Kate Shared "WGU 441 part 2" - 46 Picmonics
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WGU 441 part 2
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Osmotic Laxatives
- Mechanism of Action
- Increases Osmotic Load
- Indications
- Hepatic Encephalopathy
- Constipation
- Drugs
- Magnesium Hydroxide
- Magnesium Citrate
- Polyethylene Glycol
- Sorbitol
- Lactulose
- Side Effects
- Diarrhea
- Dehydration
- Considerations
- Misused in Bulimia Nervosa
2 mins
Oxycodone
- Mechanism of Action
- Opioid Receptor Agonist
- Indication
- Refractory Pain
- Side Effects
- Respiratory Depression
- Constipation
- CNS Depression
- Considerations
- Addiction
- Naloxone
2 mins
P450 Inhibitors
- Quinidine
- Ciprofloxacin
- Isoniazid
- Grapefruit Juice
- Acute Alcohol Use
- Erythromycin (Macrolide)
- Indinavir
- Cimetidine
- Sulfonamides
- Ketoconazole
- Amiodarone
2 mins
Parenteral Medications
- Intravenous (IV)
- Fast-Acting
- Greatest Risk
- Intramuscular (IM)
- Common Injections Sites: Deltoid, Vastus Lateralis, Ventrogluteal, and Dorsogluteal Muscles
- Absorbed Fast
- Vaccines and Epinephrine
- 3 mL Limit
- Subcutaneous (SC)
- Common Injections Sites: Abdomen, Arm, and Thigh
- Absorbed Slower
- Insulin and Hormones
- Small Volumes
- Intradermal (ID)
- Common Injection Sites: Back of Forearm and Upper Back
- Longest to Absorb
- Tuberculosis and Allergy Testing
- Under 0.5 mL
5 mins
Physiologic Dead Space (VD)
- Tidal Volume (Vt)
- Partial Pressure of Arterial CO2 (PaCO2)
- Partial Pressure of CO2 in Expired Air (PECO2)
- VD = VT x (PaCO2-PECO2) / PaCO2
2 mins
Pilocarpine (Pilocar)
- Mechanism
- Direct Cholinergic Agonist
- Contracts Iris Sphincter
- Contracts Ciliary Muscle
- Indications
- Xerostomia
- Glaucoma
- Side Effects
- Detached Retina
- Decreased Visual Acuity
- Eye Irritation
- Cholinergic Effects
- Considerations
- Avoid with Asthma or Bradycardia
2 mins
Pramlintide (Symlin)
- Mechanism
- Synthetic Amylin Analog
- Indications
- Diabetes Type 1 and 2
- Supplement Mealtime Insulin
- Side Effects
- Nausea
- Skin Reactions at Injection Site
- Considerations
- Hypoglycemia When Combined with Insulin
- Delayed Absorption of Oral Drugs
2 mins
Prazosin (Minipress)
- -osin suffix
- Mechanisms
- Selective Alpha-1 Receptor Blocker
- Indications
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Nightmares
- Side Effects
- Orthostatic Hypotension
- Tachycardia
- Priapism / Inhibition of Ejaculation
- Nasal Congestion
- Considerations
- First Dose Effect
- Administer at Bedtime
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Propylthiouracil (PTU) and Methimazole (MMI)
- Indications
- Hyperthyroidism
- Mechanism
- Inhibits Thyroid Peroxidase
- PTU Blocks Peripheral Conversion of T4 to T3
- Side Effects
- Agranulocytosis
- Skin Rash
- Hepatotoxicity (PTU)
- Teratogen (MMI)
1 min
Reye's Syndrome
- Cause
- Aspirin (Salicylates) to Treat Viral Illness (In Children)
- Assessment
- Cerebral Edema
- Lethargy (Decreased LOC)
- Vomiting
- Liver Failure
- Interventions
- Monitor for Increased ICP
- Mannitol (Osmitrol)
- Considerations
- No Aspirin for Children
2 mins
Second Generation Antihistamines
- Indications
- Allergies
- Mechanism of Action
- Lipophobic
- Histamine H1 Receptor Antagonist
- Drugs
- Azelastine + Fluticasone (Dymista)
- Intranasal Spray
- Cetirizine (Zyrtec)
- Loratadine (Claritin)
- Fexofenadine (Allegra)
- Considerations
- Fewer Anticholinergic Effects
- Fewer CNS Effects
2 mins
Serotonin Syndrome Assessment
- Mild Signs & Symptoms
- Restlessness
- Diaphoresis
- Tachycardia
- Hypertension
- Diarrhea
- Moderate Signs & Symptoms
- Hyperthermia
- Decreased Level of Consciousness
- Muscle Rigidity
- Severe Signs & Symptoms
- Seizure and Coma
- Treatment
- Cyproheptadine
2 mins
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
- Mechanism
- Topical Antimicrobial
- Indications
- Burns
- Open Wound Care
- Side Effects
- Mafenide
- Pain
- Acidosis
- Considerations
- Administer Analgesic Prior to Wound Care
1 min
Sitagliptin (Januvia) and Saxagliptin (Onglyza) (DPP-4 Inhibitors)
- -gliptin Suffix
- Mechanisms
- DPP-4 Inhibitor
- Increases Insulin Release
- Indications
- Type 2 Diabetes
- Side Effects
- Pancreatitis
- Upper Respiratory Infection and Inflammation
- Stevens-Johnson Syndrome
- Considerations
- Used as Add-on Agents
2 mins
Sodium Nitroprusside (Nitropress)
- Mechanism
- Venous and Arterial Dilation
- Indications
- Hypertensive Crisis
- Side Effects
- Cyanide Toxicity
- Thiocyanate Toxicity
- Hypotension
- Considerations
- Short Term Administration
- Light Sensitive, Use Container
- Continuous BP Monitoring
2 mins
Spironolactone (Aldactone)
- Mechanisms
- Inhibition of Aldosterone
- Potassium Retention
- Indications
- Hypertension
- Edema
- Heart Failure
- Side Effects
- Hyperkalemia
- Endocrine Effects
- Consideration
- Avoid Potassium Supplements
2 mins
Statins
- Rhabdomyolysis
- Hepatotoxicity
- HMG-CoA reductase inhibitors
- Decrease LDL
- Decrease Triglycerides
- Increase HDL
2 mins
Succinylcholine
- Indications
- Inducing Paralysis
- Mechanism of Action
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phases of Action
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
2 mins
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