Kevin Shared "First Aid" - 1018 Picmonics
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First Aid
Niemann-Pick Disease
- Pathophysiology
- Autosomal Recessive
- Sphingomyelinase Deficiency
- More Common in Ashkenazi Jewish Population
- Signs and Symptoms
- Cherry Red Spot on Macula
- Hepatosplenomegaly
- Neurodegeneration
- Diagnosis
- Foam Cells
1 min
Warfarin Antidotes
- Antidotes
- Vitamin K
- Fresh Frozen Plasma
59 secs
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Fabry's Disease
- Pathophysiology
- X-linked Recessive
- Alpha-galactosidase A Deficiency
- Increased Ceramide trihexoside
- Early Signs and Symptoms
- Decreased Sweating (Hypohidrosis)
- Angiokeratoma
- Episodic Peripheral Neuropathy
- Late Signs and Symptoms
- Cardiovascular Disease
- Renal Failure
1 min
Isoniazid
- Indications
- Tuberculosis (TB)
- Mechanism of Action
- Requires Catalase Peroxidase
- Decreases Mycolic Acid Synthesis
- Fast vs Slow Acetylators
- Side Effects
- B6 Deficiency
- Neurotoxicity
- Hepatotoxicity
- Drug-induced Lupus
1 min
Haemophilus ducreyi
- Characteristics
- Gram-Negative
- Coccobacillus
- Pleomorphic
- Parallel Short Chains
- School of Fish Appearance on Gram Stain
- Signs and Symptoms
- Chancroid
- Painful Genital Ulcer
- Buboes
- Treatment
- Azithromycin
- Ceftriaxone
2 mins
Bacteroides Fragilis
- Characteristics
- Gram-Negative
- Anaerobe
- Normal Colonic Flora
- Produces Vitamin K
- Produces Gas in Tissue
- Foul-Smelling
- Signs and Symptoms
- Gastrointestinal Abscess
- Treatment
- Penicillin-Resistant
- Clindamycin
- Metronidazole
2 mins
Fragile X
- Pathophysiology
- Trinucleotide Repeat
- CGG Repeats
- FMR1 Gene
- X-linked Dominant
- Signs and Symptoms
- Developmental Delay
- Autism
- Large Ears
- Large Jaw
- Long Face
- Macroorchidism
2 mins
P450 Inhibitors
- Quinidine
- Ciprofloxacin
- Isoniazid
- Grapefruit Juice
- Acute Alcohol Use
- Erythromycin (Macrolide)
- Indinavir
- Cimetidine
- Sulfonamides
- Ketoconazole
- Amiodarone
2 mins
P450 Inducer
- Griseofulvin
- Phenytoin
- Carbamazepine
- Rifampin
- Barbiturates
- Chronic Alcohol Use
- St. John's Wort
51 secs
Vitamin E Deficiency
- Mechanism
- Antioxidant
- Protects Erythrocytes
- Protects from Free Radical Damage
- Deficiency Signs and Symptoms
- Hemolytic Anemia
- Posterior Column
- Spinocerebellar Tract
2 mins
Actinomyces Israelii
- Characteristics
- Gram-Positive
- Bacillus
- Anaerobe
- Branching
- Oral Flora
- Dental Work
- Oral Trauma
- Associated with IUDs
- Signs and Symptoms
- GU Infections
- Draining Sinus Tract
- Facial Abscess
- Yellow Sulfur Granules
- Treatment
- Penicillin
2 mins
Hyper IgM Syndrome
- Pathophysiology
- Deficient CD40 Ligand on Helper T-cells
- Defective CD40 Receptor on B-cells
- Inability to Class Switch
- Signs and Symptoms
- Pyogenic Abscess
- Decreased IgG, IgA, IgE
4 mins
Hunter Syndrome
- Pathophysiology
- X-linked Recessive
- Mucopolysaccharidoses
- Iduronate Sulfatase Deficiency
- Increased Dermatan Sulfate
- Increased Heparan Sulfate
- Signs and Symptoms
- No Corneal Clouding
- Aggressive Behavior
1 min
Hurler Syndrome
- Pathophysiology
- Autosomal Recessive
- Mucopolysaccharidoses
- Alpha-L-Iduronidase Deficiency
- Increased Heparan Sulfate
- Increased Dermatan Sulfate
- Signs and Symptoms
- Hepatosplenomegaly
- Developmental Delay
- Gargoylism
- Corneal Clouding
- Airway Obstruction
2 mins
IL-12 Receptor Deficiency
- Pathophysiology
- IL-12 Secreted by Macrophages
- Decreased Th1 Response
- Decreased IFN Gamma
- Signs and Symptoms
- Mycobacterial Infections
- Salmonella
1 min
McArdles Disease
- Pathophysiology
- Type V Glycogen Storage Disease
- Muscle Glycogen Phosphorylase Deficiency
- Signs and Symptoms
- Increased Glycogen in Muscle
- Painful Muscle Cramps
- Myoglobinuria
- Normal Lactic Acid
- Treatment
- Vitamin B6
2 mins
Von Gierke Disease
- Pathophysiology
- Autosomal Recessive
- Type I Glycogen Storage Disease
- Glucose-6-Phosphatase Deficiency
- Signs and Symptoms
- Increased Glycogen in Liver
- Hepatomegaly
- Enlarged Kidneys
- Severe Fasting Hypoglycemia
- Increased Triglycerides
- Increased Uric Acid (Gout)
- Increased Lactic Acid
- Doll-like Facies
- Treatment
- Continuous Oral Glucose (or Cornstarch)
- Avoid Fructose and Galactose
2 mins
Brucella
- Characteristics
- Gram-Negative
- Coccobacillus
- Unpasteurized milk
- Goat cheese
- Inside macrophages
- Signs and Symptoms
- Lymphadenopathy
- Granulomas
- Undulating fever
- Treatment
- Doxycycline
- Gentamicin
2 mins
Beriberi (Thiamine Deficiency)
- Thiamine Deficiency
- Dry Beriberi
- Polyneuritis
- Muscle Wasting
- Wet Beriberi
- Dilated Cardiomyopathy
- Edema
51 secs
