Grayson Shared "Pharm" - 26 Picmonics

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Pharm

Propylthiouracil (PTU) and Methimazole (MMI)
Indications
Hyperthyroidism
Mechanism
Inhibits Thyroid Peroxidase
PTU Blocks Peripheral Conversion of T4 to T3
Side Effects
Agranulocytosis
Skin Rash
Hepatotoxicity (PTU)
Teratogen (MMI)
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1 min
Cushing's Syndrome Characteristics
More Common in Women
Exogenous Etiologies
Glucocorticoids
Endogenous Etiologies
Decreased ACTH
Primary Adrenal Disease
Increased ACTH
Pituitary Adenoma (Cushing's Disease)
Paraneoplastic: Small Cell Carcinoma
CRF-releasing Tumors
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2 mins
Prednisone (Glucocorticoids)
Mechanism
Glucocorticoid
Indications
Inflammatory Conditions
Organ Transplant Rejection
Side Effects
Cataracts and Glaucoma
Cushing's Syndrome
Osteoporosis
Immunosuppression
Hyperglycemia
Ulcers
Considerations
Adrenal Insufficiency
Taper Gradually
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2 mins
Wolff-Parkinson-White Syndrome
WPW Pattern vs. WPW Syndrome
Pathophysiology
Ventricular Pre-excitation Syndrome
Accessory Conduction Pathway
Signs & Symptoms
Supraventricular Tachycardia
Atrial Fibrillation
Diagnosis
Shortened PR Interval
Delta Wave
Widened QRS
Treatment
No Treatment if Asymptomatic
Treat Arrhythmia
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3 mins
Levothyroxine
Indications
Hypothyroidism
Myxedema Coma
Mechanism of Action
Isomer of thyroid hormone (T4)
T3 has higher potency
Side Effects
Hyperthyroid symptoms
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56 secs
Cushing's Syndrome Symptoms And Diagnosis
Symptoms/Findings
Osteoporosis
Amenorrhea
Truncal Obesity
Skin Changes
Buffalo Hump
Immune Suppression
Moon Facies
Hypertension
Decreased Insulin Sensitivity
Diagnosis
24-hour urine free Cortisol
Dexamethasone Suppression Test
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2 mins
Hypothyroidism Intervention
Medications
Levothyroxine (Synthroid)
Liothyronine (Cytomel)
Complication
Myxedema Coma
Nursing Considerations
Lifelong Replacement Hormone
Monitor Vital Signs
Fluids and Fiber
Low Calorie, Low Fat Diet
Medication Education
No Switching Brands
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2 mins
Addison's Disease
Mechanism
Chronic 1° Adrenal Insufficiency
Atrophy
Destruction
Symptoms
Deficiency In Cortisol And Aldosterone
Skin Hyperpigmentation
Increased POMC
Hypotension
Hyperkalemia
Acidosis
Addisonian Crisis
Diagnosis
ACTH (Cosyntropin) Stimulation Test
Treatment
Exogenous Cortisol
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2 mins
Hyperthyroidism Interventions
Drug Therapy
Propylthiouracil (PTU)
Methimazole (Tapazole)
Iodine
Beta Blockers
Other Therapies
Radioiodine Ablation
Thyroidectomy
Complications
Thyrotoxicosis
Post-Surgery Hypocalcemia
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2 mins
Leuprolide
Mechanism
GnRH Agonist (Pulsatile Use)
GnRH Antagonist (Continuous Use)
Upregulates FSH And LH
Downregulates FSH And LH
Indications Pulsatile
Infertility
Indications Continuous
Prostate Cancer
Precocious Puberty
Uterine Fibroids
Endometriosis
Side Effects
Anti-androgenic Effects
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2 mins
Tamoxifen
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Antagonist on Breast Tissue
Indications
ER-positive Breast Cancer
Side Effects
Decreased Risk of Osteoporosis
Increased Risk of Endometrial Cancer
Increased Risk of Venous Thromboembolism (VTE)
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1 min
Breast Cancer Interventions
Radiation or Chemotherapy
Hormonal Therapy
Tamoxifen
Lumpectomy
Mastectomy
Avoid BP and Injections Affected Arm
Hand Exercises
Considerations
Grief Related to Body Image
Prosthetics
Reconstruction
Lymphedema
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3 mins
Benign Prostatic Hyperplasia (BPH) Diagnosis and Treatment
Diagnosis
Digital Rectal Exam
Urinalysis to Detect Infection or Blood
Treatment
Alpha-1 Antagonists
Tamsulosin
5 Alpha Reductase Inhibitors
Finasteride
TURP (Transurethral Resection of Prostate)
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1 min
Zanamivir (Relenza) and Oseltamivir (Tamiflu)
Indications
Influenza A and B
Treatment and Prophylaxis
Mechanism
Inhibits Release of New Virus
Inhibits Influenza Neuraminidase
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1 min
Protease Inhibitors
End in "-navir"
Indications
HIV/AIDS
Hepatitis C
Mechanism
Inhibit Protease
Unable to Cleave Proteins
Inhibits Maturation of New Virus
Side Effects
GI Distress
Nephropathy
Lipodystrophy
Hyperglycemia
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3 mins
Open-Angle Glaucoma
Humor has access to trabecular meshwork
Presentation
Painless
African-American
Elderly
Positive family history
Primary Open-Angle Glaucoma
Most common form of Glaucoma
Unknown Mechanism
Secondary Open-Angle Glaucoma
Blocked trabecular meshwork (with Open-Angle)
WBCs
Red Blood Cells (RBC)
Retinal products
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2 mins
Closed-Angle Glaucoma
Primary
Lens causes pupillary obstruction
Aqueous humor builds behind iris
Iris bends forward, obstructing trabecular mesh
Secondary
Hypoxia Causes Neovascular Proliferation
Contraction and obstruction of trabecular mesh
Chronic disease (Crone)
Asymptomatic
Acute Disease
Eye pain and blindness
Rock-hard eye
Headache
Emergency
Epinephrine contraindicated
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2 mins
Aspirin
Indications
Fever
Pain and Headache
Cardiovascular Disease (CAD)
Mechanism of Action
Irreversible inhibition of COX-1 and COX-2
Suppress Thromboxanes and Prostaglandins
NSAID
Side Effects
Reye's Syndrome
Tinnitus
Peptic Ulceration
Mixed Acidosis/Alkalosis
Nephropathy
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2 mins
Aspirin Poisoning (Salicylism) Assessment
Early Symptoms
Nausea and Vomiting
Tinnitus
Confusion
Hyperventilation
Respiratory Alkalosis
Late Symptoms
Metabolic Acidosis
Coma
Hyperthermia
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1 min
Serotonin Syndrome Assessment
Mild Signs & Symptoms
Restlessness
Diaphoresis
Tachycardia
Hypertension
Diarrhea
Moderate Signs & Symptoms
Hyperthermia
Decreased Level of Consciousness
Muscle Rigidity
Severe Signs & Symptoms
Seizure and Coma
Treatment
Cyproheptadine
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2 mins

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