Shannon Shared "pharm test 6" - 22 Picmonics

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pharm test 6

Isoniazid (INH)
Mechanism
Interferes with DNA Metabolism
Indications
Tuberculosis (TB)
Side Effects
Optic Neuritis
Nausea and Vomiting
Hepatotoxicity
Peripheral Neuropathy
Considerations
Vitamin B6 Prophylaxis
Monitor AST/ALT
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2 mins
Ethambutol (Myambutol)
Mechanisms
Inhibits RNA Synthesis
Bacteriostatic
Indications
Tuberculosis (TB)
Side Effects
Optic Neuritis
Red/Green Color Blindness
Gouty Arthritis
Consideration
Monitor Vision Acuity
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2 mins
Fluoroquinolones
End in "-floxacin"
Mechanism of Action
Bactericidal
Indications
Variety of Infections
Side Effects
GI Distress
Photosensitivity
Achilles Tendon Rupture
Contraindications
Pregnancy
Children
Myasthenia Gravis
Considerations
Avoid Milk Products or Antacids
Slow IV Infusion
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2 mins
Fluoroquinolones Toxicities
Diarrhea
Skin Rash
Headache
Tendon Rupture in Adults
Myalgias in Kids
Damage to Cartilage
Teratogen
QT Prolongation
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1 min
Nitrofurantoin (Macrodantin)
bacterial enzymes that regulate carb metabolism
Hepatotoxicity
UTI
eat with food
check liver functioning tests
assess LFT, UTI, and ECG
Nausea and Vomiting
disrupts cell wall synthesis
blood disorders
Contraindication
Contraindications
Contraindication
renal and liver failure
check skin
check skin
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Metronidazole (Flagyl)
Seizures
gynecological infections
gynecological
Stevens-Johnson Syndrome
No Alcohol Interaction
assess skin
CNS Changes
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Sulfonamides
Mechanism of Action
Bacteriostatic
Indications
Urinary Tract Infection
Side Effects
Crystalluria
Photosensitivity
Hemolytic Anemia
Kernicterus
Rash
Considerations
Sulfa Allergy
Encourage Fluids
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2 mins
Macrolides
End in "-thromycin"
Mechanism of Action
Bacteriostatic
Indications
Alternative for Penicillin Allergy
Respiratory Infections
Pneumonia
Side Effects
QT Prolongation and Sudden Death
C.Diff Overgrowth
GI Distress
Considerations
Slow IV Infusion
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2 mins
Macrolides Side Effects
Side Effects
Diarrhea
Prolonged QT Interval
P450 Inhibitor
Cholestatic Hepatitis
Skin Rash
Eosinophilia
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2 mins
Aminoglycoside Overview
End in "-mycin"
GNATS
Gentamicin
Neomycin
Amikacin
Tobramycin
Streptomycin
Mechanism of Action
Bactericidal
Indications
Severe Gram Negative Infections
Bowel Surgery Prep
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1 min
Aminoglycoside Side Effects
Side Effects
Ototoxicity
Nephrotoxicity
Respiratory Paralysis
Contraindications
Pregnancy
Considerations
Peak and Trough
Never Mix with Penicillin in Same IV
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2 mins
Clindamycin
Mechanism
Bacteriostatic
Binds 50S Ribosomal Subunit
Indications
Gram-Positive Infections
Anaerobic Infections
Side Effects
Rash
Pseudomembranous Colitis
C. Difficile (Associated Diarrhea)
Arrhythmias
Blood Dyscrasias
Considerations
Monitor for Diarrhea
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3 mins
Linezolid (Zyvox)
Mechanism Of Action
Oxazolidinone Antibiotic
Binds 23S rRNA of 50S Subunit
Inhibits Protein Synthesis
Indication
Gram-Positive Organisms
MRSA
VRE (Vancomycin Resistant Enterococci)
Side Effects
Bone Marrow Suppression
Decreased Platelet Count
Peripheral Neuropathy
Lactic Acidosis
Serotonin Syndrome
Considerations & Patient Education
Avoid Tyramine Containing Foods
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4 mins
Penicillin
Mechanism of Action
Weakens Cell Wall
Indications
Gram-Positive Infections
Prophylaxis
Side Effects
Pain at IM Injection Site
Allergic Reaction
Considerations
Skin Tests
Allergy ID
Medication Education
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2 mins
Cephalosporins
Starts with "Cef-"
Mechanism of Action
Bactericidal
Indications
Gram-Positive and Gram-Negative Infections
Side Effects
Allergic Reactions
Thrombophlebitis
Bleeding
Contraindications
Renal Impairment
Considerations
Avoid IV Calcium with Ceftriaxone
No Alcohol
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2 mins
Imipenem and Meropenem (Carbapenems)
Mechanism
Carbapenems
Broad-spectrum Antibiotic
Bactericidal
Indications
Gram Positive and Gram Negative Infections
Side Effects
GI Distress
Suprainfections
Seizures
Considerations
Penicillin Allergy
IV or IM Route
Imipenem Combined with Cilastatin
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3 mins
Aztreonam (Azactam)
Mechanism
Monobactam Antibiotic
Bactericidal
Indications
Gram-Negative Infections
No Activity on Gram-Positives or Anaerobes
Side Effects
Blood Dyscrasias
Pain at Injection Site
Considerations
Safe for Penicillin Allergy
Synergistic with Aminoglycosides
Nebulizer Form Available
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2 mins
Vancomycin
Mechanism of Action
Inhibits Bacterial Cell Wall Synthesis
Indications
Serious Gram-Positive Infections
Side Effects
Nephrotoxicity
Ototoxicity
Red Man Syndrome
Thrombophlebitis
Nursing Considerations
Culture Samples First
Infuse IV Over 60 Minutes
Take Around the Clock
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2 mins
Vancomycin Side Effects & Toxicity
Side Effects
Thrombophlebitis
Nephrotoxicity
Ototoxicity
Diffuse Flushing Called Red Man Syndrome
Prevent with Antihistamine
Prevent with Slow Infusion
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2 mins
Tetracyclines Overview
End in "-cycline"
Mechanism of Action
Bacteriostatic
Indications
Infectious Diseases
Acne
Periodontal Disease
Nursing Considerations
Avoid Milk, Antacids, Iron
Sunlight Protection
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1 min

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