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Systemic Lupus Erythematosus (SLE) Diagnosis and Clinical Features
IM DAMN SHARP acronym
Systemic Lupus Erythematosus (SLE) Mechanism, Treatment and Complications
Mechanism and Characteristics
Systemic Autoimmune Disease
9:1 female to male ratio
Secondary Antiphospholipid Antibody Syndrome
Hypersensitivity Type IV
T Cell Mediated
PPD Skin Test
Autoantibodies against desmosomes
Flaccid Bullae on Skin
Oral Mucosa Involvement
Biopsy showing Autoantibodies
IVIG and Plasmapheresis
Multiple Sclerosis Features and Mechanisms
Twice as often in Women
Presents in 20's and 30's
Unknown mechanism, genetic factor
Autoimmune Demyelination of CNS
White Matter of Brain and Spinal Cord
T Cell Mediated Inflammation
Multiple Sclerosis Symptoms and Diagnosis
Urinary and Fecal Incontinence
Motor Issues (Intention Tremor, Paresis)
Numbness and Pain
Gold Standard = Plaques on MRI
Increased CSF Immunoglobulins (IgG)
Guillain-Barre Syndrome Assessment
Paresthesias (Pins and Needles)
Labile Blood Pressure
Loss of Bowel and Bladder Control
Aggressive Airway Management
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