Pencil Villain Shared "Integumentary System" - 23 Picmonics
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Integumentary System
Skin Anatomy
- Characteristics
- Epidermis
- Keratinocytes
- Melanocytes
- Dendritic Cells
- Merkel Cells
- Dermis
- Sweat Glands
- Hair Follicles
- Sebaceous Glands
- Hypodermis
3 mins
Skin Functions
- Characteristics
- Thermoregulation
- Protection
- Innate Immune Protection
- Synthesize Vitamin D
- Water and Salt Excretion
- Dilated Capillaries are a Blood Reservoir
2 mins
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
- Mechanism
- Topical Antimicrobial
- Indications
- Burns
- Open Wound Care
- Side Effects
- Mafenide
- Pain
- Acidosis
- Considerations
- Administer Analgesic Prior to Wound Care
1 min
Squamous Cell Carcinoma of the Skin
- Epidemiology
- 2nd Most Common Skin Cancer
- UV Light Exposure
- Long-term Immunosuppression
- Arsenic Exposure
- Signs/Symptoms
- Ulcerative Red Lesion
- Precursor Actinic Keratosis
- Commonly Lower Lip
- Diagnosis
- Biopsy shows Keratin Pearls
- Treatment
- Mohs Micrographic Surgery
2 mins
Basal Cell Carcinoma of the Skin
- Pathophysiology
- Most Common Skin Cancer
- 2/3 of Cases Due to UV Light Exposure
- Pink, Pearl-like Lesions
- Rolled Borders
- Telangiectasias
- Commonly Upper Lip
- Diagnosis
- Shave Biopsy
- Pallisading Nuclei
- Treatment
- Mohs Micrographic Surgery
2 mins
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
1 min
Melanoma Mechanism and Characteristics
- Mechanism
- Associated with Sunlight Exposure
- Mutation in B-RAF kinase
- Large Number of Moles
- Fair-Skinned People at Higher Risk
- Growth Phases
- Radial Growth Phase
- No Metastasis
- Vertical Growth Phase
- Depth of Tumor Correlates with Risk of Metastasis
1 min
Melanoma Diagnosis
- Signs
- ABCDE Mnemonic
- Asymmetry
- Border irregularity
- Color variation
- Diameter > 6mm
- Evolution over time
- Diagnosis
- S-100 Tumor Marker
- LDH (Lactate Dehydrogenase) Screens for Metastasis
- Treatment
- Wide Local Excision
- Adjuvant Therapy
1 min
Types of Malignant Melanoma
- Superficial Spreading
- Most Common Cause of Melanoma
- Nodular
- Aggressive and Rapidly Arising
- Acral-Lentiginous
- Males
- Asians and African Americans
- Lentigo Maligna
- Geographic Shape
- Sun Exposed Areas
2 mins
Actinic Keratosis
- Sun Exposure
- Papules or Plaques
- Small, Rough
- Erythematous
- Precursor to Squamous Cell Carcinoma
53 secs
Cancer Warning Signs (CAUTION)
- CAUTION
- Change in Bowel or Bladder Habits
- A Sore That Does Not Heal
- Unusual Bleeding or Discharge
- Thickening or Lump in the Breast or Elsewhere
- Dyspepsia (Indigestion)
- Obvious Change to Warts or Moles
- Nagging Cough
1 min
Atopic Dermatitis / Eczema
- Presentation
- Pruritic Vesicles
- Inflammatory Skin Rash
- Cheeks in Children
- Skin Flexural Areas
- Associated with Asthma and Allergic Rhinitis
- Treatment
- Tacrolimus
- Moisturizers
- Corticosteroids
- Phototherapy
- Avoid Triggers
- Antihistamines
2 mins
Vitiligo
- Pathophysiology
- Autoimmune Destruction of Melanocytes
- Presentation
- Hypopigmentation
- Acral Areas and Around Orifices
- Diagnosis
- Clinical Presentation + Woods Lamp
- Risk Factors
- Other Autoimmune Diseases
- Treatment
- Glucocorticoids
- Tacrolimus
- Phototherapy
2 mins
Psoriasis
- Presentation
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Histological Finding
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Treatment
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
2 mins
Lichen Planus
- Pathophysiology
- Mucocutaneous Disorder
- 30-60 year olds
- Signs & Symptoms
- Pruritic
- Plaques or Papules
- Purple & Polygonal
- Often Mucosal or Genital Involvement
- Wickham Striae
- Diagnosis
- Biopsy
- Sawtooth Infiltrate of Lymphocytes
- Treatment
- Topical Corticosteroids
- Considerations
- Hepatitis C Association
2 mins
Erythema Nodosum
- Pathophysiology
- Panniculitis
- Painful Inflammation
- Subcutaneous Fat
- Anterior Shins
- Risk Factors
- Coccidioidomycosis
- Pregnancy or OCP Use
- Crohn's Disease
- Tuberculosis (TB)
- Histoplasmosis
- Sarcoidosis
- Ulcerative Colitis
2 mins
Pityriasis Rosea
- Preceded by Upper Respiratory Tract Infection
- Single "Herald Patch"
- "Christmas Tree" Distribution
- Plaques with Collarette Scale
- Self-resolving in 6-8 Weeks
2 mins
Stevens-Johnson Syndrome
- Etiologies
- Drugs
- Symptoms
- < 10% of Body Surface Area (BSA) Involved
- 10-30% BSA Overlaps with Toxic Epidermal Necrolysis (TEN)
- Fever
- Affects Skin and Mucous Membranes
- Bullae Formation
- Necrosis
- Sloughing of Skin
- High Mortality Rate
- Treatment
- Supportive Care
- IVIG (Intravenous Immunoglobulin)
3 mins
Acanthosis Nigricans
- Associations
- Endocrine Disorders
- Diabetes Mellitus
- Obesity
- Malignancy
- Presentation
- Velvety Plaques
- Dark, Thickened Flexural Areas
- Diagnosis
- Hyperkeratosis with Melanocytes
- Treatment
- Treat Underlying Disorder
2 mins
Pemphigus Vulgaris
- Pathophysiology
- Autoantibodies against desmosomes
- Symptoms
- Flaccid Bullae on Skin
- Oral Mucosa Involvement
- Intraepidermal Acantholysis
- Fluid Loss
- Infection
- Nikolsky Positive
- Diagnosis
- Biopsy showing Autoantibodies
- Treatment
- IVIG and Plasmapheresis
- Oral Steroids
- Immunosuppressants
2 mins
