Joel Shared "Derm Diseases/Genetic Disorders" - 10 Picmonics
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Derm Diseases/Genetic Disorders
< 10% of Body Surface Area (BSA) Involved
10-30% BSA Overlaps with Toxic Epidermal Necrolysis (TEN)
Affects Skin and Mucous Membranes
Sloughing of Skin
High Mortality Rate
IVIG (Intravenous Immunoglobulin)
Mechanism of Action
Blocks Voltage-Gated Na+ Channels
Melanoma Mechanism and Characteristics
Associated with Sunlight Exposure
Mutation in B-RAF kinase
Large Number of Moles
Fair-Skinned people at higher risk
Radial Growth Phase
Vertical Growth Phase
Depth of tumor correlates with risk of metastasis
Diameter > 6mm
Evolution over time
S-100 Tumor Marker
LDH (Lactate Dehydrogenase) Screens for Metastasis
Wide Local Excision
Papules or Plaques
Precursor to Squamous Cell Carcinoma
Pregnancy or OCP Use
30-60 year olds
Signs & Symptoms
Plaques or Papules
Purple & Polygonal
Often Mucosal or Genital Involvement
Sawtooth Infiltrate of Lymphocytes
Hepatitis C Association
Linear Deposits of IgG
Epidermal Basement Membrane
Tense Blisters on Skin
Rarely Affect Oral Mucosa
Preceded by Upper Respiratory Tract Infection
Single "Herald Patch"
"Christmas Tree" Distribution
Plaques with Collarette Scale
Self-resolving in 6-8 Weeks
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
Open Wound Care
Administer Analgesic Prior to Wound Care
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