Matthew Shared "Derm 1" - 34 Picmonics
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Derm 1
Pemphigus Vulgaris
- Pathophysiology
- Autoantibodies against desmosomes
- Symptoms
- Flaccid Bullae on Skin
- Oral Mucosa Involvement
- Intraepidermal Acantholysis
- Fluid Loss
- Infection
- Nikolsky Positive
- Diagnosis
- Biopsy showing Autoantibodies
- Treatment
- IVIG and Plasmapheresis
- Oral Steroids
- Immunosuppressants
2 mins
Bullous Pemphigoid
- Linear Deposits of IgG
- Affects Hemidesmosomes
- Epidermal Basement Membrane
- Tense Blisters on Skin
- Nikolsky Negative
- Contain Eosinophils
- Rarely Affect Oral Mucosa
2 mins
Vitiligo
- Pathophysiology
- Autoimmune Destruction of Melanocytes
- Presentation
- Hypopigmentation
- Acral Areas and Around Orifices
- Diagnosis
- Clinical Presentation + Woods Lamp
- Risk Factors
- Other Autoimmune Diseases
- Treatment
- Glucocorticoids
- Tacrolimus
- Phototherapy
2 mins
Necrotizing Fasciitis Diagnosis and Treatment
- Diagnosis/Workup
- Usually a Clinical Diagnosis
- Soft Tissue Gas On CT
- Management
- Emergent Surgical Debridement
- Vasopressors and Fluids
- IV Immune Globulin If Strep Toxic Shock Syndrome
- Antibiotic Regimen
- Carbapenem Or Piperacillin-Tazobactam
- PLUS Clindamycin
- PLUS MRSA Coverage
4 mins
Necrotizing Fasciitis Pathophysiology and Characteristics
- Bacterial Infection of Muscle Fascia and Subcutaneous Fat
- Polymicrobial or Monomicrobial
- Polymicrobial: Anaerobe + Gram Negative Enterobacteriaceae
- Monomicrobial: Group A Streptococcus or Staph Aureus
- Clinical Manifestations
- Edema Extending Beyond Erythema
- Crepitus
- Pain Out of Proportion (POOP)
- Anesthesia Over Affected Area (Late Finding)
5 mins
Streptococcus pyogenes Characteristics
- Characteristics
- Group A Streptococci (GAS)
- Gram-Positive
- Cocci
- Beta-Hemolytic
- Catalase-Negative
- Bacitracin-Sensitive
- Hyaluronic Acid Capsule
- Streptolysin O
- DNase
- Streptokinase
- Exotoxin A
- Pyrrolidonyl Arylamidase (PYR) Positive
2 mins
Streptococcus Pyogenes Disease
- Pyogenic
- Pyogenic
- Pyogenic Pharyngitis
- Impetigo
- Cellulitis
- Toxigenic
- Toxic Shock-Like Syndrome
- Scarlet Fever
- Sandpaper Rash
- Strawberry Tongue
- Immunologic
- Immunologic
- Rheumatic Fever
- Antibodies to M Protein
- Acute Glomerulonephritis (Post Streptococcal Glomerulonephritis)
2 mins
Staphylococcus aureus Characteristics
- Characteristics
- Gram-Positive
- Cocci
- Catalase-Positive
- Coagulase-Positive
- Beta-Hemolytic
- Protein A Virulence Factor
- Inhibits Phagocytosis
- MRSA
- Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
2 mins
Staphylococcus aureus Disease
- Skin Infections
- Impetigo
- Abscesses
- Exfoliative Toxin
- Scalded Skin Syndrome
- Toxic Shock Syndrome (TSST 1)
- Binds to MHC II and T Cell Receptor
- Food Poisoning
- Acute Bacterial Endocarditis
- Pneumonia
- Osteomyelitis
2 mins
Atopic Dermatitis / Eczema
- Presentation
- Pruritic Vesicles
- Inflammatory Skin Rash
- Cheeks in Children
- Skin Flexural Areas
- Associated with Asthma and Allergic Rhinitis
- Treatment
- Tacrolimus
- Moisturizers
- Corticosteroids
- Phototherapy
- Avoid Triggers
- Antihistamines
2 mins
Psoriasis
- Presentation
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Histological Finding
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Treatment
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
2 mins
Anti-desmoglein Antibodies
- Pemphigus Vulgaris
- Flaccid Blisters
- Skin and Oral Mucosa
- Positive Nikolsky's Sign
59 secs
Actinic Keratosis
- Sun Exposure
- Papules or Plaques
- Small, Rough
- Erythematous
- Precursor to Squamous Cell Carcinoma
53 secs
Acne Vulgaris Presentation and Pathophysiology
- Presentation
- Papules/Comedones in Mild Cases
- Blackheads Open, Whiteheads Closed
- Pustules in Mild-Moderate Cases
- Nodules/Cysts in Severe Cases
- Pathophysiology
- Inflammation at Hair Follicle/Sebaceous Gland
- Increased Androgens
- Colonization by Cutibacterium Acnes
3 mins
Tinea (Dermatophytes): General Characteristics And Management
- Fungal Cutaneous Infection
- Organisms
- Trichophyton
- Microsporum
- Epidermophyton
- Clinical Features
- Pruritic Rash
- Segmented Hyphae On KOH
- Management
- Topical Azole
- Terbinafine For Tinea Unguium (Nails)
2 mins
Skin Assessment
- Inspect the skin
- Observe for Abnormal Skin Pigmentation
- Inspect for Cyanosis
- Observe Skin for Pallor
- Observe for Jaundice
- Inspect for Erythema
- Palpate the Skin
- Check the Temperature
- Observe the Skin for Moisture
- Inspect for Diaphoresis or Dehydration
- Check skin for edema
- Imprint Thumb Firmly for 3 to 4 Seconds
- Look for lesions
- Note the Characteristics
- Palpate Lesion
4 mins
Rosacea
- Characteristics
- Episodes Provoked by Alcohol, Heat, or Emotions
- Erythematotelangiectatic Rosacea
- Facial Flushing and Telangiectasias
- Sun Protection
- Topical Brimonidine
- Papulopustular Rosacea
- Papules and Pustules
- Topical Metronidazole
- Phymatous Rosacea
- Rhinophyma
- Laser Ablation
- Considerations
- Avoid Triggers
2 mins
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Complications
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
2 mins
TNF-Alpha Inhibitors Overview
- Mechanism
- Downregulates Pro-inflammatory Cytokines
- Decreased Lymphocyte Activation and Migration
- Granuloma Breakdown
- Treats
- Crohn's Disease
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
- Psoriasis
- Ankylosing Spondylitis
1 min
Staphylococcus epidermidis
- Characteristics
- Cocci
- Gram-Positive
- Catalase-Positive
- Urease-Positive
- Coagulase-Negative
- Novobiocin-Sensitive
- Component of Normal Skin Flora
- Infects Prosthetic Devices and IV Catheters
- Contaminates Blood Cultures
- Produces Adherent Biofilms
2 mins
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