Olivia Shared "Patho Exam #4" - 15 Picmonics
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Patho Exam #4
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cyclosporine (Sandimmune) Side Effects
- Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
1 min
Penicillin
- Mechanism of Action
- Weakens Cell Wall
- Indications
- Gram-Positive Infections
- Prophylaxis
- Side Effects
- Pain at IM Injection Site
- Allergic Reaction
- Considerations
- Skin Tests
- Allergy ID
- Medication Education
2 mins
Cephalosporins
- Starts with "Cef-"
- Mechanism of Action
- Bactericidal
- Indications
- Gram-Positive and Gram-Negative Infections
- Side Effects
- Allergic Reactions
- Thrombophlebitis
- Bleeding
- Contraindications
- Renal Impairment
- Considerations
- Avoid IV Calcium with Ceftriaxone
- No Alcohol
2 mins
Imipenem and Meropenem (Carbapenems)
- Mechanism
- Carbapenems
- Broad-spectrum Antibiotic
- Bactericidal
- Indications
- Gram Positive and Gram Negative Infections
- Side Effects
- GI Distress
- Suprainfections
- Seizures
- Considerations
- Penicillin Allergy
- IV or IM Route
- Imipenem Combined with Cilastatin
3 mins
Vancomycin
- Mechanism of Action
- Inhibits Bacterial Cell Wall Synthesis
- Indications
- Serious Gram-Positive Infections
- Side Effects
- Nephrotoxicity
- Ototoxicity
- Red Man Syndrome
- Thrombophlebitis
- Nursing Considerations
- Culture Samples First
- Infuse IV Over 60 Minutes
- Take Around the Clock
2 mins
Tetracyclines Overview
- End in "-cycline"
- Mechanism of Action
- Bacteriostatic
- Indications
- Infectious Diseases
- Acne
- Periodontal Disease
- Nursing Considerations
- Avoid Milk, Antacids, Iron
- Sunlight Protection
1 min
Tetracyclines Side Effects
- Side Effects
- Superinfection
- Clostridioides difficile
- Discoloration of Teeth
- Bone Deformities
- Photosensitivity
- Contraindications
- Children Under 8
- Pregnancy
1 min
Macrolides
- End in "-thromycin"
- Mechanism of Action
- Bacteriostatic
- Indications
- Alternative for Penicillin Allergy
- Respiratory Infections
- Pneumonia
- Side Effects
- QT Prolongation and Sudden Death
- C.Diff Overgrowth
- GI Distress
- Considerations
- Slow IV Infusion
2 mins
Aminoglycoside Side Effects
- Side Effects
- Ototoxicity
- Nephrotoxicity
- Respiratory Paralysis
- Contraindications
- Pregnancy
- Considerations
- Peak and Trough
- Never Mix with Penicillin in Same IV
2 mins
Aminoglycoside Overview
- End in "-mycin"
- GNATS
- Gentamicin
- Neomycin
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Requires Oxygen for Uptake
- Synergistic with β-lactam Antibiotics
- Indications
- Severe Gram-Negative Infections
- Bowel Surgery Prep
- MECHANISM OF RESISTANCE
- Bacterial Transferases
3 mins
Fluoroquinolones
- End in "-floxacin"
- Mechanism of Action
- Bactericidal
- Indications
- Variety of Infections
- Side Effects
- GI Distress
- Photosensitivity
- Achilles Tendon Rupture
- Contraindications
- Pregnancy
- Children
- Myasthenia Gravis
- Considerations
- Avoid Milk Products or Antacids
- Slow IV Infusion
2 mins
Isoniazid (INH)
- Mechanism
- Interferes with DNA Metabolism
- Indications
- Tuberculosis (TB)
- Side Effects
- Optic Neuritis
- Nausea and Vomiting
- Hepatotoxicity
- Peripheral Neuropathy
- Considerations
- Vitamin B6 Prophylaxis
- Monitor AST/ALT
2 mins
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Raloxifene
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Agonist in Bone
- Antagonist in Breast and Uterus
- Indications
- Osteoporosis
- Breast Cancer Prophylaxis
- Uterine Fibroids
- Side Effects
- Hot Flashes
- Thromboembolism
2 mins
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