I Antiarrhythmics (Na+ Channel Blockers) Overview
- Indications
- Arrhythmias
- Local Anesthesia
- Mechanism of Action
- Block or Slow Conduction
- Block Na+ Channels
- Raise Threshold
- State Dependent
- Contraindication
- Hyperkalemia
1 min
Lidocaine
- Mechanism
- Blocks Na+ Channels
- Indications
- Ventricular Arrhythmia
- Anesthetic
- Side Effects
- Paresthesias
- Seizures
- Respiratory Depression
- Drowsiness
- Consideration
- Anesthetic Effects Extended with Epinephrine
1 min
Class III Antiarrhythmics (K+ Channel Blockers)
- Indications
- Arrhythmias
- Mechanism of Action
- Increase AP Duration, ERP, and QT Interval
- Drug Names
- Amiodarone
- Check Function Tests
- Dirty Drug
- Ibutilide
- Dofetilide
- Sotalol
- Beta-Blocker
2 mins
Class IV Antiarrhythmics (Ca2+ Channel Blockers)
- Indications
- SVT
- Subarachnoid Hemorrhage
- Mechanism of Action
- Decrease Conduction Velocity
- Increase PR Interval and ERP
- Drugs
- Verapamil
- Diltiazem
- Nimodipine
- Side Effects
- Cardiovascular
- Constipation
2 mins
Adenosine (Adenocard)
- Mechanism
- Slows AV Conduction
- Indications
- Supraventricular Tachycardia (Paroxysmal)
- Side Effects
- Bradycardia
- Flushing
- Dyspnea
- Considerations
- Rapid IV Push
- Caffeine and Theophylline Decrease Effectiveness
- Dipyridamole May Intensify Effects
2 mins
Digoxin Mechanism and Indication
- Direct inhibition of Na K ATPase
- Indirect inhibition of Na Ca exchanger
- Increase Ca in cell
- Positive Inotropy
- CHF
- Stimulates Vagus Nerve
- Decreased conduction at AV node
- Atrial Fibrillation
1 min
ACE Inhibitors
- -Pril Suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Inhibits ACE
- Decreases GFR
- Inhibits Constriction of Efferent Arteriole
- Side Effect
- Increased Bradykinin
- Cough
1 min
