Ariana Shared "Patho" - 47 Picmonics
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Patho
Iron Deficiency Anemia
- Causes
- Malnutrition/Malabsorption
- Hemorrhage
- Signs
- Microcytic, Hypochromic Anemia
- Decreased Heme Synthesis
- Labs
- Decreased Reticulocytes
- Decreased Ferritin
- Increased Red Cell Distribution Width (RDW)
- Poikilocytosis
- Anisocytosis
- Increased Central Pallor
2 mins
Sickle Cell Anemia Interventions
- Interventions
- Increase Hydration
- Analgesics
- Oxygen
- Warm Compress
- Bone Marrow Transplant
- Hydroxyurea
- Considerations
- Avoid High Altitudes
- Prophylactic Antibiotics
- Avoid Strenuous Exercise
- Vaccines
3 mins
Pernicious Anemia
- Vitamin B12 Deficiency
- Intrinsic factor Ab kill parietal cells
- Helicobacter pylori Associations
- Type 2 Hypersensitivity
- Triad
- Weakness
- Sore Tongue
- Paresthesia
- Macrocytic Red Blood Cells
Sickle Cell Anemia Assessment
- Cause/Mechanism
- Hemoglobin S (Genetic Defect)
- Sickle Shaped RBCs
- Assessment
- Jaundice
- Vaso Occlusive Crisis
- Fever
- Priapism
- Severe Pain
- Considerations
- Prominent in African Americans
- May be Asymptomatic
- Increased Risk of Infection
2 mins
Hemophilia
- Cause/Mechanism
- Genetic Mutation
- Assessment
- Prolonged Bleeding
- Pain
- Hemarthrosis
- Interventions
- Clotting Factor Replacement Therapy
- DDAVP (Desmopressin Acetate)
- Antifibrinolytic Therapy
- Analgesics
- Considerations
- Genetic Counseling
- Prevent Injury
3 mins
X-linked recessive diseases
- Muscular Dystrophy
- Lesch-Nyhan Syndrome
- G6PD Deficiency
- Hemophilia A and B
- red green color blindness
- Menke's disease
- OTC deficiency
- Severe Combined Immunodeficiency (SCID)
Hemophilia A, B, C
- X-linked Recessive
- A: Low Factor 8
- Hemarthrosis, Intramuscular Hematoma, Intracerebral Hemorrhage
- Mgmt: DDAVP + aminocaproic acid (anti-fibrinolytic)
- B: Low Factor 9
- C: Low Factor 11 | Autosomal Recessive
- Increased PTT (Intrinsic) ONLY
- Complications: Hemosiderin deposition, fibrosis
Erythropoietin
- Mechanism
- Stimulates RBC Production
- Indications
- Chronic Renal Failure
- Anemia
- Side Effects
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Considerations
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
2 mins
Red Blood Cell Count (RBC) Lab Values
- Women: 3.5-5.5 million cells/ MuL
- Men: 4.3-5.9 million cells/ MuL
1 min
Hemoglobin
- Hemoglobin Has Four Iron Hemes
- Lots Of Hemoglobin In Red Blood Cells
- High O2 Levels Increase O2 Binding
- High Temperature Reduces O2 Binding
- High CO2 Levels Reduce O2 Binding
- Low pH Reduces O2 Binding
- Myoglobin Binds Oxygen in Muscle
2 mins
Polycythemia Vera Disease
- Pathophysiology
- JAK2 Mutation leading to increased red blood cells
- Tyrosine Kinase
- Symptoms
- Erythromelalgia
- Pruritus
- Often After Hot Shower
- Headache
- Treatment
- Phlebotomy
- Aspirin
1 min
Neisseria gonorrhoeae Disease
- Signs & Symptoms
- Dysuria
- Pelvic Inflammatory Disease (PID)
- Fitz-Hugh-Curtis Syndrome
- Neonatal Conjunctivitis
- Pharyngitis
- Septic Arthritis
- Tenosynovitis
- Pustules On Hands And Feet
- Treatment
- Ceftriaxone
- Azithromycin
- Doxycycline
- Considerations
- C5-9 Complement Deficiency (Recurrent Infections)
2 mins
Rheumatoid Arthritis Assessment
- Mechanism
- Destruction of Connective Tissue and Synovial Membrane
- Signs and Symptoms
- Inflammation of Joints
- Morning Stiffness
- Nodules
- Joint Deformities
1 min
Systemic Lupus Erythematosus (SLE) Assessment
- Mechanism
- Multisystem Inflammatory Disorder
- Assessment
- Malar Rash
- Discoid Rash
- Arrhythmias
- Arthritis
- Hemolytic Anemia
- Seizures
- Glomerulonephritis
- Considerations
- Periods of Exacerbation and Remission
- Diagnosed by ANA (Anti-nuclear antibody assay)
2 mins
Aortic Stenosis
- Characteristics
- Age-related Calcifications
- Bicuspid Aortic Valve
- Crescendo-decrescendo Murmur
- Systolic Murmur
- Ejection Murmur
- Ejection Click
- Radiates to Carotids and Apex
- Pulsus Parvus et Tardus
- Syncope
- Helmet Cells
2 mins
Aortic Regurgitation
- Auscultation
- Diastolic Murmur
- Immediate High-pitched
- Blowing Murmur
- Clinical Findings
- Wide Pulse Pressure
- Water Hammer Pulse
- Head Bobbing
- Pulsating Nail Bed
- Considerations
- Can Cause Austin Flint Murmur
1 min
Tricuspid Regurgitation
- Holosystolic
- Blowing Murmur
- Radiates to Right Sternal Border
- Enhanced by Inspiration
1 min
Mitral Stenosis
- Characteristics
- Murmur Follows Opening Snap
- Late Diastolic Murmur
- Enhanced by Expiration
- Low-Pitched Rumbling
- Dilation of Left Atrium (LA)
- Recurrent Attacks of Rheumatic Fever
2 mins
Mitral Regurgitation
- Characteristics
- Holosystolic
- Blowing Murmur
- Loudest at Apex
- Radiates toward Axilla
- Louder by Squatting
- Hand Grip
- Expiration
1 min
Acute Pericarditis Assessment
- Pericardial Sac Inflammation
- Assessment
- Sharp Chest Pain
- Increased with Inspiration
- Pain Decreased by Leaning Forward
- Pericardial Friction Rub
- Diffuse ST-Elevation
- T Wave Inversion
- Fever
- Considerations
- May Be Asymptomatic
- Cardiac Tamponade
2 mins
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