Clayton Shared "Microbiology Exam 2" - 35 Picmonics
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Microbiology Exam 2
Fungi Basic Characteristics
- Characteristics
- Hyphae
- Mycelium
- Septa
- Chitin
- Saprophytic
- Digestive Enzymes
- Sexual Reproduction
- Haploid Spores
- Yeast Budding
2 mins
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Amphotericin B
- Indications
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
1 min
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Pityriasis Versicolor (Tinea versicolor)
- Mechanism
- Lipid-Dependent Fungus
- Fatty Acids Damage Melanocytes
- Malassezia Furfur
- Hot, Humid Weather
- Signs and Symptoms
- Hypopigmentation
- Hyperpigmented Patches
- Diagnosis
- Spaghetti and Meatball Appearance on KOH Prep
- Fragmented Hyphae with Clusters of Yeast
- Treatment
- Topical or Oral Antifungals
- Selenium Sulfide
- Zinc
4 mins
Sporothrix Schenckii
- Characteristics
- Fungi
- Thermally Dimorphic
- Cigar-shaped Yeast Forms
- Rose Thorn Prick
- Packaging Peat Moss
- Signs & Symptoms
- Local Pustule or Ulcer
- Nodules on Draining Lymphatics
- Treatment
- Potassium Iodide
- Itraconazole
2 mins
Histoplasmosis
- Fungi
- 2-5 um
- Yeast Cells within Macrophages
- Starling Bird Poop
- Bat Poop
- Caves
- Mississippi and Ohio River Valleys
- Pneumonia
- Caseating Granuloma
- Erythema Nodosum
1 min
Blastomyces
- Characteristics
- Fungi
- Hyphae Form at 20°-25°C
- Yeast Form at 37°C
- Round Yeast
- 5-15 Micrometer (um or μm)
- Single Broad-Based Buds
- Thick Doubly-Refractive Walls
- East of the Mississippi River and Around the Great Lakes
- Signs and Symptoms
- Pneumonia
- Skin Infection
- Bone Infection
- Granulomatous Response
- Treatment
- Itraconazole
- Amphotericin B
3 mins
Coccidioidomycosis
- Characteristics
- Fungi
- Dimorphic
- Southwest
- After earthquakes
- Spherule
- 20-60 um
- Signs and Symptoms
- Pneumonia
- Meningitis
- Bone Infection
- Skin infections
- Erythema Nodosum
- Granulomatous Inflammation
- Caseous Necrosis
2 mins
Candida Albicans
- Fungi
- Yeast with Pseudohyphae at 20 Degrees C
- Germ Tube Formation at 37 Degrees C
- Pruritic Vaginitis
- White Cottage Cheese Discharge
- Fiery Red Mucosa
- Diabetics
- Antibiotic Use
- Esophageal Thrush in Immunocompromised
- Diaper Rash
- Endocarditis in IV Drug Users
2 mins
Chronic Mucocutaneous Candidiasis
- Mechanism and Characteristics
- T Cell Dysfunction
- Candida Albicans
- Signs and Symptoms
- Infections of Skin
- Infections of Mucous Membrane
- Susceptible to HPV Infections like Condyloma Acuminatum
42 secs
Cryptococcus neoformans
- Characteristics
- Monomorphic
- Encapsulated
- Polysaccharide Capsule
- Narrow-Based Buds
- Latex Agglutination
- Pigeons
- India Ink
- Mucicarmine stain
- Signs and Symptoms
- AIDS/Immunocompromised
- Meningitis
- Soap Bubble Lesions in Brain
- Pneumonia
- Treatment
- Fluconazole
- Flucytosine
- Amphotericin
3 mins
Aspergillus fumigatus
- Characteristics
- Fungi
- Monomorphic
- Septate Hyphae
- Branch at Acute Angles
- Fruiting Bodies
- Disease
- Allergic Bronchopulmonary Aspergillosis (ABPA)
- Eosinophilia
- Increased IgE
- Glucocorticoids +/- Azoles
- Pulmonary Aspergillosis
- TB Cavity
- Lung Aspergilloma
- Hemoptysis
- Invasive Aspergillosis
- AIDS/Immunocompromised
- Chronic Granulomatous Disease
- Hemorrhagic Infarction
- Necrotizing Bronchopneumonia
- Voriconazole +/- Caspofungin
3 mins
Pneumocystis jirovecii
- Fungi
- AIDS/Immunocompromised
- Fever
- Hypoxemia
- Bronchoalveolar Lavage
- Biopsy
- Methenamine Silver Stain
- Saucer/cup shaped yeast forms
- Diffuse interstitial pneumonia CXR
- TMP-SMX
- Start prophylaxis when CD4 drops under 200
1 min
Mucor and Rhizopus
- Characteristics
- Fungi
- Irregular Non-septate Hyphae
- Branching Wide Angles over 90 degrees
- Signs and Symptoms
- Leukemic Patients
- Proliferate due to excess ketones and glucose
- Diabetic Ketoacidosis (DKA)
- Rhinocerebral frontal lobe abscess
- Penetrate cribriform plate into brain
- Black Necrotic Eschars on Face
2 mins
Paracoccidioido-mycosis
- Fungi
- Latin America
- Common in Brazil
- Budding yeast with captain wheel formation
- 40-50 um
- Pneumonia
39 secs
Trimethoprim
- Mechanism of Action
- Bacteriostatic
- Inhibits Bacterial Dihydrofolate Reductase
- Causes Sequential Block of Folate Synthesis
- Used in Combination with Sulfamethoxazole
- Combination Used For Recurrent Urinary Tract Infections
- Indications
- Shigella
- Salmonella
- Pneumocystis Jiroveci Pneumonia
- Side Effects
- Decrease in Red and White Blood Cells
- Alleviated with Leucovorin Rescue
2 mins
Entamoeba histolytica
- Pathophysiology
- Protozoa
- Amebiasis
- Ingestion of Cysts in Food and Water
- Signs and Symptoms
- Bloody Diarrhea
- Flask-Shaped Ulcer
- Liver Abscess
- Anchovy Paste
- RUQ Pain
- Diagnosis
- RBCs in Cytoplasm of Trophozoite
- Cyst With Four Nuclei
- Treatment
- Metronidazole
- Iodoquinol
3 mins
Naegleria Fowleri
- Pathophysiology
- Protozoa
- Rapidly Fatal Meningoencephalitis
- Swimming in Freshwater Lakes
- Travels Through Cribriform Plate
- Diagnosis
- Amoebas in CSF
- Treatment
- Amphotericin B
- Death is Still Common
1 min
Giardia lamblia
- Characteristics
- Protozoa
- Ingestion of Cysts
- Seen in Campers
- Daycare Centers
- Mental Hospitals
- Infects Small Intestine
- Signs and Symptoms
- Bloating
- Flatulence
- Fatty Diarrhea
- Diagnosis
- Crescent-shaped Protozoa Adjacent to Epithelial Brush Border
- Predisposed if Low IgA
- Treatment
- Metronidazole
3 mins
