Silvester Shared "PHYS1" - 29 Picmonics
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PHYS1
Hartnup Disease
- Pathophysiology
- Autosomal Recessive
- Neutral amino acids
- Defective Transporter
- Renal and Intestinal cells
- Signs and Symptoms
- Causes tryptophan excretion in urine
- Leads to Pellagra
- Diarrhea
- Dermatitis
- Dementia
2 mins
GI Absorption
- Stomach
- Alcohol
- Duodenum
- Iron
- Jejunum
- Folate
- Terminal Ileum
- Vitamin B12
- Bile Resorption
1 min
Oral Cavity
- Characteristics
- Mouth
- Mechanical Digestion
- Salivary Amylase Begins Carbohydrate Breakdown
- Lingual Lipase Begins Lipid Breakdown
- Esophagus
- Bolus
- Peristalsis
1 min
Stomach Digestion
- Characteristics
- Chief Cells Secrete Pepsinogen
- Pepsinogen Turned to Pepsin By H+
- Protein Breakdown Begins
- Mucous Cells Secrete Mucus and Bicarbonate
- G Cells Secrete Gastrin
- Gastrin Stimulates Parietal Cell HCl Release
- Parietal Cells Secrete Intrinsic Factor
2 mins
Small Intestine Absorption
- Characteristics
- Carbohydrates Undergo Active Transport
- Amino Acids Undergo Active Transport
- Small Lipids Undergo Passive Diffusion
- Epithelial Cells
- Intestinal Capillaries
- Hepatic Portal Transports Nutrients
- Liver
- Large Lipids Transported as Chylomicrons
- Lacteals Transport Chylomicrons
2 mins
Small Intestine Digestion
- Brush border enzymes
- Pancreatic Enzymes are secreted via a Duct
- Pancreas secretes bicarbonate
- Brush Border activates Pancreatic Trypsin
- Trypsin activates Chymotrypsin
- Trypsin and Chymotrypsin digest Proteins
- Gallbladder Releases Bile
- Pancreatic Lipase breaks down Lipids
- Goblet cells secrete mucus
- Pancreatic Amylase breaks down Carbohydrates
- Pancreatic Nucleases breakdown DNA/RNA
- Digestion occurs in the Duodenum
2 mins
Large Intestine
- Characteristics
- Colon
- Electrolyte Reabsorption
- Water Reabsorption
- Microflora Produce Vitamins
- Rectum Stores Feces
1 min
Autonomic Nervous System
- Characteristics
- Sympathetic Nervous System
- Fight or Flight
- All Preganglionic Neurons Release Acetylcholine
- Sympathetic Postganglionic Neurons Release Norepinephrine
- Antagonistic Effects of Sympathetic and Parasympathetic Nervous Systems
- Parasympathetic Nervous System
- Rest and Digest
- Parasympathetic Postganglionic Neurons Release Acetylcholine
2 mins
Vitamin D Metabolism/Mechanism
- Mechanism Of Action
- Ergocalciferol (Vitamin D2)
- Plant Sources
- Cholecalciferol (Vitamin D3)
- Sunlight Conversion in Skin
- 7-Dehydrocholesterol
- Liver Hydroxylation
- 25-(OH) D (25-hydroxyvitamin D)
- Storage Form
- Kidney Hydroxylation
- 1,25-(OH)2 D (1,25-dihydroxyvitamin D)
- Active Form Calcitriol
- Absorbs Calcium and Phosphorus in Intestine
4 mins
Malignant Hyperthermia
- Inheritance
- Autosomal-Dominant
- Pathophysiology and causes
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Symptoms
- Autonomic Instability
- Muscle Rigidity
- Treatment
- Dantrolene
2 mins
Horner Syndrome
- Pathophysiology
- Sympathetic Disruption
- Hypothalamus
- Ciliospinal Center
- Superior Cervical Ganglion
- Ocular Muscles
- Clinical Triad
- Ptosis
- Anhidrosis
- Miosis
- Diagnosis
- Diagnosis by Clinical Impression
- MRI
- Management
- Treat Underlying Disorders
3 mins
Parts of an ECG
- PQRST
- P Wave
- Atrial Depolarization
- QRS Complex
- Ventricular Depolarization
- T Wave
- Ventricular Repolarization
2 mins
ECG Interpretation
- Rate
- Rhythm
- P Waves
- Upright, Rounded, Before Every QRS
- PR Interval (< 0.20 seconds)
- Normal QRS (< 0.12 seconds)
2 mins
ECG: Sinus Bradycardia
- Rate
- < 60 bpm
- Rhythm
- Regular
- P Wave
- Present, Upright, Every QRS
- PR Interval
- < 0.20 seconds
- QRS Interval
- < 0.12 seconds
- Treatment
- Atropine
1 min
ECG: Sinus Tachycardia
- Rate
- > 100 bpm
- Rhythm
- Regular
- P Wave
- Present, Upright, Every QRS
- PR Interval
- < 0.20 seconds
- QRS Interval
- < 0.12 seconds
- Treatment
- Treat Underlying Cause
2 mins
ECG: Atrial Flutter
- Rate
- Variable
- Rhythm
- Regular or Irregular
- P Wave
- Saw Tooth, Multiple Before Every QRS
- PR Interval
- Non-measurable
- QRS Interval
- < 0.12 seconds
2 mins
ECG: Atrial Fibrillation
- Rate
- Variable Rate
- Rhythm
- Irregular Rhythm
- P Wave
- No P Wave
- PR Interval
- No PR Interval
- QRS Interval
- QRS < 0.12 Seconds
1 min
Congenital Long QT Syndrome
- PATHOGENESIS
- Inherited Disorder of Myocardial Repolarization
- Potassium (K+) Channel Mutations
- SYMPTOMS
- Prolonged QT Interval
- Torsades de Pointes
- Increased Risk of Sudden Cardiac Death (SCD)
- TYPES OF SYNDROMES
- Romano-Ward Syndrome
- Autosomal Dominant
- Pure Cardiac Phenotype (No Deafness)
- Jervell and Lange-Nielsen Syndrome
- Autosomal Recessive
- Sensorineural Deafness
4 mins
Cardiac Cycle - Systole
- Characteristics
- AV Node
- AV Node Conducts Signal to Bundle of His
- Bundle of His Signals Purkinje Fibers to Contract Ventricles
- Tricuspid Valve Closes
- Pulmonary Valve Opens
- Mitral Valve Closes
- Aortic Valve Opens
2 mins
Cardiac Cycle - Diastole
- Characteristics
- Aortic Valve Closes
- Pulmonary Valve Closes
- Ventricles Relax
- Mitral Valve Opens
- Tricuspid Valve Opens
- Ventricles Fill
- Sinoatrial (SA) Node Fires
- Atrial Contraction
3 mins
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