Chiamaka Shared "Clin Med/ Path 2" - 52 Picmonics
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Clin Med/ Path 2
Celiac Disease Characteristics
- Epidemiology
- European Descent
- HLA-DQ2
- HLA-DQ8
- Pathophysiology
- Autoimmune-mediated Intolerance of Gliadin
- Symptoms
- Dermatitis Herpetiformis
- Weight Loss
- Failure to Thrive
- Decreased Bone Density
- Steatorrhea
- Anemia
2 mins
Celiac Disease Diagnosis and Treatment
- Diagnosis
- Blunting of Intestinal Villi
- Lymphocytes in Lamina Propria
- Anti-gliadin Antibodies (IgA)
- Anti-endomysial Antibodies (IgA)
- Anti-tissue Transglutaminase Antibodies (IgA)
- Treatment
- Gluten-Free Diet
- Corticosteroids
- Dapsone
- Complications
- Intestinal Lymphoma
2 mins
Crohn's Disease Assessment
- Diarrhea
- 5-6 per day
- Cramping Abdominal Pain
- Fever
- Weight Loss
- Malabsorption
- Anemia
- Complications
- Obstruction
- Fistulas
2 mins
Crohn's Symptoms and Associations
- Diarrhea
- Malabsorption
- Bile-Wasting
- Pigment Gallstones
- Oxalate Kidney Stones
- Ankylosing Spondylitis
- Erythema Nodosum
- Uveitis
- Migratory Polyarthritis
2 mins
Crohn's Disease Characteristics
- Terminal Ileum and Colon
- Rectal Sparing
- Transmural Inflammation
- Granulomas
- Skip Lesions
- Cobblestone Mucosa
- Fissures
- Fistulas
- Perianal Disease
- Creeping Fat
- Lymphoid Aggregates
- String Sign on Barium Swallow
2 mins
Ulcerative Colitis & Crohn’s Disease
- 5-aminosalicylic (5-ASA) compounds
- Sulfasalazine
- Mesalamine
- Olsalazine
- Corticosteroids
- Corticosteroids
- Prednisone (Glucocorticoids) - oral
- Methylprednisone (Solu-medrol) - parenteral
- Hydrocortisone - parenteral/topical
- Immunosuppressants (Crohn's Disease)
- Azathioprine (Imuran)
- Prodrug of 6-mercaptopurine (6-MP)
- Methotrexate
- Cyclosporine (Sandimmune) Overview
- Antibodies (biologics)
- Infliximab
- Etanercept
- Adalimumab
- Certolizumab
Treatment of UC and Crohns
- 5-asa or sulfasalazine
- budes
- Prodrug of 6-mercaptopurine (6-MP)
- Surgery
Ulcerative Colitis Characteristics
- Autoimmune
- Mucosal and Submucosal Only
- Rectal Involvement
- Stepwise Lesions
- Friable Pseudopolyp
- Crypt Abscess
- Loss of Haustra
- Lead Pipe Appearance
- Bloody Diarrhea
2 mins
Ulcerative Colitis Associations
- Associations
- Toxic Megacolon
- Colorectal Carcinoma
- Anterior Uveitis
- Pyoderma Gangrenosum
- Ankylosing Spondylitis
- Primary Sclerosing Cholangitis
- P-ANCA
1 min
Diverticulosis and Diverticulitis Assessment
- Diverticulosis
- Outpouching
- Diverticulitis
- Inflamed Diverticula
- Assessment
- Abdominal Pain
- Abdominal Distention
- Flatulence
- Fever
- Rectal Bleeding
- Alternating Constipation and Diarrhea
- Considerations
- Peritonitis
2 mins
Diverticulosis and Diverticulitis Interventions
- Interventions
- High Fiber Diet
- Reduce Intra-abdominal Pressure
- Stool Softeners
- Exercise
- Anticholinergics
- Considerations
- Antibiotics
- Bowel Resection
2 mins
Appendicitis
- Mechanism and Characteristics
- Fecalith leading to obstruction and infection
- Most commonly affects teenagers
- Presentation
- Initial peri-umbilical visceral pain
- Subsequent somatic right lower quadrant pain
- Diagnosis
- Rebound tenderness
- Positive psoas sign
- Pain at McBurney's point
- Leukocytosis
- Fever
- Treatment
- Appendectomy
1 min
Acute Appendicitis Treatment
- Diagnosis
- CT Scan
- Treatment
- Immediate Appendectomy
- NPO
- IV Fluids
- Antibiotics
- Perforation
- Tertiary Intention
- Antibiotics Until Afebrile
2 mins
Colorectal Cancer Assessment
- 3rd Most Common Cancer
- Assessment
- Change in Bowel Habits
- Bowel Obstruction
- Rectal Bleeding
- Anemia
- Weight Loss
- Ascites
- Considerations
- Colonoscopy
- FOBT and FIT
2 mins
Irritable Bowel Syndrome (IBS) Assessment
- Abdominal Pain
- Relieved by Defecation
- Alternating Diarrhea and Constipation
- Fatigue
- Excessive Flatulence
- Sensation of Incomplete Evacuation
- Considerations
- Stressors
- Food Intolerances
- More Common in Women
- Rule Out Other Disorders
2 mins
Irritable Bowel Syndrome (IBS) Interventions
- Interventions
- Identify Triggers
- Increase Fiber Intake
- Probiotics
- Anticholinergics
- Tricyclic Antidepressants (TCAs)
- Loperamide
- Linaclotide
- Medications for Women
- Tegaserod (Zelnorm)
- Lubiprostone (Amitiza)
- Alosetron (Lotronex)
2 mins
Intestinal Obstruction
- Partial/Early Obstruction
- Severe Abdominal Pain
- Vomiting
- High Pitched Bowel Sounds
- Abdominal Distention
- Increased Peristalsis
- Total/Neurogenic Obstruction
- Absent Bowel Sounds
- Paralytic Ileus
1 min
Mesenteric Ischemia
- Signs and Symptoms
- Severe Abdominal Pain
- Bloody Diarrhea
- Metabolic Acidosis
- Diagnosis
- Increased WBC
- Increased Lactate (Lactic Acid)
- X-ray
- Air Within Bowel Wall
- CT Angiography
- Bowel Wall Edema
- Treatment
- Antibiotics
- Emergent Surgical Intervention
2 mins
Types of Hernias
- Hiatal
- Gastroesophageal Reflux Disease (GERD)
- Inguinal
- Men
- Femoral
- Women
- Incisional
- Umbilical
- Consideration
- Strangulation
1 min
Intussusception
- Pathophysiology
- Telescoping of Bowel Segments
- Lead Point
- Assessment
- Episodic Abdominal Pain
- Diarrhea
- Sausage-Shaped Mass
- Red Currant Jelly Stools
- Diagnosis
- Ultrasound/CT
- Target Sign
- Considerations
- More Common in Children
- Rotavirus Vaccine Contraindicated
- Management
- Air or Hydrostatic Enema
- Surgical Reduction
3 mins
