Swanseastephen91 Shared "Bugs" - 101 Picmonics

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Bugs

Actinomyces Israelii
Characteristics
Gram-Positive
Bacillus
Anaerobe
Branching
Oral Flora
Dental Work
Oral Trauma
Associated with IUDs
Signs and Symptoms
GU Infections
Draining Sinus Tract
Facial Abscess
Yellow Sulfur Granules
Treatment
Penicillin
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2 mins
Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
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1 min
Bacillus Anthracis (Anthrax) Characteristics
Characteristics
Gram-Positive
Spore-Forming
D-glutamate Polypeptide Capsule
Protective Antigen
Lethal Toxin
Edema Factor
Increased cAMP
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1 min
Bacillus Anthracis (Anthrax) Disease
Signs and Symptoms
Cutaneous
Painless Black Eschar (Necrotic Lesion)
Pulmonary
Mediastinal Widening
Rapidly Fatal
Woolsorter's Disease
Gastrointestinal
Consuming Anthrax-infected Meat
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2 mins
Bacillus Cereus Characteristics
Gram-Positive
Bacilli
Endospore Forming
B Hemolytic
Toxins and Enterotoxins
Reheated Rice
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1 min
Bacillus Cereus Disease
Signs and Symptoms
Emetic Form
Short Incubation (1-6 Hours)
Nausea and Vomiting
Diarrheal Form
Long Incubation (8-16 Hours)
Diarrhea and GI Pain
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2 mins
Clostridium botulinum
Characteristics
Bacillus
Gram-Positive
Anaerobe
Spore-Forming
Heat Labile Toxin
Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
Canned Food in Adults
Spores in Honey
Signs and Symptoms
Descending Flaccid Paralysis
Diplopia
Ptosis
Floppy Baby
Constipation
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2 mins
Clostridium difficile
Characteristics
Gram-Positive
Bacillus
Anaerobe
Clindamycin and Ampicillin
Toxin A Enterotoxin
Damages Brush Border of Gut
Toxin B Cytotoxin
Damages Cytoskeletal Structure
Signs and Symptoms
Diarrhea
Pseudomembranous Colitis
Toxic Megacolon
Diagnosis
Detect Toxins in Stool
Treatment
Metronidazole
Vancomycin
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3 mins
Clostridium perfringens
Characteristics
Gram-Positive
Bacillus
Anaerobe
Spore-Forming
Alpha Toxin Lecithinase
Phospholipase
Heat Labile Enterotoxin
Signs and Symptoms
Myonecrosis
Gas Gangrene
Food Poisoning and Diarrhea
Treatment
Hyperbaric O2 Chamber
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2 mins
Clostridium tetani
Characteristics
Gram-Positive
Bacilli
Obligate Anaerobic
Exotoxin
Spore-Forming
Renshaw Cells in the Spinal Cord
Blocks Glycine and GABA Release
Signs and Symptoms
Spasms
Risus Sardonicus
Lockjaw
Opisthotonus
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3 mins
Flucytosine
Indications
Cryptococcus
Candida
Used in Combination with Amphotericin B or Azoles
Mechanism
Inhibits DNA and RNA Synthesis
Converted to 5-FU by Cytosine Deaminase
Side Effects
Bone Marrow Suppression
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1 min
Naegleria Fowleri
Pathophysiology
Protozoa
Rapidly Fatal Meningoencephalitis
Swimming in Freshwater Lakes
Travels through Cribriform Plate
Diagnosis
Amoebas in CSF
Treatment
Amphotericin B
Death is Still Common
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1 min
Nocardia
Characteristics
Aerobic
Gram-Positive
Catalase-Positive
Urease-Positive
Acid Fast
Branching
Beaded Filament
AIDS/Immunocompromised
Soil
Signs and Symptoms
Lung Cavitation
Brain Abscess
Kidney Abscess
Treatment
TMP-SMX
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2 mins
Trimethoprim
Mechanism of Action
Bacteriostatic
Inhibits Bacterial Dihydrofolate Reductase
Causes Sequential Block of Folate Synthesis
Used in Combination with Sulfamethoxazole
Combination Used For Recurrent Urinary Tract Infections
Indications
Shigella
Salmonella
Pneumocystis Jiroveci Pneumonia
Side Effects
Decrease in Red and White Blood Cells
Alleviated with Leucovorin Rescue
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2 mins
Aspergillus fumigatus
Characteristics
Fungi
Monomorphic
Septate Hyphae
Branch at Acute Angles
Fruiting Bodies
Disease
Allergic Bronchopulmonary Aspergillosis (ABPA)
Eosinophilia
Increased IgE
Glucocorticoids +/- Azoles
Pulmonary Aspergillosis
TB Cavity
Lung Aspergilloma
Hemoptysis
Invasive Aspergillosis
AIDS/Immunocompromised
Chronic Granulomatous Disease
Hemorrhagic Infarction
Necrotizing Bronchopneumonia
Voriconazole +/- Caspofungin
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3 mins
Candida Albicans
Fungi
Yeast with Pseudohyphae at 20 Degrees C
Germ Tube Formation at 37 Degrees C
Pruritic Vaginitis
White Cottage Cheese Discharge
Fiery Red Mucosa
Diabetics
Antibiotic Use
Esophageal Thrush in Immunocompromised
Diaper Rash
Endocarditis in IV Drug Users
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2 mins
Mucor and Rhizopus
Characteristics
Fungi
Irregular Non-septate Hyphae
Branching Wide Angles over 90 degrees
Signs and Symptoms
Leukemic Patients
Proliferate due to excess ketones and glucose
Diabetic Ketoacidosis (DKA)
Rhinocerebral frontal lobe abscess
Penetrate cribriform plate into brain
Black Necrotic Eschars on Face
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2 mins
Trypanosoma cruzi
Pathophysiology
Protozoa
Triatomine Bug
Kissing bug
Painless bite
Predominantly in South America
Symptoms
Chagas disease
Romana's sign
Dilated Cardiomyopathy
Megacolon
Megaesophagus
Diagnosis
Blood smear
Treatment
Nifurtimox
Benznidazole
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2 mins
Trypanosoma Brucei
Characteristics
Protozoa
Trypanosoma Gambiense
Trypanosoma Rhodesiense
Tsetse Fly
Disease
Painful Bite
African Sleeping Sickness
Recurring Fever
Due to Antigenic Variation
Enlarged Lymph Nodes
Encephalitis
Treatment
Suramin for Blood-Borne Disease
Melarsoprol for CNS Penetration
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2 mins
Syphilis
Characteristics
Treponema pallidum
Spirochete with characteristic motility
Signs and Symptoms
Painless chancre
Condylomata lata
Generalized lymphadenopathy
Rash on palms and soles
Aortitis
Gummas
Neurosyphilis
Argyll Robertson pupils
Vasa vasorum
Tabes dorsalis
Treatment
Penicillin
Jarisch-Herxheimer reaction
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2 mins

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