Claudia Shared "Block I Mirco" - 25 Picmonics
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Block I Mirco
Bacillus Anthracis (Anthrax) Characteristics
- Characteristics
- Gram-Positive
- Spore-Forming
- D-glutamate Polypeptide Capsule
- Protective Antigen
- Lethal Toxin
- Edema Factor
- Increased cAMP
1 min
Bacillus Anthracis (Anthrax) Disease
- Signs and Symptoms
- Cutaneous
- Painless Black Eschar (Necrotic Lesion)
- Pulmonary
- Mediastinal Widening
- Rapidly Fatal
- Woolsorter's Disease
- Gastrointestinal
- Consuming Anthrax-infected Meat
2 mins
Bacillus Cereus Characteristics
- Gram-Positive
- Bacilli
- Endospore Forming
- B Hemolytic
- Toxins and Enterotoxins
- Reheated Rice
1 min
Bacillus Cereus Disease
- Signs and Symptoms
- Emetic Form
- Short Incubation (1-6 Hours)
- Nausea and Vomiting
- Diarrheal Form
- Long Incubation (8-16 Hours)
- Diarrhea and GI Pain
2 mins
Corynebacterium diphtheriae
- Characteristics
- Gram-Positive
- Bacillus
- Exotoxin
- ADP Ribosylation of Elongation Factor 2
- Beta Prophage
- Lysogeny
- Tellurite Agar
- Chinese Letters
- Metachromatic Blue Red Granules
- Aniline Stains Deeply Methylene Blue
- Signs and Symptoms
- Pseudomembranous Pharyngitis
- Lymphadenopathy
- Myocarditis
- Polyneuritis
3 mins
Listeria Monocytogenes Disease
- Signs and Symptoms
- Soft Cheese
- Pregnant Women Have Flu-Like Symptoms
- Pregnant Women Have GI Symptoms
- Granulomatosis Infantiseptica
- Spontaneous Abortion
- Meningitis
- Monocytes in CSF
- Treatment
- Ampicillin
2 mins
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
55 secs
Listeria Monocytogenes Characteristics
- Characteristics
- Gram Positive
- Bacillus
- Intracellular
- Survives in Cold Temperature
- Actin Rocket
- Tumbling Motility
- Catalase-Positive
- Beta-Hemolytic
- Only Gram-Positive with Endotoxin-Like Structure
2 mins
Aminoglycosides
- Drug Names
- Gentamicin
- Neomycin for Bowel Surgery Prep
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Inhibit Formation of Initiation Complex
- Cause Misreading of mRNA
- Require O2 for Uptake
- Resistance
- Resistance by Transferase Enzymes
- Acetylation
- Phosphorylation
- Adenylation
- Indications
- Gram-Negative Rod Infections
- Synergistic with B-Lactam Antibiotics
- Side Effects
- Nephrotoxicity Especially When Used with Cephalosporins
- Ototoxicity Especially When Used with Loop Diuretics
- Teratogen
5 mins
Beta-Lactamase Inhibitors
- Considerations
- Often Combined with Penicillin Antibiotics
- Drug Names
- Clavulanic Acid
- Sulbactam
- Tazobactam
51 secs
Cephalosporins Overview
- Mechanism of Action
- Beta lactam drug
- Inhibits cell wall synthesis
- Bactericidal
- Side Effects
- Hypersensitivity reactions
- Vitamin K Deficiency
- Disulfiram like reaction with Alcohol
- Increased Nephrotoxicity of Aminoglycosides
1 min
Chloramphenicol
- Mechanism
- Bacteriostatic
- Inhibits 50S Peptidyltransferase Activity
- Indications
- Meningitis
- Rocky Mountain Spotted Fever in Pregnant Women
- Side Effects
- Anemia
- Aplastic Anemia
- Gray Baby Syndrome due to Decreased UDP-Glucuronyl Transferase
- Resistance Caused by Plasmid Encoded Acetyltransferase
2 mins
Clindamycin
- Mechanism of Action
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Blocks Translocation
- Indications
- Anaerobic Infections above the Diaphragm
- Aspiration Pneumonia
- Lung Abscess
- Side Effects
- Can Cause Pseudomembranous Colitis
1 min
Fluoroquinolones Antibiotics
- -floxacin
- Mechanism of Action
- Inhibits Topoisomerase II & IV
- Bactericidal
- Indications
- Gram-negative Rods
- Pneumonia
- Gastrointestinal Infections
- Urinary Tract Infection
- Genital Infections
- Drugs
- Levofloxacin
- Ciprofloxacin
- Has Pseudomonas Coverage
- Considerations
- Avoid Polyvalent Cations
3 mins
Macrolides
- Mechanism of Action
- Bacteriostatic
- Bind to 23S rRNA of 50S Subunit
- Inhibit Protein Synthesis by Blocking Translocation
- Macrolides
- Erythromycin
- Azithromycin
- Clarithromycin
- Indications
- Gram-Positive Cocci
- Atypical Pneumonia
- Chlamydia
- Considerations
- Resistance by Methylation of 23S rRNA Binding
2 mins
Penicillin
- Gram Positive
- Spirochetes
- Bind PBPs
- Block Transpeptidase Cross-linking of Cell Wall
- Activate Autolytic Enzymes
- Bactericidal
- Hypersensitivity Reactions
- Hemolytic Anemia
- Beta-lactamase Sensitive
2 mins
Polymyxins
- Mechanism of Action
- Cationic
- Act Like Detergents
- Bind to Cell Membranes of Bacteria
- Disrupt Their Osmotic Properties
- Indications
- Resistant Gram-Negative Infections
- Side Effects
- Neurotoxicity
- Renal tubular necrosis
3 mins
Protein Synthesis Inhibitors
- Drug Names
- 30S inhibitors
- Aminoglycosides
- Tetracyclines
- 50S inhibitors
- Chloramphenicol
- Clindamycin
- Erythromycin
- Lincomycin
- Linezolid
3 mins
Sulfa Drug Allergies
- Sulfasalazine
- Sulfonylureas
- Thiazide Diuretics
- Acetazolamide
- Furosemide Diuretic
- Celecoxib
- Probenecid
49 secs
Sulfonamides Mechanisms
- Bacteriostatic
- Gram-Positive
- Gram-Negative
- Nocardia
- Chlamydia
- PABA antimetabolites
- Inhibit dihydropteroate synthase
- Sulfamethoxazole
- Sulfisoxazole
- Sulfadiazine
1 min
