Kristin Shared "NMSK-A Exam 2" - 23 Picmonics

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NMSK-A Exam 2

Staphylococcus aureus Characteristics
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Positive
Beta-Hemolytic
Protein A Virulence Factor
Inhibits Phagocytosis
MRSA
Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
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2 mins
Staphylococcus aureus Disease
Skin Infections
Impetigo
Abscesses
Exfoliative Toxin
Scalded Skin Syndrome
Toxic Shock Syndrome (TSST 1)
Binds to MHC II and T Cell Receptor
Food Poisoning
Acute Bacterial Endocarditis
Pneumonia
Osteomyelitis
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2 mins
Staphylococcus epidermidis
Characteristics
Cocci
Gram-Positive
Catalase-Positive
Urease-Positive
Coagulase-Negative
Novobiocin-Sensitive
Component of Normal Skin Flora
Infects Prosthetic Devices and IV Catheters
Contaminates Blood Cultures
Produces Adherent Biofilms
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2 mins
Borrelia burgdorferi
Characteristics
Lyme Disease
Spirochete
Dark-field Microscopy
Giemsa Stain
Silver Stain
White-footed Mouse
Ixodes Tick
Babesia
Anaplasmosis
Signs & Symptoms
Flu-like Symptoms
Erythema Migrans
Bulls Eye Rash
Bilateral Bell's Palsy
Conduction Defects
Arthropathy
Treatments
Doxycycline
Ceftriaxone
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3 mins
Methotrexate
Indications
Rheumatoid Arthritis
Cancer
Medical Abortion
Mechanism
Folic Acid Analog
Inhibits Dihydrofolate Reductase
Side Effects
Pulmonary Fibrosis
Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
Macrocytic Anemia
Hepatitis
Teratogenic
Mucositis
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1 min
Cephalosporins Overview
Mechanism of Action
Beta lactam drug
Inhibits cell wall synthesis
Bactericidal
Side Effects
Hypersensitivity reactions
Vitamin K Deficiency
Disulfiram like reaction with Alcohol
Increased Nephrotoxicity of Aminoglycosides
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1 min
1st Generation Cephalosporin
Drug Names
Cefazolin
Cephalexin
Indications (PEcK Mnemonic)
Proteus mirabilis
E. coli
Klebsiella
Gram-Positive Cocci
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1 min
2nd Generation Cephalosporin
Drug Names
Cefoxitin
Cefaclor
Cefuroxime
Indications (PEcK HENS Mnemonic)
Proteus mirabilis
E. coli
Klebsiella
Gram-Positive Cocci
Haemophilus influenzae
Enterobacter
Neisseria
Serratia marcescens
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2 mins
3rd Generation Cephalosporin
Drug Names
Cefotaxime
Ceftriaxone
Cefdinir
Ceftazidime
Pseudomonas
Indications
Serious Gram-Negative Bacteria Resistant to Other Beta-Lactams
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1 min
4th Generation Cephalosporin
Drug Name
Cefepime
Indications
Increased Activity Against Gram-Positive Infections and Pseudomonas
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29 secs
5th Generation Cephalosporin
Mechanism
Beta-Lactam
Indications
Resistant Bacteria
Broad Spectrum Gram-Positive and Gram-Negative
Drugs
Ceftobiprole
Has Pseudomonas Coverage
Ceftaroline
No Pseudomonas Coverage
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1 min
Clindamycin
Mechanism of Action
Bacteriostatic
Binds 50S Ribosomal Subunit
Blocks Translocation
Indications
Anaerobic Infections above the Diaphragm
Aspiration Pneumonia
Lung Abscess
Side Effects
Can Cause Pseudomembranous Colitis
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1 min
Gout Disease
Acute Inflammatory Monoarthritis
Epidemiology
Primarily in Males
Pathophysiology
Precipitation of Monosodium Urate Crystals
Underexcretion of Uric Acid
Overproduction of Uric Acid
Negatively Birefringent, Needle-Shaped
Symptoms
Swollen, Red, Painful Joint
Asymmetric Joint Distribution
Podagra
Tophus
After Large Meal or Alcohol
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2 mins
Gout Treatment
Acute (Acute-angle)
NSAIDs
Glucocorticoids
Colchicine
Impairs Leukocyte Chemotaxis
Chronic Gout (Crone Goat)
Inhibit Xanthine Oxidase
Allopurinol
Febuxostat
Inhibit Reabsorption of Uric Acid
Probenecid
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1 min
Pseudogout
Pathophysiology
> 50 Years Old
Arthritis of Large Joints (Classically the Knee)
Calcium Pyrophosphate Crystals
Diagnosis
Positively Birefringent
Chondrocalcinosis (On X-ray)
Treatment
NSAIDs
Colchicine
Steroids
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1 min
Osteoarthritis
Mechanism
Articular Cartilage Destruction
Biomechanical Stress
Aging
Signs and Symptoms
Asymmetric
Pain Decreases with Rest
Morning Stiffness Under 30 Minutes
Crepitus
DIP and PIP Joints
Treatment
Lifestyle Changes
Acetaminophen or NSAIDs
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1 min
TNF-Alpha Inhibitors Overview
Mechanism
Downregulates pro-inflammatory cytokines
Decreased lymphocyte activation and migration
Granuloma breakdown
Treats
Crohn's Disease
Rheumatoid Arthritis
Juvenile Rheumatoid Arthritis
Psoriasis
Ankylosing spondylitis
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1 min
HLA-B27 Associations
Associations
PAIR Acronym
Psoriatic Arthritis
Ankylosing Spondylitis
Inflammatory Bowel Disease
Reiter's Syndrome
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1 min
Ankylosing Spondylitis
Chronic Inflammatory Arthritis
"Bamboo Spine"
HLA-B27
Uveitis
Aortic Regurgitation
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1 min
Rotator Cuff
External Rotation
Teres Minor
Infraspinatus
Internal Rotation
Subscapularis
Abduction
Supraspinatus
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1 min

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