United States University Faculty Shared "USU: MSN 571 WEEK 4" - 84 Picmonics
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USU: MSN 571 WEEK 4
NSAIDs
- Indications
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Mechanism of Action
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Side Effects
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
1 min
Aspirin
- Indications
- Fever
- Pain and Headache
- Cardiovascular Disease (CAD)
- Mechanism of Action
- Irreversible inhibition of COX-1 and COX-2
- Suppress Thromboxanes and Prostaglandins
- NSAID
- Side Effects
- Reye's Syndrome
- Tinnitus
- Peptic Ulceration
- Mixed Acidosis/Alkalosis
- Nephropathy
2 mins
Aspirin Poisoning (Salicylism) Assessment
- Early Symptoms
- Nausea and Vomiting
- Tinnitus
- Confusion
- Hyperventilation
- Respiratory Alkalosis
- Late Symptoms
- Metabolic Acidosis
- Coma
- Hyperthermia
1 min
Reye's Syndrome
- Cause
- Aspirin (Salicylates) to Treat Viral Illness (In Children)
- Assessment
- Cerebral Edema
- Lethargy (Decreased LOC)
- Vomiting
- Liver Failure
- Interventions
- Monitor for Increased ICP
- Mannitol (Osmitrol)
- Considerations
- No Aspirin for Children
2 mins
Ibuprofen (Advil, Motrin)
- Mechanisms
- NSAID
- COX Inhibitor
- Indications
- General Pain
- Fever
- Inflammatory Conditions
- Side Effects
- GI Ulcers
- Nephrotoxicity
- Rash
- Considerations
- Avoid with Alcohol
- Risk of Thrombotic Event
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Acetaminophen
- Indications
- Fever
- Pain
- Mechanism of Action
- Reversibly Inhibits COX
- Acts Primarily in CNS
- Side Effect
- Hepatic Necrosis
- N-acetylcysteine Antidote
51 secs
Acetaminophen Antidote
- Antidote
- N-Acetylcysteine
33 secs
Celecoxib
- Indications
- Rheumatoid Arthritis
- Osteoarthritis
- Pain
- Mechanism of Action
- NSAID
- Selectively Inhibits COX-2
- Side Effects
- Sulfa Allergy
- Increased Risk of Thrombosis
- GI Bleed
- Contraindication
- Pregnancy > 30 Weeks
1 min
Cell Surface Proteins - B Cells
- Ig
- CD19
- CD20
- CD21
- CD40
- MHC II
- B7
1 min
Neural Crest Derivatives
- CA MOTEL ASS
- Craniofacial Structures (skull)
- Arachnoid and Pia Mater
- Melanocytes
- Odontoblasts
- Tracheal Cartilage
- Enterochromaffin (Adrenal Medulla)
- Laryngeal Cartilage
- All Ganglia
- Schwann Cells
- Spiral Septum (Aorticopulmonary Septum)
2 mins
Killed (Inactivated) Whole Vaccines
- Characteristics
- Require Booster Shots
- Vaccines
- Mostly Humoral Immune Response
- Polio (Salk)
- Rabies
- Cholera
- Hepatitis A
54 secs
Killed (Inactivated) Fractional Protein Vaccines
- Subunit Vaccines
- Subunit
- Influenza (Intramuscular)
- Bordetella Pertussis
- Hepatitis B
- Human Papillomavirus (HPV)
- Bacillus anthracis (Anthrax)
- Toxoid Vaccines
- Toxoid
- Corynebacterium diphtheriae (Diphtheria)
- Clostridium tetani (Tetanus)
- Considerations
- DTaP and Tdap
3 mins
Live Attenuated Vaccines
- Characteristics
- Humoral and Cellular Immune Response
- May Revert to Virulent Form
- Do Not Require Boosters
- Vaccines
- Varicella (Chickenpox)
- Zoster (Shingles)
- Polio (Sabin)
- Smallpox
- Yellow Fever
- Influenza (Intranasal)
- MMR
- Rotavirus
- Typhoid Fever (Oral)
- BCG (Bacillus Calmette-Guérin)
4 mins
Toxoid Vaccines
- Consist of Toxins Released From a Pathogen
- May Require Boosters
- Safe In Immunocompromised Patients
- Corynebacterium Diphtheriae Vaccine
- Tetanus Vaccine
- Bordetella Pertussis Vaccine
2 mins
Tacrolimus (Prograf) Overview
- Mechanisms
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Transplant Rejection
- Atopic Dermatitis
- Considerations
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
1 min
Tacrolimus (Prograf) Side Effects
- Nephrotoxicity
- Neurotoxicity
- GI Distress
- Infection
- Hypertension
- Hyperkalemia
- Hyperglycemia
1 min
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cyclosporine (Sandimmune) Side Effects
- Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
1 min
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
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