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Biochem Dxs 4
Cystic Fibrosis Mechanisms
CFTR chromosome 7
Cl- channel defect
Decreased chloride secretion
Increased Na and water reabsorption
Increased Na and Cl in sweat
Dehydration of mucous layers
Cystic Fibrosis Diagnosis and Treatment
Sweat Chloride Test > 60 mmol/L
Cystic Fibrosis Symptoms and Complications
Recurrent Pulmonary Infections
Malabsorption and Diarrhea
Chronic Hepatic Disease
Infertility in Males
Von Willebrand Disease
Mixed platelet and coagulation disorder
Autosomal Dominant Condition Leading to Reduced vWF
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