David Shared "Dz of White matter" - 4 Picmonics

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Dz of White matter

Krabbe Disease
Autosomal Recessive
Galactocerebrosidase Deficiency
Increased Psychosine
Signs and Symptoms
Developmental Delay
Peripheral Neuropathy
Optic Atrophy
Globoid Cells
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1 min
Metachromatic Leukodystrophy
Autosomal Recessive
Arylsulfatase A Deficiency
Increased Cerebroside Sulfate
Signs and Symptoms
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1 min
Multiple Sclerosis Features and Mechanisms
Twice as often in Women
Presents in 20's and 30's
Northern Europeans
Unknown mechanism, genetic factor
Autoimmune Demyelination of CNS
White Matter of Brain and Spinal Cord
T Cell Mediated Inflammation
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2 mins
Multiple Sclerosis Symptoms and Diagnosis
Optic Neuritis
Internuclear Ophthalmoplegia
Scanning Speech
Urinary and Fecal Incontinence
Motor Issues (Intention Tremor, Paresis)
Numbness and Pain
Relapsing Symptoms
Gold Standard = Plaques on MRI
Increased CSF Immunoglobulins (IgG)
Oligoclonal Bands
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4 mins

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