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Michaela Shared "GI Drugs: Laxatives & Antidiarrheals" - 5 Picmonics

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GI Drugs: Laxatives & Antidiarrheals

Osmotic Laxatives
Mechanism of Action
Increases Osmotic Load
Indications
Hepatic Encephalopathy
Constipation
Drugs
Magnesium Hydroxide
Magnesium Citrate
Polyethylene Glycol
Sorbitol
Lactulose
Side Effects
Diarrhea
Dehydration
Considerations
Misused in Bulimia Nervosa
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2 mins
Stimulant Laxatives
Irritants to increase peristalsis
Within a few hours
High dependency risk
Fast-acting, effective, inexpensive
Abdominal cramps, dependency, bowel urgency
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1 min
Bulk-forming laxatives
Indications
Constipation (small, hard stools (C))
Drug Names
Psyllium
Methylcellulose
Mechanism of Action
Soluble fibers
Draws water into gut lumen
Forms a viscous liquid that promotes peristalsis
Side Effects
Bloating
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Docusate (Emoillent) and Senna (Stimulants)
Laxative for constipation
Irritate lumen of the colon (C)
Peristaltic contractions (C)
Diarrhea (SE)
Docusate information
Osmotic draw into lumen increases water absorption by stool
Senna information
Enteric nerve stimulation leads to colonic contraction
Melanosis coli
Other drugs (C)
Castor oil (C)
Cascara sagrada (C)
Bisacodyl (C)
Phenolphthalein (C)
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Antidiarrheals
Bismuth Salicylate
Black tongue and stools
Ototoxicity
Reye syndrome with pepto bismol
Pectin and Kaolin
Cholestyramine
teeth discoloration
Atropine-Diphenoxylate
Loperamide
Not for kids
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