Alaine Shared "B7 Pharm Exam 3" - 49 Picmonics
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B7 Pharm Exam 3
Acne Vulgaris Presentation and Pathophysiology
- Presentation
- Papules/Comedones in Mild Cases
- Blackheads Open, Whiteheads Closed
- Pustules in Mild-Moderate Cases
- Nodules/Cysts in Severe Cases
- Pathophysiology
- Inflammation at Hair Follicle/Sebaceous Gland
- Increased Androgens
- Colonization by Cutibacterium Acnes
3 mins
Clindamycin
- Mechanism of Action
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Blocks Translocation
- Indications
- Anaerobic Infections above the Diaphragm
- Aspiration Pneumonia
- Lung Abscess
- Side Effects
- Can Cause Pseudomembranous Colitis
1 min
Macrolides
- Mechanism of Action
- Bacteriostatic
- Bind to 23S rRNA of 50S Subunit
- Inhibit Protein Synthesis by Blocking Translocation
- Macrolides
- Erythromycin
- Azithromycin
- Clarithromycin
- Indications
- Gram-Positive Cocci
- Atypical Pneumonia
- Chlamydia
- Considerations
- Resistance by Methylation of 23S rRNA Binding
2 mins
Protein Synthesis Inhibitors
- Drug Names
- 30S inhibitors
- Aminoglycosides
- Tetracyclines
- 50S inhibitors
- Chloramphenicol
- Clindamycin
- Erythromycin
- Lincomycin
- Linezolid
3 mins
Vitamin A (Retinol) Function and Deficiency
- Mechanism
- Retinol
- Constituent of Visual Pigments
- Differentiation of Epithelial Cells into Specialized Tissue
- Signs and Symptoms
- Night Blindness
- Dry Skin
- Considerations
- Used to Treat Measles
- Antioxidant
2 mins
Vitamin A (Retinol) Toxicity
- Signs and Symptoms
- Alopecia
- Vision Changes
- Headache
- Skin Changes
- Hyperlipidemia
- Hepatotoxicity
- Arthralgias
- Teratogen
- Cleft palate
- Cardiac Abnormalities
3 mins
Tetracycline Toxicities
- Inhibition of Bone Growth in Children
- Teratogen
- Discoloration of Teeth
- Photosensitivity
- GI Distress
2 mins
Tetracycline Mechanism
- Binds to 30 S to Prevent Attachment of Aminoacyl tRNA
- Limited CNS Penetration
- Divalent Cations Inhibit Absorption
- Must Not Take with Milk, Antacids, Iron
1 min
Tetracycline Drug Names and Indications
- Drug Names
- Demeclocycline
- Minocycline
- Doxycycline
- Fecally Eliminated
- Can be Used in Renal Failure
- Indications
- Antidiuretic Hormone Antagonist
- Chlamydia
- Rickettsia
- Borrelia burgdorferi
- Helicobacter Pylori
- Mycoplasma Pneumonia
3 mins
Contraception
- Indications
- Preventing Unplanned Pregnancy
- Barrier Methods
- Spermicides
- Diaphragm
- Cervical Cap
- Contraceptive Sponge
- Male Condom
- Hormonal Method
- Oral Contraceptive
- Intrauterine Device (IUD)
- Injectable Progestins
2 mins
Spironolactone (Aldactone)
- Mechanisms
- Inhibition of Aldosterone
- Potassium Retention
- Indications
- Hypertension
- Edema
- Heart Failure
- Side Effects
- Hyperkalemia
- Endocrine Effects
- Consideration
- Avoid Potassium Supplements
2 mins
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Rosacea
- Characteristics
- Episodes Provoked by Alcohol, Heat, or Emotions
- Erythematotelangiectatic Rosacea
- Facial Flushing and Telangiectasias
- Sun Protection
- Topical Brimonidine
- Papulopustular Rosacea
- Papules and Pustules
- Topical Metronidazole
- Phymatous Rosacea
- Rhinophyma
- Laser Ablation
- Considerations
- Avoid Triggers
2 mins
Lice
- Clinical Features
- Pediculosis Capitis, Corporis, Pubis
- Pruritis
- Hyperpigmentation
- Louse-borne Diseases
- Trench Fever
- Bartonella Quintana
- Epidemic Typhus
- Rickettsia Prowazekii
- Relapsing Fever
- Borrelia Recurrentis
- Treatment
- Permethrin
- Malathion
- Ivermectin
3 mins
Scabies
- Pathophysiology
- Sarcoptes Scabiei Mite
- Signs & Symptoms
- Pruritus
- Papules with Burrows
- Webs of Fingers and Toes
- Axilla and Nipples
- Diagnosis
- Skin Scraping
- Dermoscopy
- Mites and Eggs on Magnification
- Treatment
- Permethrin Cream
- Oral Ivermectin
- Lindane Cream
- Considerations
- Wash All Linens In Hot Water
3 mins
Tacrolimus (Prograf) Overview
- Mechanisms
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Transplant Rejection
- Atopic Dermatitis
- Considerations
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
1 min
Tacrolimus (Prograf) Side Effects
- Nephrotoxicity
- Neurotoxicity
- GI Distress
- Infection
- Hypertension
- Hyperkalemia
- Hyperglycemia
1 min
Vitiligo
- Pathophysiology
- Autoimmune Destruction of Melanocytes
- Presentation
- Hypopigmentation
- Acral Areas and Around Orifices
- Diagnosis
- Clinical Presentation + Woods Lamp
- Risk Factors
- Other Autoimmune Diseases
- Treatment
- Glucocorticoids
- Tacrolimus
- Phototherapy
2 mins
Atopic Dermatitis / Eczema
- Presentation
- Pruritic Vesicles
- Inflammatory Skin Rash
- Cheeks in Children
- Skin Flexural Areas
- Associated with Asthma and Allergic Rhinitis
- Treatment
- Tacrolimus
- Moisturizers
- Corticosteroids
- Phototherapy
- Avoid Triggers
- Antihistamines
2 mins
Psoriasis
- Presentation
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Histological Finding
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Treatment
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
2 mins
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