Anne LaVance Shared "PHAR 104 Pharmacology for the Pharm Tech" - 85 Picmonics

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PHAR 104 Pharmacology for the Pharm Tech

Routes of Administration Part One
Enteral Administration
Oral
Sublingual
Buccal
Rectal
Tubes
Topical or Mucous Membrane Administration
Transdermal
Drops/Spray
Vaginal
Inhalation Administration
Inhalation
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2 mins
Routes of Administration Part Two (Parenteral)
Parenteral Administration
Intradermal
Subcutaneous
Intramuscular (IM)
Intravenous
Epidural
Intrathecal
Intraosseous
Intraperitoneal
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2 mins
Autonomic Nervous System
Characteristics
Sympathetic Nervous System
Fight or Flight
All Preganglionic Neurons Release Acetylcholine
Sympathetic Postganglionic Neurons Release Norepinephrine
Antagonistic Effects of Sympathetic and Parasympathetic Nervous Systems
Parasympathetic Nervous System
Rest and Digest
Parasympathetic Postganglionic Neurons Release Acetylcholine
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2 mins
Benzodiazepines Overview
Indications
First Line for Status Epilepticus
Anesthesia Induction
Anxiety
Eclampsia
Detoxification
Mechanism of Action
'-zepam' and '-zolam" Suffix
Increase Frequency of Cl- Channel Opening
Side Effects
Decrease REM Sleep
CNS Depression
Dependence
Antidote
Flumazenil for Overdose
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2 mins
Diazepam (Valium)
Indications
Anxiety
Seizures and Status Epilepticus
Muscle Spasms
Alcohol Withdrawal
Side Effect/Assessment
Dizziness/Vision Changes
Confusion/Amnesia
Urinary Incontinence
Behavioral Changes
Respiratory Depression
Antidote
Flumazenil (Romazicon)
Nursing Considerations
Fall Precaution
Do Not Stop Abruptly
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2 mins
Triazolam (Halcion)
Mechanism
Rapid-Onset Benzodiazepine
Indications
Insomnia
Side Effects
Rebound Insomnia
Respiratory Depression
Hypotension
Paradoxical Excitement
Amnesia
Confusion
Contraindications
Pregnancy
Considerations
Short-Term Administration
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Benzodiazepine Intoxication Assessment
Drowsiness
Confusion
Respiratory Depression
Hypotension
Coma
Treatment
Flumazenil (Romazicon)
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2 mins
Benzodiazepine Antidote
Antidote
Flumazenil
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39 secs
Nonbenzodiazepine Hypnotics
Indications
Insomnia
Mechanism of Action
Short Half-Life
Acts on BZ1 GABA receptor
Less dependence
Drugs
Zolpidem (Ambien)
Side Effects
Ataxia, confusion
Antidote
Flumazenil for Overdose
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1 min
Zolpidem (Ambien)
Mechanism
Hypnotic
Indications
Insomnia
Side Effects
Daytime Drowsiness
Bizarre Sleep Behaviors
Sleep Driving
Angioedema
Considerations
Short Term Administration
Take Immediately Before Bedtime
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1 min
Buspirone
Indications
Generalized Anxiety
Mechanism of Action
Releases Dopamine and NE
Stimulates 5-HT1A receptors
Side Effects
Low Side Effect Profile
Safer with Alcohol than Other Anxiolytics
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1 min
Buspirone (Buspar)
Mechanism
Increases Serotonin
Indications
Anxiety
Side Effects
Dizziness
Insomnia
Considerations
Delayed Effect
No Alcohol Interaction
No CNS Effects
Low Abuse Potential
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2 mins
Anxiety Assessment
Mild
Increased Alertness
Heightened Perception
Moderate
Perception Narrowed
Short Attention Span
Shaking
Severe
Ineffective Problem Solving
Automatic Behavior
Hyperventilation
Panic
Hallucinations
Inability to Function or Communicate
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2 mins
Types of Seizures
Tonic-clonic
Tonic
Clonic
Absence (Petit Mal)
Myoclonic
Atonic
Partial (Focal) Seizure
Simple Partial
Complex Partial
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2 mins
Seizure Interventions
Maintain Airway
Side-lying Position
Support Head
Move to Floor
Benzodiazepines
Considerations
Never Restrain
No Objects in Mouth
Document Details
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2 mins
Barbiturates
Barb- Drug Names
Indications
Seizure Treatment
Anesthesia Induction
Mechanism of Action
Increased Duration of Cl- Channel Opening
Decrease Neuron Firing
Side Effects
Sedation
Cardiovascular and Respiratory Depression
CNS Depression
P450 inducer
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2 mins
Pregabalin (Lyrica)
Mechanism
GABA Analog
Indications
Seizures
Neuropathic Pain
Fibromyalgia
Side Effects
Headache
Dizziness
Somnolence (Fatigue)
Weight Gain
Angioedema
Rhabdomyolysis
Considerations
Dependence
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1 min
Phenobarbital (Barbiturates)
Mechanism
Barbiturate
Indications
Seizures
Side Effects
Ataxia
Paradoxical Excitement
Fatigue/Drowsiness
Considerations
Monitor Plasma Levels
High Potential for Abuse
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1 min
Phenytoin
Indications
Status Epilepticus
Tonic-Clonic Seizures
Mechanism of Action
Blocks Na+ Channel Activation
Inhibition of Glutamate Release
Class IB Antiarrhythmic
Side Effects
Teratogenic
Macrocytic Megaloblastic Anemia
Induce Cytochrome P450
Drug-induced Lupus
Neuropathy
Hirsutism
Gingival Hyperplasia
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1 min
Carbamazepine
Indications
First-line Seizure Medication
First Line for Trigeminal Neuralgia
Mechanism of Action
Stabilizes Inactive State of Na+ Channels
Side Effects
Stevens-Johnson Syndrome
Induce Cytochrome P450
Teratogen
Hepatotoxicity
Blood Dyscrasias
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2 mins

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