Jaymes Shared "Resp Final" - 20 Picmonics
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Resp Final
Influenza Virus
- Characteristics
- RNA Virus
- Orthomyxovirus
- Enveloped
- Negative Sense
- 8 Segments
- Helical
- Hemagglutinin for Viral Entry
- Neuraminidase for Virion Release
- Genetic Shift
- Reassortment of genome to cause major change
- Genetic Drift
- Minor Antigenic Mutations
- Considerations
- Reye Syndrome with Aspirin Use
- Guillain-Barre Syndrome
3 mins
Paramyxovirus
- Characteristics
- Enveloped
- RNA Virus
- Helical
- SS Negative Linear
- Nonsegmented
- Surface Fusion Protein Causes Multinucleated Cells
- Presentation
- Measles
- Mumps
- Bronchiolitis in Babies
- Viruses
- Parainfluenza
- Respiratory Syncytial Virus (RSV)
2 mins
Picornavirus
- Characteristics
- Non-enveloped
- RNA Virus
- Icosahedral
- Positive Sense
- A large polypeptide cleaved by proteases
- Viruses
- Rhinovirus
- Poliovirus
- Coxsackievirus
- Hepatitis A Virus
- Echovirus
- Aseptic meningitis
1 min
Coronavirus
- Characteristics
- RNA Virus
- Enveloped
- Helical
- SS Positive Linear
- Symptoms
- Common Cold
- SARS (Severe Acute Respiratory Syndrome)
1 min
Klebsiella Characteristics
- Characteristics
- Gram-Negative
- Bacilli
- Oxidase-Negative
- Intestinal Flora
- Antiphagocytic Virulence Factor
- Polysaccharide Capsule
- Positive Quellung Reaction
- Mucoid Colonies
- Urease-Positive
- Fast Lactose Fermenter
- Pink on MacConkey Agar
2 mins
Moraxella catarrhalis
- Characteristics
- Gram-Negative
- Diplococci
- Oxidase-positive
- Catalase-positive
- Associated Infections
- Otitis Media
- Sinusitis
- Chronic Obstructive Pulmonary Disease (COPD)
- Bronchitis
- Laryngitis
2 mins
Legionella Characteristics
- Characteristics
- Bacillus
- Poor Gram Stain
- Charcoal Yeast with Iron and Cysteine
- Silver Stain
- Water Sources
- Smokers and Heavy Drinkers
- Detect Antigen in Urine
2 mins
Pseudomonas Aeruginosa Characteristics
- Characteristics
- Gram-Negative
- Bacillus
- Aerobic
- Pyocyanin Pigment
- Blue-green Pigment
- Grape like odor
- Non-lactose Fermenting
- Polysaccharide Capsule
- Catalase-Positive
- Oxidase-Positive
- Inactivates Elongation Factor 2
- Exotoxin A
- Endotoxin
- Water sources
3 mins
Burkholderia
- Characteristics
- Gram-Negative
- Bacilli
- Catalase-Positive
- Oxidase Positive
- Non-lactose Fermenting
- Clinical Manifestations
- Pneumonia
- Associations
- Cystic Fibrosis
- Considerations
- Often Multidrug Resistant
- Contraindication
- Contraindication to Undergo Lung Transplantation
1 min
Histoplasmosis
- Fungi
- 2-5 um
- Yeast Cells within Macrophages
- Starling Bird Poop
- Bat Poop
- Caves
- Mississippi and Ohio River Valleys
- Pneumonia
- Caseating Granuloma
- Erythema Nodosum
1 min
Coccidioidomycosis
- Characteristics
- Fungi
- Dimorphic
- Southwest
- After earthquakes
- Spherule
- 20-60 um
- Signs and Symptoms
- Pneumonia
- Meningitis
- Bone Infection
- Skin infections
- Erythema Nodosum
- Granulomatous Inflammation
- Caseous Necrosis
2 mins
Mycobacterium Tuberculosis Characteristics
- Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation TB
- Reactivation in Apex
3 mins
Streptococcus pyogenes Characteristics
- Characteristics
- Group A Streptococci (GAS)
- Gram-Positive
- Cocci
- Beta-Hemolytic
- Catalase-Negative
- Bacitracin-Sensitive
- Hyaluronic Acid Capsule
- Streptolysin O
- DNase
- Streptokinase
- Exotoxin A
- Pyrrolidonyl Arylamidase (PYR) Positive
2 mins
Corynebacterium diphtheriae
- Characteristics
- Gram-Positive
- Bacillus
- Exotoxin
- ADP Ribosylation of Elongation Factor 2
- Beta Prophage
- Lysogeny
- Tellurite Agar
- Chinese Letters
- Metachromatic Blue Red Granules
- Aniline Stains Deeply Methylene Blue
- Signs and Symptoms
- Pseudomembranous Pharyngitis
- Lymphadenopathy
- Myocarditis
- Polyneuritis
3 mins
Bordetella pertussis
- Pathophysiology
- Gram-Negative
- Coccobacillus
- Bordet-Gengou Agar
- ADP Ribosylating AB Toxin
- Inhibits Gi to cause Increase in cAMP
- Signs AND Symptoms
- Lymphocytosis
- Increase in Insulin
- Catarrhal Phase is Infectious Period
- Paroxysmal Phase is Symptomatic Period
- Whooping Cough
- Treatment
- Macrolides
4 mins
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
55 secs
Ethambutol
- Mechanism of Action
- Bacteriostatic
- Blocks Arabinosyltransferase
- Arabinosyltransferase Polymerizes Carbohydrates
- Carbohydrate Polymers Make Mycobacterium TB Cell Wall
- Side Effects
- Red/Green Color Blindness
- Reversible with Drug Discontinuation
40 secs
Pyrazinamide
- INDICATIONS
- Mycobacterium tuberculosis
- MECHANISM
- Pyrazinoic Acid
- Most Efficient at Acidic pH
- Unknown Mechanism
- SIDE EFFECTS
- Gout (Hyperuricemia)
- Liver Toxicity
3 mins
Adenocarcinoma of the Lung
- Characteristics
- Most Common Lung Cancer
- Most Common in Nonsmokers
- Peripheral Location
- KRAS, EGFR, and ALK Mutations
- Diagnosis
- Glandular Pattern
- Often Stains with Mucin
- Clinical Features
- Presents with Hemoptysis
- Clubbing
- Treatment
- Surgical Resection
- Chemotherapy and Radiation
2 mins
Squamous Cell Carcinoma of the Lung
- Characteristics
- Strong Correlation with Smoking
- More Common in Men
- Central Location
- Cavitating Lesion Extending to Hilum
- PTHrP Causes Hypercalcemia
- Diagnosis
- Keratin Pearls
- Intercellular Bridges
- Treatment
- Surgical Resection (if Early Stage)
- Chemotherapy and Radiation (if Later Stage)
2 mins
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