Nigel Shared "Pathology - Block4Exam1" - 46 Picmonics
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Pathology - Block4Exam1
Takayasu Arteritis
- Pathophysiology
- Granulomatous Thickening of Aortic Arch
- Pulseless Disease
- Asian Females
- Signs and Symptoms
- Fever
- Myalgia
- Night Sweats
- Arthritis
- Ocular Disturbances
- Diagnosis
- Increased ESR
- Different Blood Pressures in Arms
2 mins
Temporal Arteritis
- Giant Cell Arteritis
- Granulomatous
- Old Females
- Clinical Features
- Polymyalgia Rheumatica
- Unilateral Headache
- Jaw Claudication
- Blindness
- Lab Findings
- Increased ESR
- Normal Serum Creatine Kinase
- Treatment
- Steroids
2 mins
Polyarteritis Nodosa
- Pathophysiology
- Immune Complex-Mediated Transmural Vasculitis
- Hepatitis B Association
- Fibrinoid Necrosis
- Signs and Symptoms
- Black Stool (Melena)
- Neurologic Dysfunction
- Myalgia
- Fever
- Hypertension
- Diagnosis
- Vessels / Lesions in Different Stages
- Renal Microaneurysms (On Arteriogram)
- Spares Pulmonary Arteries (No Pulmonary Involvement)
- Treatment
- Corticosteroids
- Cyclophosphamide
2 mins
Buerger's Disease
- Pathophysiology
- Thromboangiitis Obliterans
- Segmental Inflammation
- Strong Association with Smoking
- Signs and Symptoms
- Superficial Nodular Phlebitis
- Raynaud's Phenomenon
- Autoamputation
- Treatment
- Smoking Cessation
2 mins
Kawasaki Disease
- Pathophysiology
- Prevalent in Asian Children
- Necrotizing Vasculitis
- Signs and Symptoms
- Fever
- Strawberry-Red Tongue and Mucosa
- Lymphadenopathy
- Desquamative Skin Rash
- Erythema and Edema of the Hands and Feet
- Conjunctivitis
- Coronary Aneurysm
- Treatment
- Intravenous Immunoglobulin (IVIG)
- Aspirin
2 mins
Granulomatosis with Polyangiitis (GPA) Symptoms
- Upper Respiratory Tract
- Saddle Nose
- Perforation of Nasal Septum
- Chronic Sinusitis
- Otitis Media
- Mastoiditis
- Lower Respiratory Tract
- Cough
- Dyspnea
- Hemoptysis
- Kidney
- Rapidly Progressive Glomerulonephritis
- Hematuria
- RBC Casts
2 mins
Granulomatosis with Polyangiitis (GPA) Characteristics
- Pathophysiology
- Small Vessel Vasculitis
- Necrotizing
- Lungs and Upper Airway
- Crescentic Glomerulonephritis
- DIAGNOSTICS
- c-ANCA
- X-ray
- Multiple Nodules in Lungs
- Treatment
- Cyclophosphamide
- Corticosteroids
- Rituximab
3 mins
Henoch-Schonlein Purpura
- Most Common Childhood Vasculitis
- Follows Pharyngeal or Respiratory Infection
- Palpable Purpura on Legs and Buttocks
- Arthralgia
- Intestinal Hemorrhage
- Black Stool (Melena)
- Associated with IgA Nephropathy
2 mins
Hypersensitivity Type III
- Immune Complex
- Antigen-antibody (IgG) complex activates complement
- Neutrophils release lysozomal enzymes
- Examples
- Arthus Reaction
- Serum Sickness
- Systemic Lupus Erythematosus (SLE)
1 min
Hypercholesterolemia Disease
- Risk Factors
- Diabetes
- Smoking
- Family History
- Hypertension
- HDL < 40
- Men Older than 45 Years of Age
- Women Older than 55 Years of Age
- Signs and Symptoms
- Atheromas
- Plaques in Blood Vessel Walls
- Tissue Ischemia
- Xanthomas
