Andrea Shared "Pharm II Final" - 91 Picmonics
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Pharm II Final
Barbiturates
- Barb- Drug Names
- Indications
- Seizure Treatment
- Anesthesia Induction
- Mechanism of Action
- Increased Duration of Cl- Channel Opening
- Decrease Neuron Firing
- Side Effects
- Sedation
- Cardiovascular and Respiratory Depression
- CNS Depression
- P450 inducer
2 mins
Phenobarbital (Barbiturates)
- Mechanism
- Barbiturate
- Indications
- Seizures
- Side Effects
- Ataxia
- Paradoxical Excitement
- Fatigue/Drowsiness
- Considerations
- Monitor Plasma Levels
- High Potential for Abuse
1 min
Benzodiazepines Overview
- Indications
- First Line for Status Epilepticus
- Anesthesia Induction
- Anxiety
- Eclampsia
- Detoxification
- Mechanism of Action
- '-zepam' and '-zolam' Suffix
- Increase Frequency of Cl- Channel Opening
- Side Effects
- Decrease REM Sleep
- CNS Depression
- Dependence
- Antidote
- Flumazenil for Overdose
2 mins
Short-acting Benzodiazepines
- Mnemonic
- ATOM
- Drug Names
- Alprazolam
- Triazolam
- Oxazepam
- Midazolam
- Indications
- Anesthesia Induction
- Insomnia
- Anxiety
- Considerations
- Half-life < 12 Hours
- Dependence
2 mins
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Buspirone
- Indications
- Generalized Anxiety
- Mechanism of Action
- Releases Dopamine and NE
- Stimulates 5-HT1A receptors
- Side Effects
- Low Side Effect Profile
- Safer with Alcohol than Other Anxiolytics
1 min
Trazodone
- Indications
- Insomnia
- Depression
- Mechanism of Action
- Inhibit Serotonin Reuptake
- Alpha-1 Blocker
- Histamine (H1) Blocker
- Side Effects
- Sedation
- Orthostatic Hypotension
- Dry Mouth
- Priapism
- Arrhythmias
2 mins
Nonbenzodiazepine Hypnotics
- Indications
- Insomnia
- Mechanism of Action
- Short Half-Life
- Acts on BZ1 GABA receptor
- Less dependence
- Drugs
- Zolpidem (Ambien)
- Side Effects
- Ataxia, confusion
- Antidote
- Flumazenil for Overdose
1 min
Attention-Deficit Hyperactivity Disorder (ADHD) Interventions
- Drug Therapy
- CNS Stimulants
- Amphetamine
- Methylphenidate
- Bupropion (Wellbutrin)
- Atomoxetine (Strattera)
- Guanfacine (Intuniv)
- Considerations
- Manage Disruptive Behavior
- Provide Simple Instructions
2 mins
Gout Treatment
- Acute (Acute-angle)
- NSAIDs
- Glucocorticoids
- Colchicine
- Impairs Leukocyte Chemotaxis
- Chronic Gout (Crone Goat)
- Inhibit Xanthine Oxidase
- Allopurinol
- Febuxostat
- Inhibit Reabsorption of Uric Acid
- Probenecid
1 min
Gout Disease
- Acute Inflammatory Monoarthritis
- Epidemiology
- Primarily in Males
- Pathophysiology
- Precipitation of Monosodium Urate Crystals
- Underexcretion of Uric Acid
- Overproduction of Uric Acid
- Negatively Birefringent, Needle-Shaped
- Symptoms
- Swollen, Red, Painful Joint
- Asymmetric Joint Distribution
- Podagra
- Tophus
- After Large Meal or Alcohol
2 mins
Pseudogout
- Pathophysiology
- > 50 Years Old
- Arthritis of Large Joints (Classically the Knee)
- Calcium Pyrophosphate Crystals
- Diagnosis
- Positively Birefringent
- Chondrocalcinosis (On X-ray)
- Treatment
- NSAIDs
- Colchicine
- Steroids
1 min
HLA-B27 Associations
- Associations
- PAIR Acronym
- Psoriatic Arthritis
- Ankylosing Spondylitis
- Inflammatory Bowel Disease
- Reactive Arthritis
1 min
Psoriasis
- Presentation
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Histological Finding
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Treatment
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
2 mins
TNF-Alpha Inhibitors Overview
- Mechanism
- Downregulates Pro-inflammatory Cytokines
- Decreased Lymphocyte Activation and Migration
- Granuloma Breakdown
- Treats
- Crohn's Disease
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
- Psoriasis
- Ankylosing Spondylitis
1 min
Hydroxychloroquine
- Mechanism of Action
- Immunosuppressant
- Indications
- Malaria
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus (SLE)
- Porphyria Cutanea Tarda
- Side Effects
- Cardiotoxicity
- Retinopathy
- Considerations
- Ophthalmological Exams
3 mins
Bipolar Disorder Interventions
- Drug Therapy
- Lithium
- Valproic Acid (Valproate)
- Lamotrigine
- Manic Episode
- Hospitalization
- Nutrition
- Hygiene
- Depressive Episode
- Monitor for Vegetative Signs
- Suicide Precautions
2 mins
Lithium
- Indications
- Bipolar Disorder
- Mechanism of Action
- Mood Stabilizer
- Unknown Mechanism
- Side Effects
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Movement (Tremor)
- Heart Block
- Contraindication
- Pregnancy (Ebstein's Anomaly)
1 min
Gabapentin
- Primary Indication
- Seizure Treatment
- Secondary Indications
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Characteristics
- Inhibits Voltage-Gated Ca2+ channels
- Designed as a GABA Analog
- Side Effects
- Ataxia
- Sedation
2 mins
Risperidone (Risperdal)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Side Effects
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Considerations
- Intramuscular Long Acting (Depot) Form
2 mins
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