Ivan Shared "Pharm" - 216 Picmonics

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Pharm

Hydrochlorothiazide HCTZ
Mechanism of Action
Inhibits Reabsorption NaCl and H2O
Indications
Edema
Mild to Moderate Hypertension
Side Effects
Hypokalemia
Hyponatremia
Dehydration
Hyperglycemia
Gout
Contraindications
Sulfa Allergy
Pregnancy and Breastfeeding
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Zanamivir (Relenza) and Oseltamivir (Tamiflu)
Indications
Influenza A and B
Treatment and Prophylaxis
Mechanism
Inhibits Release of New Virus
Inhibits Influenza Neuraminidase
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1 min
Hypertension Medications
Diuretics
Beta Blockers
Angiotensin Receptor Blockers (ARBs)
Calcium Channel Blockers
ACE Inhibitors
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1 min
1st Generation Cephalosporin
Drug Names
Cefazolin
Cephalexin
Indications (PEcK Mnemonic)
Proteus mirabilis
E. coli
Klebsiella
Gram-Positive Cocci
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1 min
Ibuprofen (Advil, Motrin)
Mechanisms
NSAID
COX Inhibitor
Indications
General Pain
Fever
Inflammatory Conditions
Side Effects
GI Ulcers
Nephrotoxicity
Rash
Considerations
Avoid with Alcohol
Risk of Thrombotic Event
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2 mins
3rd Generation Cephalosporin
Drug Names
Cefotaxime
Ceftriaxone
Cefdinir
Ceftazidime
Pseudomonas
Indications
Serious Gram-Negative Bacteria Resistant to Other Beta-Lactams
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1 min
Imatinib (Gleevec)
Indications
Chronic Myelogenous Leukemia (CML)
Inhibitor of BCR-ABL Tyrosine Kinase
Caused by Philadelphia Chromosome
GI Stromal Tumors
Inhibitor of C-kit Tyrosine Kinase
Toxicity
Fluid Retention
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1 min
5th Generation Cephalosporin
Mechanism
Beta-Lactam
Indications
Resistant Bacteria
Broad Spectrum Gram-Positive and Gram-Negative
Drugs
Ceftobiprole
Has Pseudomonas Coverage
Ceftaroline
No Pseudomonas Coverage
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1 min
Imipenem
Mechanism
Resistant to beta lactamases
Broad Spectrum
Indications
Anaerobes
Gram-Negative Rods
Gram-Positive Cocci
Must administer with cilastatin
Cilastatin is inhibitor of renal dehydropeptidase I
Side Effects
Diarrhea
Skin rash
Seizures
Considerations
Meropenem
Stable to dehydropeptidase I
Reduced risk of seizures (Non seizure causing)
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ACE Inhibitors
-Pril Suffix
Indications
Hypertension
CHF
Diabetic Nephropathy
Mechanism of Action
Inhibits ACE
Decreases GFR
Inhibits Constriction of Efferent Arteriole
Side Effect
Increased Bradykinin
Cough
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1 min
Indirect Cholinomimetics
Acetylcholinesterase Inhibitors
Doesn't Cross BBB
Edrophonium
Myasthenia Gravis (Diagnosis)
Pyridostigmine and Neostigmine
Myasthenia Gravis (Tx)
Ileus
Crosses BBB
Physostigmine
Atropine Overdose
Glaucoma
Donepezil
Alzheimer's
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Acetaminophen Antidote
Antidote
N-Acetylcysteine
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Inhaled Anesthetics
Mechanism of Action
Unknown Mechanism
Inhaled Anesthetic Drugs
HEISMN Drug Name Acronym
Side Effects
Respiratory Depression
Myocardial Depression
Lower Metabolic Demand, Increased Cerebral Blood Flow
Hepatotoxicity (Halothane)
Nephrotoxicity (Methoxyflurane)
Seizure (Enflurane)
Malignant Hyperthermia
Expansion of Trapped Gas
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2 mins
Acetylcholinesterase Inhibitor Poisoning
DUMBBELSS
Diarrhea
Urination
Miosis
Bronchospasm
Bradycardia
Emesis
Lacrimation
Salivation
Sweating
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2 mins
Integrase Inhibitors
-gravir Suffix
Indications
HIV
Mechanism
Blocks Insertion of Viral Genome
Inhibit Actions of Integrase
Side Effects
Hypercholesterolemia
Increased LFT's
Insomnia
Increased Creatine Kinase (CK)
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1 min
Adenosine (Adenocard)
Mechanism
Slows AV Conduction
Indications
Supraventricular Tachycardia (Paroxysmal)
Side Effects
Bradycardia
Flushing
Dyspnea
Considerations
Rapid IV Push
Caffeine and Theophylline Decrease Effectiveness
Dipyridamole May Intensify Effects
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Iron Antidote
Antidote
DeFEroxamine
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22 secs
Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
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1 min
Isoniazid
Indications
Tuberculosis (TB)
Mechanism of Action
Requires Catalase Peroxidase
Decreases Mycolic Acid Synthesis
Fast vs Slow Acetylators
Side Effects
B6 Deficiency
Neurotoxicity
Hepatotoxicity
Drug-induced Lupus
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1 min
Alpha Agonists
-RINE suffix
Norepinephrine
Hypotension
Phenylephrine
Hypotension
Congestion
Ephedrine
Congestion
Urinary Incontinence
Hypotension
Epinephrine
Anaphylaxis and Asthma
Hypotension
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1 min

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