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S1 DMSK Week 1
Staphylococcus saprophyticus
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Negative
Novobiocin-Resistant
Urease-Positive
Disease
Urinary Tract Infections (UTI's)
1 min
Staphylococcus epidermidis
Characteristics
Cocci
Gram-Positive
Catalase-Positive
Urease-Positive
Coagulase-Negative
Novobiocin-Sensitive
Component of Normal Skin Flora
Infects Prosthetic Devices and IV Catheters
Contaminates Blood Cultures
Produces Adherent Biofilms
2 mins
Corynebacterium diphtheriae
Characteristics
Gram-Positive
Bacillus
Exotoxin
ADP Ribosylation of Elongation Factor 2
Beta Prophage
Lysogeny
Tellurite Agar
Chinese Letters
Metachromatic Blue Red Granules
Aniline Stains Deeply Methylene Blue
Signs and Symptoms
Pseudomembranous Pharyngitis
Lymphadenopathy
Myocarditis
Polyneuritis
3 mins
Neisseria Meningitidis
Characteristics
Gram-Negative
Diplococci
Chocolate Agar
Thayer-Martin Media
VPN
Oxidase-Positive
Maltose Fermentation
Glucose Fermentation
Endotoxin
Lipooligosaccharide (LOS) in Membrane
Polysaccharide Capsule
IgA Protease
Disease
Waterhouse Friderichsen Syndrome
Adrenal Insufficiency
Petechial Rash
Treatments
Ceftriaxone
Rifampin Prophylaxis
5 mins
Rubeola Virus
Characteristics
RNA Virus
Paramyxovirus
Signs and Symptoms
Measles
Rash Spreads From Head to Toe
Koplik Spots First
Red Spots with Blue-White Center on Buccal Mucosa
Cough
Coryza
Conjunctivitis
Subacute Sclerosing Panencephalitis
Giant Cell Pneumonia in Immunosuppressed Patients
Warthin-Finkeldey Multinucleated Giant Cells
Treatment
Vitamin A
3 mins
Rubeola (Measles)
Mechanism
Virus
Signs and Symptoms
Fever
Red Maculopapular Rash
3 C's
Photophobia
Koplik Spots
Considerations
MMR Vaccination
Antipyretics
Vitamin A Supplementation
2 mins
Rickettsia
Need CoA and NAD
Rocky Mountain spotted fever
Typhus
Ehrlichiosis
Q fever
Arthropod vector
Fever
Headache
Rash
Weil-Felix reaction
Treatment doxycycline
1 min
Rocky Mountain Spotted Fever
Rickettsia rickettsii
Dermacentor Wood Tick
Endemic to East Coast
Fever
Headache
Rash Starts on Wrist and Ankle
Rash migrates towards the trunk
Thrombocytopenia
Hyponatremia
Elevated liver enzymes
59 secs
Disseminated Intravascular Coagulation (DIC)
Pathophysiology
Bleeding State
Activation of Clotting Factors
Deficiency of Clotting Factors
Causes
Sepsis
Trauma
Obstetric Complications
Acute Pancreatitis
Malignancy
Nephrotic Syndrome
Transfusion
2 mins
Syphilis
Characteristics
Treponema pallidum
Spirochete with characteristic motility
Signs and Symptoms
Painless chancre
Condylomata lata
Generalized lymphadenopathy
Rash on palms and soles
Aortitis
Gummas
Neurosyphilis
Argyll Robertson pupils
Vasa vasorum
Tabes dorsalis
Treatment
Penicillin
Jarisch-Herxheimer reaction
2 mins
Paramyxovirus
Characteristics
Enveloped
RNA Virus
Helical
SS Negative Linear
Nonsegmented
Surface Fusion Protein Causes Multinucleated Cells
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