Nigel Shared "Pathology - Block4Exam1" - 46 Picmonics

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Pathology - Block4Exam1

Takayasu's Arteritis
Pathophysiology
Granulomatous Thickening of Aortic Arch
Pulseless Disease
Asian Females
Signs and Symptoms
Fever
Myalgia
Night Sweats
Arthritis
Ocular Disturbances
Diagnosis
Increased ESR
Different Blood Pressures in Arms
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2 mins
Temporal Arteritis
Giant Cell Arteritis
Granulomatous
Old females
Polymyalgia rheumatica
Unilateral headache
Jaw claudication
Blindness
Increased ESR
Normal serum creatine kinase
Steroids
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2 mins
Polyarteritis Nodosa
Pathophysiology
Immune Complex-Mediated Transmural Vasculitis
Hepatitis B Association
Fibrinoid Necrosis
Signs and Symptoms
Black Stool (Melena)
Neurologic Dysfunction
Myalgia
Fever
Hypertension
Diagnosis
Vessels / Lesions in Different Stages
Renal Microaneurysms (On Arteriogram)
Spares Pulmonary Arteries (No Pulmonary Involvement)
Treatment
Corticosteroids
Cyclophosphamide
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2 mins
Buerger's Disease
Pathophysiology
Thromboangiitis Obliterans
Segmental Inflammation
Strong Association with Smoking
Signs and Symptoms
Superficial Nodular Phlebitis
Raynaud's Phenomenon
Autoamputation
Treatment
Smoking Cessation
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2 mins
Kawasaki Disease
Pathophysiology
Prevalent in Asian Children
Necrotizing Vasculitis
Signs and Symptoms
Fever
Strawberry-Red Tongue and Mucosa
Lymphadenopathy
Desquamative Skin Rash
Erythema and Edema of the Hands and Feet
Conjunctivitis
Coronary Aneurysm
Treatment
Intravenous Immunoglobulin (IVIG)
Aspirin
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2 mins
Granulomatosis with Polyangiitis (Wegeners) Symptoms
Signs and Symptoms
Lung Involvement
Cough
Hemoptysis
Chronic Sinusitis
Saddle Nose
Perforation of Nasal Septum
Otitis Media
Glomerulonephritis
Hematuria
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3 mins
Granulomatosis With Polyangiitis (Wegeners) Characteristics
Pathophysiology
Granulomatosis With Polyangiitis
Vasculitis
Necrotizing
C ANCA
Lungs And Upper Airway
Crescentic Glomerulonephritis
Treatment
Cyclophosphamide
Corticosteroids
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1 min
Henoch-Schonlein Purpura
Most Common Childhood Vasculitis
Follows Pharyngeal or Respiratory Infection
Palpable Purpura on Legs and Buttocks
Arthralgia
Intestinal Hemorrhage
Black Stool (Melena)
Associated with IgA Nephropathy
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2 mins
Hypersensitivity Type III
Immune Complex
Antigen-antibody (IgG) complex activates complement
Neutrophils release lysozomal enzymes
Examples
Arthus Reaction
Serum Sickness
Systemic Lupus Erythematosus (SLE)
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1 min
Hypercholesterolemia Disease
Risk Factors
Diabetes
Smoking
Family History
Hypertension
HDL < 40
Men Older than 45 Years of Age
Women Older than 55 Years of Age
Signs and Symptoms
Atheromas
Plaques in Blood Vessel Walls
Tissue Ischemia
Xanthomas
Lipemia Retinalis
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2 mins
Hypercholesterolemia Risk Stratification
0 - 1 Risk Factors
< 160 mg/dl LDL goal
greater or equal to 2 Risk Factors and 10-year Risk ≤ 20%
< 130 mg/dL LDL Goal
Coronary Heart Disease OR >/= to 2 Risk Factors AND 10-Year Risk > 20%
< 100 mg/dL LDL Goal
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2 mins
Hypercholesterolemia Treatment
Lifestyle Modifications (Diet, Exercise, Smoking Cessation)
Statins
Niacin
Ezetimibe
Fibrates
Bile Acid Resins
Screening
Men greater or equal to 35 Years Old (20-35 if at increased risk)
Women greater or equal to 45 Years Old (20-45 if at increased risk)
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2 mins
Primary Hypertension Risk Factors
Excessive Alcohol Consumption
High Sodium Diet
Dyslipidemia
Obesity
African American
Advanced Age
Vitamin D Deficiency
Reduced Nephron number
Diabetes
Lack of Physical Activity
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1 min
Hypertension Management (JNC-8)
Goal of Treatment
Age Over 60 years (and Healthy)
150/90
Age Under 60 years (and Healthy)
Any Age with Diabetes or CKD
140/90
Treatment
ARB/ACE-I/Thiazide/CCB (Primary or Combo)
CKD (w/wo Diabetes)
ARB or ACE-I Primary
African American
Thiazide or CCB Primary
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3 mins
Hypertension Assessment
Mechanism
Essential Hypertension
Secondary Hypertension
Assessment
Headache
Vision Changes
Nosebleed (Epistaxis)
Chest Pain
Syncope (Fainting)
Diagnosis
Average 2 Sets, 2 Minutes Apart
After 2 or More Visits
Nursing Considerations
Take BP Both Arms
Common in African Americans
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2 mins
Blood Pressure Classification (JNC 7)
Classifications
Normal
Systolic (< 120)
Diastolic (< 80)
Prehypertension
Systolic +20 (120-139)
Diastolic +10 (80-89)
Stage 1 Hypertension
Systolic +20 (140-159)
Diastolic +10 (90-99)
Stage 2 Hypertension
Systolic + > 20 (160)
Diastolic + > 10 (100)
Hypertensive Crisis
Systolic > 180
Diastolic > 110
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4 mins
Supine Hypotension (Vena Cava Syndrome)
Mechanism
Compression of the Vena Cava and Descending Aorta
Signs and Symptoms
Hypotension
Dizziness
Tachycardia
Decreased Renal Perfusion
Decreased Uteroplacental Perfusion
Intervention
Side-lying Position
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2 mins
Atrial Septal Defect (ASD)
Pathophysiology
Hole in Septum between the Atria
Symptoms
Often Asymptomatic
Wide and Fixed Split S2
Cyanosis and Dyspnea
Easily Fatigued
Diagnosis
Chest X-ray shows Increased Pulmonary Vascular Markings
Echocardiogram
Treatment
Surgery if CHF as Child
Antibiotic Prophylaxis
Most Close Spontaneously
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2 mins
Ventricular Septal Defect (VSD)
Pathophysiology
Opening at Intraventricular Septum
Most Common Congenital Heart lesion
Symptoms
High-pitched Holosystolic Murmer (over left sternal border)
Dyspnea and Respiratory Distress
Loud Pulmonic S2
Diagnosis
Echocardiogram
Treatment
Small VSDs Close Spontaneously
Large VSDs Require Surgery
Complications
Endocarditis
Eisenmenger's Syndrome
CHF
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2 mins
Patent Ductus Arteriosus
Continuous
Machine like murmur
Often Due to Congenital Rubella
Prematurity
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1 min

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