Nicole Shared "PPOM I Lecture 43" - 8 Picmonics
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PPOM I Lecture 43
- Symptoms
- Optic Neuritis
- Internuclear Ophthalmoplegia
- Scanning Speech
- Urinary and Fecal Incontinence
- Motor Issues (Intention Tremor, Paresis)
- Numbness and Pain
- Depression
- Relapsing Symptoms
- Diagnosis
- Gold Standard = Plaques on MRI
- Increased CSF Immunoglobulins (IgG)
- Oligoclonal Bands
- Features
- More Common in Women
- Presents in 20's and 30's
- Northern Europeans
- Mechanism
- Unknown mechanism, genetic factor
- HLA-DRB1
- Autoimmune Demyelination of CNS
- White Matter of Brain and Spinal Cord
- T Cell Mediated Inflammation
- Assessment
- Ascending Paralysis
- Muscle Weakness
- Paresthesias (Pins and Needles)
- Diplopia
- Difficulty Speaking
- Dysphagia
- Labile Blood Pressure
- Loss of Bowel and Bladder Control
- Considerations
- Aggressive Airway Management
- Pathophysiology
- Autosomal Recessive
- Arylsulfatase A Deficiency
- Increased Cerebroside Sulfate
- Signs and Symptoms
- Demyelination
- Ataxia
- Dementia
- Pathophysiology
- Autosomal Recessive
- Galactocerebrosidase Deficiency
- Increased Psychosine
- Signs and Symptoms
- Developmental Delay
- Peripheral Neuropathy
- Optic Atrophy
- Diagnosis
- Globoid Cells
- Pathophysiology
- X-linked Recessive
- Peroxisome Dysfunction
- ABCD1 Mutation
- Presentation
- Adrenal Insufficiency
- Leukoencephalopathy
- Testicular Insufficiency
- Diagnosis
- Increased Very Long-chain Fatty Acids (VLCFA)
- Demyelination
- Genetic Testing
- Treatment
- Lorenzo's Oil
- Hematopoietic Stem Cell Transplantation
- Characteristics
- Non-enveloped
- Double-stranded DNA
- Circular
- Disease
- BK Virus
- Kidney Damage
- JC Virus
- Progressive Multifocal Leukoencephalopathy (PML)
- HIV/AIDS
- Oligodendrocyte
- Demyelination of CNS
- Pathophysiology
- Demyelination of CNS
- Reactivation of JC Virus
- Clinical Features
- Neurologic Deficits
- Seizure
- Vision Changes
- Encephalopathy
- Diagnosis
- Brain MRI or CT
- CD4 Count
- CSF Sample
- Treatment
- Supportive Care
- ART Therapy
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