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Cell-mediated Adaptive Immune Response
Macrophages and Dendritic Cells Present Antigens
T Cell Develops Antigen Specificity
Regulatory T Cells Suppress Response
Memory T Cells Cause Faster Secondary Response
Cytotoxic T Cells Lyse Infected Cells
Infected Cells Present Antigen On Surface
Pathogens Infect Tissue
Mast Cells Release Histamine
Histamine Dilates and Increases Capillary Permeability
Macrophages Engulf Pathogens
Macrophage Signals Cells With Cytokines
Responding Neutrophils Cross Capillary Wall
B And T Lymphocytes Arrive At Injury Site
Pharyngeal Infection with Strep Pyogenes (Group A Strep)
Rheumatic Heart Disease
Signs and Symptoms
Early Death Due to Myocarditis
Antibodies to Acetylcholine Receptor
Weakness with Muscle Use
Hypothyroidism with Bouts of Hyperthyroidism
Enlarged, Nontender Thyroid
Anti-Thyroid Peroxidase (TPO)
HLA-DR5 and HLA-DR3
Increased Risk Of Non-Hodgkin Lymphoma
Multiple Sclerosis Features and Mechanisms
Twice as often in Women
Presents in 20's and 30's
Unknown mechanism, genetic factor
Autoimmune Demyelination of CNS
White Matter of Brain and Spinal Cord
T Cell Mediated Inflammation
Systemic Lupus Erythematosus (SLE) Mechanism, Treatment and Complications
Mechanism and Characteristics
Systemic Autoimmune Disease
9:1 female to male ratio
Secondary Antiphospholipid Antibody Syndrome
Systemic Lupus Erythematosus (SLE) Diagnosis and Clinical Features
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