Maia Shared "290 Exam 4" - 25 Picmonics
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290 Exam 4
Supine Hypotension (Vena Cava Syndrome)
- Mechanism
- Compression of the Vena Cava and Descending Aorta
- Signs and Symptoms
- Hypotension
- Dizziness
- Tachycardia
- Decreased Renal Perfusion
- Decreased Uteroplacental Perfusion
- Intervention
- Side-lying Position
2 mins
Colorectal Cancer Assessment
- 3rd Most Common Cancer
- Assessment
- Change in Bowel Habits
- Bowel Obstruction
- Rectal Bleeding
- Anemia
- Weight Loss
- Ascites
- Considerations
- Colonoscopy
- FOBT and FIT
2 mins
Prostate Cancer Assessment
- Most Common Cancer in Men
- Assessment
- Mimics BPH
- Metastasis to Back
- Low Back Pain
- Fatigue
- Considerations
- Prostate Specific Antigen (PSA)
- Digital Rectal Examination (DRE)
- Transrectal Ultrasound (TRUS)
- Biopsy
2 mins
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cisplatin (Platinol)
- Mechanism
- Alkylating Agent
- Cross-Links DNA
- Indications
- Testicular Cancer
- Ovarian Cancer
- Side Effects
- Nausea and Vomiting
- Myelosuppression
- Nephrotoxicity
- Ototoxicity
- Peripheral Neuropathy
- Considerations
- Antiemetics Before Administration
- Aggressive Hydration
3 mins
Vincristine (Oncovin)
- Mechanism
- Vinca Alkaloid
- Inhibits Microtubules
- Indications
- Leukemias
- Lymphomas
- Side Effects
- Peripheral Neuropathy
- Paralytic Ileus
- Considerations
- Vesicant
2 mins
Erythropoietin
- Mechanism
- Stimulates RBC Production
- Indications
- Chronic Renal Failure
- Anemia
- Side Effects
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Considerations
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
2 mins
Bleomycin
- Indications
- Testicular Cancer
- Hodgkin's Lymphoma
- Mechanism of Action
- Induces Free Radical Formation
- Breaks in DNA Strands
- Side Effects
- Pulmonary Fibrosis
- Skin Changes
- Mucositis
1 min
Busulfan
- Indications
- CML
- Bone Marrow Ablation
- Mechanism
- Cross-Links DNA
- Side Effects
- Myelosuppression
- Pulmonary Fibrosis
- Hyperpigmentation
55 secs
Cyclophosphamide
- Mechanism
- Requires Bioactivation by Liver
- Cross-links DNA
- Guanine N7 Position
- Indications
- Autoimmune Disorders
- Leukemia
- Lymphoma
- Solid Tumors
- Side Effects
- Myelosuppression
- Hemorrhagic Cystitis
- Prevent with Mesna
3 mins
Hodgkin's Lymphoma Interventions
- Diagnosis
- Biopsy
- Staging
- Interventions
- Radiation
- Chemotherapy
- Treat Side Effects of Therapy
- Considerations
- Secondary Cancer Screening
2 mins
Hodgkin's Lymphoma Assessment
- Cause
- Lymph Node Cancer
- Contiguous Spread
- Assessment
- Painless Lymphadenopathy
- Constitutional B Signs
- Night Sweats
- Fever
- Weight Loss
- Considerations
- Bimodal Age Distribution
- Reed-Sternberg Cells
2 mins
Non-Hodgkin's Lymphoma Assessment
- Cause
- Lymphatic Cancer
- Non-Contiguous Spread
- B or T Cells
- Assessment
- Painless Lymphadenopathy
- Constitutional B Signs
- Night Sweats
- Fever
- Weight Loss
- Mediastinal or Abdominal Mass
- Considerations
- Older Adults
- > 60 Subtypes
2 mins
Tacrolimus (Prograf) Overview
- Mechanisms
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Transplant Rejection
- Atopic Dermatitis
- Considerations
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
1 min
Rituximab
- Indications
- Chronic Lymphocytic Leukemia (CLL)
- Non-Hodgkin Lymphoma
- Rheumatoid Arthritis
- Microscopic Polyangiitis (MPA)
- Granulomatosis with Polyangiitis (Formerly Wegener's)
- Mechanism
- Monoclonal Antibody Against CD20
- Found on B Cell Neoplasms
- Side Effects
- Infusion Reactions
- Skin and Mouth Reactions
- Reactivation of Hepatitis B Virus (HBV)
- Progressive Multifocal Leukoencephalopathy (PML)
3 mins
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Hypercalcemia Treatments
- Treat Underlying Disorder
- Hydration
- Dialysis
- Calcium Restriction
- Bisphosphonates
- Calcitonin
- Cinacalcet
- Glucocorticosteroids
- Denosumab
2 mins
Hydroxyurea
- Mechanism
- Inhibits Ribonucleotide Reductase
- Decreased DNA Synthesis
- S-phase Specific
- Indications
- Melanoma
- Chronic Myelogenous Leukemia (CML)
- Sickle Cell Disease
- Through Increased HbF (Fetal Hemoglobin)
- Side Effects
- Myelosuppression
- GI Distress
2 mins
Tamoxifen
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Antagonist on Breast Tissue
- Indications
- ER-positive Breast Cancer
- Side Effects
- Decreased Risk of Osteoporosis
- Increased Risk of Endometrial Cancer
- Increased Risk of Venous Thromboembolism (VTE)
1 min
Breast Cancer Diagnosis
- Mammography
- Ultrasound
- MRI for High Risk Patients
- Confirmed with Biopsy
- Considerations
- Lymph Node Involvement
- Receptor Positivity
- Estrogen and Progesterone Receptors
- HER-2
2 mins
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