- Lipemia Retinalis
2 mins
Hypercholesterolemia Risk Stratification
- 0 - 1 Risk Factors
- < 160 mg/dl LDL goal
- greater or equal to 2 Risk Factors and 10-year Risk ≤ 20%
- < 130 mg/dL LDL Goal
- Coronary Heart Disease OR >/= to 2 Risk Factors AND 10-Year Risk > 20%
- < 100 mg/dL LDL Goal
2 mins
Hypercholesterolemia Treatment
- Lifestyle Modifications (Diet, Exercise, Smoking Cessation)
- Statins
- Niacin
- Ezetimibe
- Fibrates
- Bile Acid Resins
- PCSK9 Inhibitors
- Omega 3 Fatty Acids
- Screening
- Pooled Cohort Test
2 mins
Primary Hypertension Risk Factors
- Excessive Alcohol Consumption
- High Sodium Diet
- Dyslipidemia
- Obesity
- People of African Descent
- Advanced Age
- Vitamin D Deficiency
- Reduced Nephron Number
- Diabetes
- Lack of Physical Activity
2 mins
Hypertension Management (JNC-8)
- Goal of Treatment
- Age Over 60 years (and Healthy)
- 150/90
- Age Under 60 years (and Healthy)
- Any Age with Diabetes or CKD
- 140/90
- Treatment
- ARB/ACE-I/Thiazide/CCB (Primary or Combo)
- CKD (w/wo Diabetes)
- ARB or ACE-I Primary
- African American
- Thiazide or CCB Primary
3 mins
Hypertension Assessment
- Mechanism
- Essential Hypertension
- Secondary Hypertension
- Assessment
- Headache
- Vision Changes
- Nosebleed (Epistaxis)
- Chest Pain
- Syncope (Fainting)
- Diagnosis
- Average 2 Sets, 2 Minutes Apart
- After 2 or More Visits (within 1-4 weeks)
- Nursing Considerations
- Take BP Both Arms
- Common in African Americans
2 mins
Blood Pressure Classification (JNC 7)
- Classifications
- Normal
- Systolic (<120)
- Diastolic (< 80)
- Prehypertension
- Systolic +20 (120-139)
- Diastolic +10 (80-89)
- Stage 1 Hypertension
- Systolic +20 (140-159)
- Diastolic +10 (90-99)
- Stage 2 Hypertension
- Systolic + > 20 (160)
- Diastolic + > 10 (100)
- Hypertensive Crisis
- Systolic > 180
- Diastolic > 110
4 mins
Supine Hypotension (Vena Cava Syndrome)
- Mechanism
- Compression of the Vena Cava and Descending Aorta
- Signs and Symptoms
- Hypotension
- Dizziness
- Tachycardia
- Decreased Renal Perfusion
- Decreased Uteroplacental Perfusion
- Intervention
- Side-lying Position
2 mins
Atrial Septal Defect (ASD)
- Pathophysiology
- Hole in Septum between the Atria
- Symptoms
- Often Asymptomatic
- Wide and Fixed Split S2
- Cyanosis and Dyspnea
- Easily Fatigued
- Diagnosis
- Chest X-ray shows Increased Pulmonary Vascular Markings
- Echocardiogram
- Treatment
- Surgery if CHF as Child
- Antibiotic Prophylaxis
- Most Close Spontaneously
2 mins
Ventricular Septal Defect (VSD)
- Pathophysiology
- Opening at Intraventricular Septum
- Most Common Congenital Heart lesion
- Symptoms
- High-pitched Holosystolic Murmer (over left sternal border)
- Dyspnea and Respiratory Distress
- Loud Pulmonic S2
- Diagnosis
- Echocardiogram
- Treatment
- Small VSDs Close Spontaneously
- Large VSDs Require Surgery
- Complications
- Endocarditis
- Eisenmenger's Syndrome
- CHF
2 mins
Patent Ductus Arteriosus
- Continuous
- Machine like murmur
- Often Due to Congenital Rubella
- Prematurity
1 min
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