Angie Shared "Pharm 1 Week 13 Skin Disorders" - 15 Picmonics
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Pharm 1 Week 13 Skin Disorders
Acne Vulgaris Presentation and Pathophysiology
- Presentation
- Papules/Comedones in Mild Cases
- Blackheads Open, Whiteheads Closed
- Pustules in Mild-Moderate Cases
- Nodules/Cysts in Severe Cases
- Pathophysiology
- Inflammation at Hair Follicle/Sebaceous Gland
- Increased Androgens
- Colonization by Cutibacterium Acnes
3 mins
Psoriasis
- Presentation
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Histological Finding
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Treatment
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
2 mins
Rosacea
- Characteristics
- Episodes Provoked by Alcohol, Heat, or Emotions
- Erythematotelangiectatic Rosacea
- Facial Flushing and Telangiectasias
- Sun Protection
- Topical Brimonidine
- Papulopustular Rosacea
- Papules and Pustules
- Topical Metronidazole
- Phymatous Rosacea
- Rhinophyma
- Laser Ablation
- Considerations
- Avoid Triggers
2 mins
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Scabies
- Pathophysiology
- Sarcoptes Scabiei Mite
- Signs & Symptoms
- Pruritus
- Papules with Burrows
- Webs of Fingers and Toes
- Axilla and Nipples
- Diagnosis
- Skin Scraping
- Dermoscopy
- Mites and Eggs on Magnification
- Treatment
- Permethrin Cream
- Oral Ivermectin
- Lindane Cream
- Considerations
- Wash All Linens In Hot Water
3 mins
Atopic Dermatitis / Eczema
- Presentation
- Pruritic Vesicles
- Inflammatory Skin Rash
- Cheeks in Children
- Skin Flexural Areas
- Associated with Asthma and Allergic Rhinitis
- Treatment
- Tacrolimus
- Moisturizers
- Corticosteroids
- Phototherapy
- Avoid Triggers
- Antihistamines
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Minoxidil (Loniten, Rogaine)
- Mechanism
- Vasodilates Arterioles
- Indications
- Severe Hypertension
- Baldness
- Side Effects
- Reflex Tachycardia
- Blood Volume Expansion
- Hypertrichosis
- Pericardial Effusion
- Rash
- Considerations
- Give with Beta Blocker and Diuretic
2 mins
Opioid Antidote
- Antidote
- Naloxone
29 secs
Antimuscarinic Antidote
- Antidote
- Physostigmine Salicylate
44 secs
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Acetaminophen Antidote
- Antidote
- N-Acetylcysteine
33 secs
Tricyclic Antidepressant (TCA) Antidote
- Antidote
- Sodium Bicarbonate (NaHCO3)
27 secs
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