Jake Shared "B3 PHARM2" - 28 Picmonics
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B3 PHARM2
Carbamazepine
- Indications
- First-line Seizure Medication
- First Line for Trigeminal Neuralgia
- Mechanism of Action
- Stabilizes Inactive State of Na+ Channels
- Side Effects
- Stevens-Johnson Syndrome
- Induce Cytochrome P450
- Teratogen
- Hepatotoxicity
- Blood Dyscrasias
2 mins
Lamotrigine
- Indications
- Seizure Treatment
- Bipolar Disorder
- Mechanism of Action
- Blocks Voltage-Gated Na+ Channels
- Side Effect
- Stevens-Johnson Syndrome
1 min
Phenytoin
- Indications
- Status Epilepticus
- Tonic-Clonic Seizures
- Mechanism of Action
- Blocks Na+ Channel Activation
- Inhibition of Glutamate Release
- Class IB Antiarrhythmic
- Side Effects
- Teratogenic
- Macrocytic Megaloblastic Anemia
- Induce Cytochrome P450
- Drug-induced Lupus
- Neuropathy
- Hirsutism
- Gingival Hyperplasia
1 min
Topiramate
- Indications
- Seizure Treatment
- Migraine Prophylaxis
- Mechanism of Action
- Increase GABA Action
- Blocks Voltage-Gated Na+ Channels
- Side Effects
- Kidney Stones
- Weight Loss
- Sedation
1 min
Opioids Overview
- Indications
- Pain
- Weaning
- Cough
- Diarrhea
- Mechanism of Action
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Side Effects
- Respiratory Depression
- Addiction
- Miosis
- Constipation
2 mins
Morphine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Pain
- Myocardial Infarction
- Side Effects
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension
2 mins
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Benzodiazepines Overview
- Indications
- First Line for Status Epilepticus
- Anesthesia Induction
- Anxiety
- Eclampsia
- Detoxification
- Mechanism of Action
- '-zepam' and '-zolam" Suffix
- Increase Frequency of Cl- Channel Opening
- Side Effects
- Decrease REM Sleep
- CNS Depression
- Dependence
- Antidote
- Flumazenil for Overdose
2 mins
Barbiturates
- Barb- Drug Names
- Indications
- Seizure Treatment
- Anesthesia Induction
- Mechanism of Action
- Increased Duration of Cl- Channel Opening
- Decrease Neuron Firing
- Side Effects
- Sedation
- Cardiovascular and Respiratory Depression
- CNS Depression
- P450 inducer
2 mins
Phenobarbital (Barbiturates)
- Mechanism
- Barbiturate
- Indications
- Seizures
- Side Effects
- Ataxia
- Paradoxical Excitement
- Fatigue/Drowsiness
- Considerations
- Monitor Plasma Levels
- High Potential for Abuse
1 min
Valproic Acid
- Indications
- First Line Tonic-Clonic Seizure Treatment
- Bipolar Disorder
- Migraine Prophylaxis
- Mechanism of Action
- Increases GABA Concentration
- Blocks Voltage-Gated Na+ Channels
- Side Effect
- GI Distress
- Contraindication
- Contraindicated in Pregnancy
1 min
Valproic Acid (Valproate) Side Effects
- V-A-L-P-R-O-A-T-E
- Vomiting
- Alopecia
- Liver Toxicity
- Pancreatitis/Pancytopenia
- Retain Fat (Weight Gain)
- Oedema (Edema)
- Appetite Increase
- Tremor
- Enzyme Inhibitor (P450)
2 mins
Ethosuximide
- Indications
- First Line Absence Seizure Treatment
- Mechanism of Action
- Blocks Thalamic T-Type Ca2+ Channels
- Side Effects
- Stevens-Johnson Syndrome
- Fatigue
- Diarrhea
32 secs
Types of Seizures
- Tonic-clonic
- Tonic
- Clonic
- Absence (Petit Mal)
- Myoclonic
- Atonic
- Partial (Focal) Seizure
- Simple Partial
- Complex Partial
2 mins
Cluster Headache
- Presentation
- More Common in Men
- Unilateral Periorbital Headache
- Ipsilateral Tearing
- Precipitated by Alcohol
- Stabbing Pain
- Duration
- 15 min - 3 Hours
- Repetitive Attacks in Clusters
- Treatment
- High Flow 100% O2
- Ergots
- Sumatriptan
2 mins
Tension Headache
- Presentation
- More Common in Women
- Bilateral Band-like Pain
- Occipital and Neck region
- Exacerbated by Stress
- Exacerbated by Fatigue
- Duration
- > 30 Minutes
- Acute Treatment
- Relaxation
- Caffeine
- NSAIDs
- Acetaminophen
- Preventative Treatment
- Amitriptyline
1 min
Migraine Headaches Signs and Symptoms
- Signs and Symptoms
- More Common in Women
- Exacerbated by Activity
- Unilateral Pulsating Pain
- Aura
- Photophobia and Phonophobia
- Nausea/Vomiting
- Duration
- 4 hours to 3 Days
1 min
Migraine Headache Treatments
- Acute Treatment
- Avoid Triggers
- Sumatriptan
- NSAIDs
- Preventative Treatment
- Beta Blockers
- Calcium Channel Blockers
- Amitriptyline
- Topiramate (Anticonvulsants)
1 min
Opioid Antidote
- Antidote
- Naloxone
29 secs
Tramadol
- Indications
- Chronic Pain
- Mechanism of Action
- Weak Opioid
- Inhibit Serotonin and NE reuptake
- Side Effect
- Increased Risk of Seizure
48 secs
