Alaine Shared "Pharm exam 3 B3" - 34 Picmonics
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Pharm exam 3 B3
Second Generation Antihistamines
- Indications
- Allergies
- Mechanism of Action
- Lipophobic
- Histamine H1 Receptor Antagonist
- Drugs
- Azelastine + Fluticasone (Dymista)
- Intranasal Spray
- Cetirizine (Zyrtec)
- Loratadine (Claritin)
- Fexofenadine (Allegra)
- Considerations
- Fewer Anticholinergic Effects
- Fewer CNS Effects
2 mins
First Generation Antihistamines
- Mechanism of Action
- Histamine H1 Receptor Antagonist
- Indications
- Allergies
- Nausea and Vomiting
- Motion Sickness
- Anaphylaxis
- Drug Names
- Diphenhydramine (Benadryl)
- Promethazine (Phenergan)
- Chlorpheniramine
- Side Effects
- Sedation
- Anticholinergic Effects
2 mins
Phenylephrine
- Mechanism of Action
- Alpha-1 Agonist
- Indications
- Mydriatic
- Rhinitis
- Hypotension
- Decreased Chronotropy and Inotropy
2 mins
Ephedrine
- Mechanism of Action
- Alpha Agonist
- Beta Agonist
- Indications
- Rhinitis
- Hypotension
- Urinary Incontinence
35 secs
Alpha Agonists
- -RINE suffix
- Norepinephrine
- Hypotension
- Phenylephrine
- Hypotension
- Congestion
- Ephedrine
- Congestion
- Urinary Incontinence
- Hypotension
- Epinephrine
- Anaphylaxis and Asthma
- Hypotension
1 min
Cromolyn (Mast Cell Stabilizers)
- Mechanism
- Mast Cell Stabilizer
- Indications
- Asthma Prophylaxis
- Bronchial Inflammation
- Allergic Rhinitis
- Side Effects
- Cough
- Bronchospasm
- Consideration
- Fixed Schedule Administration
2 mins
Anticholinergics Continued
- Drugs
- Glycopyrrolate
- Reduces Airway Secretions
- Ulcer Treatment
- Ipratropium
- Asthma and C.O.P.D
- Dicyclomine
- Hyoscyamine
- Irritable Bowel Syndrome
1 min
Stages of Asthma Treatments
- Mild Intermittent
- Short-acting Inhaled Beta-Agonist
- Mild Persistent
- Low-Dose Inhaled Corticosteroid
- Montelukast (Leukotriene Receptor Antagonist)
- Moderate Persistent
- Low to Medium-dose Inhaled Corticosteroid
- Zileuton
- Severe Persistent
- High-Dose Inhaled Corticosteroid
- Systemic Corticosteroids
- Omalizumab (Allergies)
2 mins
Montelukast (Singulair)
- Mechanism
- Leukotriene Receptor Blocker
- Indications
- Allergic Rhinitis
- Asthma Prophylaxis
- Exercise Induced Bronchospasm
- Side Effects
- Fatigue
- Headache
- Mood Changes
- Suicidal Thoughts
- Considerations
- Increased Risk of Churg Strauss
2 mins
Codeine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Mild to Moderate Pain
- Cough Suppressant
- Side Effects
- Sedation
- Constipation
- Miosis
- Considerations
- Close Monitoring When Breast Feeding
- Often Combined with Non-Opioids
2 mins
Nonselective Beta-Blockers
- "-olol" Suffix
- Nonselective
- Propranolol
- Timolol
- Nadolol
- Partial β Agonist
- Pindolol
- Nonselective β with α Blocking
- Carvedilol
- Labetalol
2 mins
Systemic Effects of Beta-Blockers
- Respiratory
- Bronchoconstriction
- Metabolic
- Decreased Insulin
- Decreased Glycolysis and Lipolysis
- Eye
- Reduces Intraocular Pressure
1 min
Selective Beta-1 Blockers
- Characteristics
- "-olol" Suffix
- Drug Names
- Beta-1 Selective
- Atenolol
- Esmolol
- Metoprolol
- Partial Beta agonists
- Acebutolol
1 min
Alpha 2 Receptor
- Characteristics
- Gi Subunit
- Decrease Sympathetic Outflow
- Decrease Insulin Release
- Decrease Lipolysis
- Increase Platelet Aggregation
- Decrease Aqueous Humor Production
2 mins
Acetazolamide
- Indications
- Glaucoma
- Altitude Sickness
- Pseudotumor Cerebri
- CHF
- Metabolic Alkalosis
- Mechanism of Action
- Carbonic Anhydrase Inhibitor
- Sodium Bicarbonate (NaHCO3) Diuresis
- Side Effects
- Metabolic Acidosis
- Paresthesias
1 min
Pilocarpine (Pilocar)
- Mechanism
- Direct Cholinergic Agonist
- Contracts Iris Sphincter
- Contracts Ciliary Muscle
- Indications
- Xerostomia
- Glaucoma
- Side Effects
- Detached Retina
- Decreased Visual Acuity
- Eye Irritation
- Cholinergic Effects
- Considerations
- Avoid with Asthma or Bradycardia
2 mins
Bevacizumab Mechanisms and Indications
- Mechanisms
- Monoclonal Antibody to VEGF
- Inhibits Angiogenesis (and Vasculogenesis)
- Indications
- Capillaries Grow CORN (CG-CORN acronym)
- Colorectal Cancer
- Glioblastoma
- Cervical Cancer
- Ovarian Cancer
- Renal Cell Carcinoma
- Non-small Cell Lung Cancer (NSCLC)
- Age-related Macular Degeneration
2 mins
Nonproliferative Diabetic Retinopathy
- Characteristics
- Increased Capillary Permeability and Leakage
- Often Asymptomatic
- Fundoscopic Findings
- Retinal Microaneurysms
- Flame-shaped Hemorrhages
- Cotton Wool Spots
- Hard Exudates
- Macular Edema
- Management
- Treat Diabetes
- Laser Photocoagulation
- Bevacizumab
3 mins
Proliferative Diabetic Retinopathy
- Characteristics
- Angiogenesis
- Increased VEGF
- Asymptomatic Until Late-stage
- Fundoscopic Findings
- Vitreous Hemorrhage
- Retinal Detachment
- Glaucoma
- Findings of Nonproliferative Diabetic Retinopathy
- Management
- Laser Photocoagulation
- Surgery
- Bevacizumab
2 mins
Aminoglycosides
- Drug Names
- Gentamicin
- Neomycin for Bowel Surgery Prep
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Inhibit Formation of Initiation Complex
- Cause Misreading of mRNA
- Require O2 for Uptake
- Resistance
- Resistance by Transferase Enzymes
- Acetylation
- Phosphorylation
- Adenylation
- Indications
- Gram-Negative Rod Infections
- Synergistic with B-Lactam Antibiotics
- Side Effects
- Nephrotoxicity Especially When Used with Cephalosporins
- Ototoxicity Especially When Used with Loop Diuretics
- Teratogen
5 mins
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