Andrew Shared "S1 GI Week 2" - 84 Picmonics
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S1 GI Week 2
E. coli Overview
- Characteristics
- Gram-Negative
- Bacillus
- Purple Colony with Metallic Green Sheen
- Lactose-Fermenting
- Pink on MacConkey Agar
- Disease
- Diarrhea
- Lipid A Septic Shock
- P Pili Pyelonephritis and Cystitis
- K Capsule Neonatal Meningitis
- K Capsule Pneumonia
- H Antigen Flagella
2 mins
Enterohemorrhagic E. Coli (EHEC)
- Characteristics
- O157:H7
- Non-Sorbitol Fermenting
- Hamburger Meat
- Produces Shiga-like Toxin
- Gram-negative
- Lysogeny
- Inactivates 60S Ribosome
- Disease
- Bloody Diarrhea
- Hemolytic Uremic Syndrome (HUS)
- Hemolytic Anemia
- Acute Renal Failure
- Thrombocytopenia
2 mins
Salmonella Overview
- Pathophysiology
- Gram-Negative Rod
- Oxidase Negative
- Non Lactose Fermenter
- White on Macconkey Agar
- H2S Producing
- Flagella
- Invades GI Tract
- Peyer's Patches
- Considerations
- Osteomyelitis in Sickle Cell Patients
- Reactive Arthritis
- Antibiotics Prolong Fecal Excretion
3 mins
Salmonella Enterica Spp.
- Characteristics
- Animal and Human Reservoir
- Poultry and Eggs
- Turtles
- PMN Immune Response
- Symptoms
- Gastroenteritis
- Diarrhea
- Possibly Bloody
- Treatments
- No Antibiotics
- No Vaccine Available
2 mins
Salmonella Typhi
- Characteristics
- Colonizes Gallbladder
- Monocytic Immune Response
- Symptoms
- Typhoid Fever
- Abdominal Pain
- Rose Spots on Abdomen
- Constipation Followed by Diarrhea
- Treatments
- Ceftriaxone
- Fluoroquinolones
- Considerations
- Oral Vaccine - Live
- IM Vaccine - Capsular Polysaccharide
2 mins
Campylobacter jejuni
- Characteristics
- Gram-Negative
- Bacillus
- Flagella
- Curved
- Corkscrew Appearance
- Oxidase-Positive
- Grows Well at 42 Degrees
- Undercooked Meat
- Unpasteurized Milk
- Animals with Diarrhea
- Signs and Symptoms
- Bloody Diarrhea
- Guillain-Barre syndrome
- Reactive Arthritis
3 mins
Shigella
- Characteristics
- Gram-Negative
- Bacilli
- Non Lactose Fermenting
- White on Macconkey Agar
- Oxidase Negative
- Non H2S Producing
- Day Care Centers
- High Virulence
- Replicates Intracellularly
- Actin Rocket
- Signs and Symptoms
- Bloody Diarrhea
- Shiga Toxin
- Inhibits 60S Ribosome
- Hemolytic Uremic Syndrome (HUS)
- Hemolytic Anemia
- Thrombocytopenia
- Kidney Failure
3 mins
Vibrio Cholera Characteristics
- Gram-Negative
- Bacilli
- Glucose Fermenting
- Non-lactose Fermenting
- Oxidase Positive
- Comma Shaped
- Thrives in Alkaline Environment
- Crustaceans
1 min
Vibrio Cholera Disease
- ADP Ribosylating AB Toxin
- Turn Gs on Causing Increase in cAMP
- Secretion of Cl
- Blocks Reabsorption of Na
- Rice Water Diarrhea
1 min
Yersinia Enterocolitica
- Characteristics
- Gram-Negative
- Bacilli
- Non-lactose Fermenting
- Non-H2S Producing
- Oxidase-Negative
- Day Care Centers
- Pork
- Raw Milk
- Pet (Puppy) Feces
- Signs and Symptoms
- Bloody Diarrhea
- Mesenteric Adenitis
- Granulomatous Microabscess in Mesenteric Lymph Nodes
- Pseudoappendicitis (Mimics)
- Reactive Arthritis
2 mins
Clostridium perfringens
- Characteristics
- Gram-Positive
- Bacillus
- Anaerobe
- Spore-Forming
- Alpha Toxin Lecithinase
- Phospholipase
- Heat Labile Enterotoxin
- Signs and Symptoms
- Myonecrosis
- Gas Gangrene
- Food Poisoning and Diarrhea
- Treatment
- Hyperbaric O2 Chamber
2 mins
Clostridioides difficile (Clostridium difficile)
- Characteristics
- Gram-Positive
- Bacillus
- Anaerobe
- Clindamycin and Ampicillin
- Toxin A Enterotoxin
- Damages Brush Border of Gut
- Toxin B Cytotoxin
- Damages Cytoskeletal Structure
- Signs and Symptoms
- Diarrhea
- Pseudomembranous Colitis
- Toxic Megacolon
- Diagnosis
- Detect Toxins in Stool
- Treatment
- Metronidazole
- Vancomycin
3 mins
Clindamycin
- Mechanism of Action
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Blocks Translocation
- Indications
- Anaerobic Infections above the Diaphragm
- Aspiration Pneumonia
- Lung Abscess
- Side Effects
- Can Cause Pseudomembranous Colitis
1 min
Bacillus Cereus Characteristics
- Gram-Positive
- Bacilli
- Endospore Forming
- B Hemolytic
- Toxins and Enterotoxins
- Reheated Rice
1 min
Bacillus Cereus Disease
- Signs and Symptoms
- Emetic Form
- Short Incubation (1-6 Hours)
- Nausea and Vomiting
- Diarrheal Form
- Long Incubation (8-16 Hours)
- Diarrhea and GI Pain
2 mins
Staphylococcus aureus Characteristics
- Characteristics
- Gram-Positive
- Cocci
- Catalase-Positive
- Coagulase-Positive
- Beta-Hemolytic
- Protein A Virulence Factor
- Inhibits Phagocytosis
- MRSA
- Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
2 mins
Staphylococcus aureus Disease
- Skin Infections
- Impetigo
- Abscesses
- Exfoliative Toxin
- Scalded Skin Syndrome
- Toxic Shock Syndrome (TSST 1)
- Binds to MHC II and T Cell Receptor
- Food Poisoning
- Acute Bacterial Endocarditis
- Pneumonia
- Osteomyelitis
2 mins
Clostridium botulinum
- Characteristics
- Bacillus
- Gram-positive
- Anaerobe
- Spore-forming
- Heat Labile Toxin
- Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
- Canned Food in Adults
- Spores in Honey
- Signs and Symptoms
- Descending Flaccid Paralysis
- Diplopia
- Ptosis
- Floppy Baby
- Constipation
2 mins
Listeria Monocytogenes Characteristics
- Characteristics
- Gram Positive
- Bacillus
- Intracellular
- Survives in Cold Temperature
- Actin Rocket
- Tumbling Motility
- Catalase-Positive
- Beta-Hemolytic
- Only Gram-Positive with Endotoxin-Like Structure
2 mins
Listeria Monocytogenes Disease
- Signs and Symptoms
- Soft Cheese
- Pregnant Women Have Flu-Like Symptoms
- Pregnant Women Have GI Symptoms
- Granulomatosis Infantiseptica
- Spontaneous Abortion
- Meningitis
- Monocytes in CSF
- Treatment
- Ampicillin
2 mins
