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Increase Intestinal and Bladder Sphincter Muscle Contraction
Alpha 2 Receptor
Decrease Sympathetic Outflow
Decrease Insulin Release
Increase Platelet Aggregation
Decrease Aqueous Humor Production
Anaphylaxis and Asthma
Alpha-2 Agonists (Sympathoplegics)
Mechanism of Action
Centrally acting Alpha-2 Agonist
Coombs (+) Hemolytic Anemia
SLE Like Syndrome
Alveolar Gas Equation
Partial Pressure of Alveolar Oxygen (PAO2)
Partial Pressure of Oxygen in the Inspired Air (PIO2)
PIO2 Normally Approximated = 150 mmHg
Arterial Partial Pressure of CO2 (PaCO2)
Respiratory Quotient (R)
R Normally Approximated = 0.8
PAO2 = PIO2 - (PaCO2/R)
Angiotensin Receptor Blockers (ARBs)
Mechanism of Action
Angiotensin II Receptor Blockers
Decrease bladder spasms
Mydriasis and Cycloplegia
Reduces Airway Secretions
Asthma and C.O.P.D
Irritable Bowel Syndrome
Wide Pulse Pressure
Water Hammer Pulse
Pulsating Nail Bed
Can Cause Austin Flint Murmur
Bicuspid Aortic Valve
Radiates to Carotids and Apex
Pulsus Parvus et Tardus
Obstructive lung disease
History of Atopic Disease
Hypertrophy of smooth muscle
Charcot Leyden crystals
Initially decreased PaCO2
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