Megha Shared "1/24" - 27 Picmonics

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Subdural Hematoma
Mechanism
Tear of Bridging Veins
Slow Bleeding, Over Time
Imaging
Subdural Space
Crescent-shaped on CT
Crosses Suture Lines
Midline Shift
Causes
Elderly
Whiplash
Shaken Baby Syndrome
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2 mins
Epidural Hematoma
Mechanism
Middle Meningeal Artery Rupture
Temporal Bone Fracture
Hematoma Between Skull And Dura Mater
Transtentorial Herniation
Lucid Interval
Imaging
Lens-shaped On CT
Does Not Cross Suture Lines
Treatment
Craniotomy
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1 min
Subarachnoid Hemorrhage
Bleeding into Subarachnoid Space
Mechanisms
Trauma
Aneurysm Rupture
AVM Rupture
Vasospasm causes Ischemia
Signs & Symptoms
"Worst Headache Of My Life"
Diagnosis
Noncontrast Head CT
Lumbar Puncture
Angiography
Considerations
Surgery
Blood Pressure Control
Intracranial Pressure Control
Nimodipine for Vasospasm Prophylaxis
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3 mins
Krabbe Disease
Pathophysiology
Autosomal Recessive
Galactocerebrosidase Deficiency
Increased Psychosine
Signs and Symptoms
Developmental Delay
Peripheral Neuropathy
Optic Atrophy
Diagnosis
Globoid Cells
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1 min
Metachromatic Leukodystrophy
Pathophysiology
Autosomal Recessive
Arylsulfatase A Deficiency
Increased Cerebroside Sulfate
Signs and Symptoms
Demyelination
Ataxia
Dementia
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1 min
Friedreich's Ataxia
Trinucleotide Repeat
GAA Repeat
Frataxin
Mitochondrial Dysfunction
Autosomal Recessive
Hammertoes
High Arches
Kyphoscoliosis
Lateral Corticospinal Tract
Posterior Column
Spinocerebellar Tract
Type I Diabetes Mellitus
Hypertrophic Cardiomyopathy
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1 min
Multiple Sclerosis Features and Mechanisms
Features
Twice as often in Women
Presents in 20's and 30's
Northern Europeans
Mechanism
Unknown mechanism, genetic factor
HLA-DRB1
Autoimmune Demyelination of CNS
White Matter of Brain and Spinal Cord
T Cell Mediated Inflammation
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2 mins
Multiple Sclerosis Symptoms and Diagnosis
Symptoms
Optic Neuritis
Internuclear Ophthalmoplegia
Scanning Speech
Urinary and Fecal Incontinence
Motor Issues (Intention Tremor, Paresis)
Numbness and Pain
Depression
Relapsing Symptoms
Diagnosis
Gold Standard = Plaques on MRI
Increased CSF Immunoglobulins (IgG)
Oligoclonal Bands
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4 mins
Rubeola Virus
Characteristics
RNA Virus
Paramyxovirus
Signs and Symptoms
Measles
Rash Spreads From Head to Toe
Koplik Spots First
Red Spots with Blue-White Center on Buccal Mucosa
Cough
Coryza
Conjunctivitis
Subacute Sclerosing Panencephalitis
Giant Cell Pneumonia in Immunosuppressed Patients
Warthin-Finkeldey Multinucleated Giant Cells
Treatment
Vitamin A
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3 mins
Huntington's Disease
Pathophysiology
Autosomal Dominant
Trinucleotide Repeat
CAG Repeats
Chromosome 4
Anticipation
Caudate
Decrease of ACh
Decrease of GABA
Signs and Symptoms
Chorea
Dementia
Depression
Glutamate Toxicity
Neuronal Death via NMDA Binding
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3 mins
Glioblastoma Multiforme
Most Common Primary Brain Tumor
Grade 4 Astrocytoma
Can Cross Corpus Callosum
Butterfly Glioma
Pseudo-palisading Tumor Cells
Areas of Necrosis and Hemorrhage
Stain Astrocytes for Glial Fibrillary Acidic Protein (GFAP)
Grave Prognosis
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2 mins
Meningioma
Epidemiology
Most Common Adult Primary Brain Tumor
pathology
Benign
Originate from Arachnoid Villi
Dural Attachment
Parasagittal
Clinical Manifestations
Contralateral Leg Weakness
Seizures
Diagnosis
Psammoma Bodies
Calcifications
Increased Bone Density
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3 mins
Hemangioblastoma
Most often cerebellar
Associated with Von Hippel-Lindau
Retinal Angiomas
Can produce EPO
Secondary polycythemia
Foamy cells
High vascularity
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58 secs
Schwannoma
Characteristics
Acoustic Schwannoma
Cranial Nerve VIII
Cerebellopontine Angle
S100 Positive
Bilateral Schwannoma in Neurofibromatosis Type 2
Tinnitus
Cranial Nerve V
Affects Corneal Reflex
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2 mins
Oligodendroglioma
Slow growing tumor
Frontal lobe
Chicken Wire Pattern
Fried egg appearance
Calcifications
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31 secs
Prolactinoma
Pituitary Adenoma
Galactorrhea
Prolactin Inhibits Gonadotropin Releasing Hormone
Impotence
Amenorrhea
Bitemporal Hemianopsia
Treat with Dopamine
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2 mins
Pilocytic Astrocytoma
Occurs Most Commonly in Kids
Posterior Fossa
Cerebellum
Well Circumscribed
GFAP
Rosenthal Fibers
Eosinophilic Corkscrew Fibers
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1 min
Medulloblastoma
Pathophysiology
Occur in children
Cerebellum
Fourth ventricle
Diagnosis
Small blue cells
Lots of mitotic figures
Homer Wright Rosettes
Perivascular pseudorosettes
Signs and Symptoms
Hydrocephalus
Ataxia
Wide-based Gait
Treatment
Radiosensitive
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3 mins
Ependymoma
Occur in Children
Fourth Ventricle
Hydrocephalus
Perivascular Pseudorosettes
Rod Shaped Blepharoplasts
Cauda Equina in Adults
Poor Prognosis
Neurofibromatosis Type II
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2 mins
Craniopharyngioma
Hypopituitary
Remnants of Rathke's pouch
Tooth-enamel like calcification
Cholesterol crystals
Yellow viscous fluid
Headache
Bitemporal hemianopsia
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1 min

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