Ken Shared "Week 15: Neruology Pharm" - 21 Picmonics
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Week 15: Neruology Pharm
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Indications
- Depression
- Anxiety
- Mechanism of Action
- Selective Serotonin Reuptake Inhibitors
- Drugs
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Side Effects
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
2 mins
Fluoxetine (Prozac)
- Mechanism of Action
- Inhibits Reuptake of Serotonin
- Indications
- Depression
- Side Effects
- Sexual Dysfunction
- CNS Stimulation
- Weight Changes
- Serotonin Syndrome
- Contraindications
- No MAO-Is
- No Anticoagulants / Antiplatelets
- Considerations
- Suicide Risk
- Delayed Onset of Action
2 mins
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Indications
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Mechanism of Action
- Inhibits Reuptake of Serotonin and NE
- Side Effects
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
1 min
Bupropion
- Indications
- Depression
- Smoking Cessation
- Mechanism of Action
- Increase Dopamine and NE
- Side Effects
- Stimulant Side Effects
- Seizure
1 min
Tricyclic Antidepressants (TCAs)
- Mechanism of Action
- Inhibits Reuptake of Norepinephrine and Serotonin
- Indications
- Depression
- Bipolar Disorder
- Fibromyalgia
- Side Effects
- Sedation
- Orthostatic Hypotension
- Anticholinergic Effects
- Cardiac Toxicity
- Considerations
- Delayed Effect
- Do Not Stop Abruptly
2 mins
Tricyclic Antidepressants (TCAs) Indications
- Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- Drugs
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
2 mins
Tricyclic Antidepressant (TCA) Antidote
- Antidote
- Sodium Bicarbonate (NaHCO3)
27 secs
Monoamine Oxidase Inhibitor (MAOI) Contraindications
- Contraindications
- Wine and Cheese
- Hypertensive Crisis
- Serotonin Drugs
- Serotonin Syndrome
1 min
Monoamine Oxidase Inhibitors (MAO-Is)
- Indications
- Atypical Depression
- Mechanism of Action
- Increase Levels of Amine Neurotransmitters
- Drugs
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
1 min
Aripiprazole (Abilify)
- Mechanism
- 2nd Generation Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Disorder
- Depression
- Side Effects
- Headache
- Dizziness
- Nausea and Vomiting
- Insomnia
- Anxiety
- Considerations
- Low Risk of Extrapyramidal Symptoms
- Lowest Risk of Weight Gain
2 mins
Antipsychotics Overview
- Generations
- Typical
- Atypical
- Mechanism
- Blocks D2 Receptor
- 2nd Generation Blocks the 5-HT 2 Receptor
- Indications
- Psychosis
- Delirium
- Bipolar Disorder
- Tourette’s Syndrome
- Side Effects
- Hyperprolactinemia
- Extrapyramidal Symptoms
- Tardive Dyskinesia
- Neuroleptic Malignant Syndrome
4 mins
Low Potency Antipsychotic Drugs
- Drugs
- Chlorpromazine
- Corneal Deposits
- Thioridazine
- Retinal Deposits
- Shared Side Effects
- Alpha1 Antagonist Effects
- Anticholinergic Effects
- Antihistamine Effects
2 mins
High Potency Antipsychotic Drugs
- High Potency Drugs
- Fluphenazine
- Trifluoperazine
- Haloperidol
- Pimozide
- Side Effects
- Extrapyramidal Symptoms
- Short Term
- Dystonia
- Restlessness (Akathisia)
- Torticollis
- Long Term
- Tardive Dyskinesia
- Parkinson's-Like Symptoms
- Neuroleptic Malignant Syndrome
3 mins
Chlorpromazine (Thorazine)
- Mechanism
- Low Potency Antipsychotic
- Indications
- Schizophrenia
- Hiccups
- Side Effects
- Sedation
- Weight Gain
- Orthostatic Hypotension
- Anticholinergic Effects
- QT Prolongation
- Neuroendocrine Effects
- Caution in Seizure Patients
- Corneal Deposits
2 mins
Neuroleptic Malignant Syndrome
- FEVER Acronym
- Fever
- Encephalopathy
- Vital Signs Unstable
- Elevated Enzymes
- Rigidity of muscles
- Reversal Agent
- D2 Agonists
- Bromocriptine
- Dantrolene
2 mins
Atypical Antipsychotics
- Indications
- Schizophrenia
- Mechanism of Action
- Unknown Mechanism
- Side Effects
- Seizures
- Prolonged QT Interval
- Agranulocytosis
- Weight Gain
- Fewer Extrapyramidal Side Effects
- Fewer Anticholinergic Side Effects
2 mins
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
- Autonomic Instability
- Muscle Rigidity
- Malignant Hyperthermia
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Dantrolene
- Neuroleptic Malignant Syndrome
- Antidopaminergic Medications
- Hyporeflexia
- Myoglobinuria
- Dantrolene
- Serotonin Syndrome
- Serotonergic Medications
- Hyperreflexia
- Clonus
- Cyproheptadine
3 mins
Clozapine (Clozaril)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Levodopa-Induced Psychosis
- Side Effects
- Weight Gain
- Hypersalivation (Sialorrhea)
- Myocarditis
- Agranulocytosis
- Sedation
- Orthostatic Hypotension
- Constipation (Risk of Bowel Ileus)
- Considerations
- Weekly Lab Tests
2 mins
Pregabalin (Lyrica)
- Mechanism
- GABA Analog
- Indications
- Seizures
- Neuropathic Pain
- Fibromyalgia
- Side Effects
- Headache
- Dizziness
- Somnolence (Fatigue)
- Weight Gain
- Angioedema
- Rhabdomyolysis
- Considerations
- Dependence
1 min
Risperidone (Risperdal)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Side Effects
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Considerations
- Intramuscular Long Acting (Depot) Form
2 mins
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