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Shehrammajid2889 Shared "Pharm Block 1" - 73 Picmonics

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Pharm Block 1

Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
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1 min
Alpha 2 Receptor
Characteristics
Gi Subunit
Decrease Sympathetic Outflow
Decrease Insulin Release
Decrease Lipolysis
Increase Platelet Aggregation
Decrease Aqueous Humor Production
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2 mins
Beta-1 Receptor
Characteristics
Gs Protein Class
Increased Heart Rate
Increased Contractility
Increase Renin Release
Increased Lipolysis
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44 secs
Beta-2 Receptor
Characteristics
Gs Protein Class
Cardiopulmonary
Increased Heart Rate
Increased Contractility
Bronchodilation
Metabolic
Increased Lipolysis
Increased Insulin
Increased Glycogenolysis
Increased Cellular Potassium Uptake
Considerations
Increased Aqueous Humor Production
Vasodilation
Decrease Uterine Tone
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2 mins
Indirect Cholinomimetics
Acetylcholinesterase Inhibitors
Doesn't Cross BBB
Edrophonium
Myasthenia Gravis (Diagnosis)
Pyridostigmine and Neostigmine
Myasthenia Gravis (Tx)
Ileus
Crosses BBB
Physostigmine
Atropine Overdose
Glaucoma
Donepezil
Alzheimer's
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2 mins
Nondepolarizing Neuromuscular Blocking Drugs
Names Include "Cur"
Competitive Antagonists
Acetylcholine Competition
Reversal of Blockade
Neostigmine, Edrophonium
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1 min
Direct Cholinomimetics
Muscarinic Agonists
Bethanechol
Bladder and Bowels
Methacholine
Bronchoconstriction
Pilocarpine
Contracts Ciliary Muscle and Pupillary Sphincter
Carbachol
Releases Intraocular Pressure
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1 min
Open-Angle Glaucoma
Humor Has Access to Trabecular Meshwork
Presentation
Painless
African American
Elderly
Positive Family History
Primary Open-Angle Glaucoma
Most Common Form of Glaucoma
Unknown Mechanism
Secondary Open-Angle Glaucoma
Blocked Trabecular Meshwork (With Open-Angle)
WBCs
Red Blood Cells (RBC)
Retinal Products
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2 mins
Closed-Angle Glaucoma
Primary
Lens causes pupillary obstruction
Aqueous humor builds behind iris
Iris bends forward, obstructing trabecular mesh
Secondary
Hypoxia Causes Neovascular Proliferation
Contraction and obstruction of trabecular mesh
Chronic disease (Crone)
Asymptomatic
Acute Disease
Eye pain and blindness
Rock-hard eye
Headache
Emergency
Epinephrine contraindicated
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2 mins
Antimuscarinic Antidote
Antidote
Physostigmine Salicylate
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44 secs
Acetylcholinesterase Inhibitor Poisoning
DUMBBELSS
Diarrhea
Urination
Miosis
Bronchospasm
Bradycardia
Emesis
Lacrimation
Salivation
Sweating
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2 mins
Anticholinergics
B.O.AT.S Acronym
Benztropine
Parkinson's Disease
Oxybutynin
Decrease bladder spasms
Atropine
Mydriasis and Cycloplegia
Scopolamine
Motion Sickness
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1 min
Atropine
Indications
Blocks DUMBBeLSS
Bradycardia
Side Effects
Skin Flushing
Increased Temperature
Dry Mouth
Cycloplegia
Disorientation
Mydriasis
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1 min
Acetylcholinesterase Inhibitor Antidote
Antidote
Atropine
Pralidoxime
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1 min
Anticholinergics Continued
Drugs
Glycopyrrolate
Reduces Airway Secretions
Ulcer Treatment
Ipratropium
Asthma and C.O.P.D
Dicyclomine
Hyoscyamine
Irritable Bowel Syndrome
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1 min
Succinylcholine
Indications
Inducing Paralysis
Mechanism of Action
Neuromuscular Blocking Drugs
Motor Nicotinic Receptor
ACh Receptor Agonist
Depolarization
Phases of Action
Phase I (Paralysis Non-reversible)
Phase II (Paralysis Reversible)
Neostigmine (Reversal Agent)
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2 mins
Nonselective Alpha-Blockers
Indications
Phentolamine
Reversible
Pheochromocytoma (Diagnosis)
Hypertensive Crisis
Phenoxybenzamine
Pheochromocytoma (Treatment)
Side Effects
Orthostatic Hypotension
Reflex Tachycardia
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2 mins
Ephedrine
Mechanism of Action
Alpha Agonist
Beta Agonist
Indications
Rhinitis
Hypotension
Urinary Incontinence
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35 secs
Monoamine Oxidase Inhibitors (MAO-Is)
Indications
Atypical Depression
Mechanism of Action
Increase Levels of Amine Neurotransmitters
Drugs
"Takes Pride In Shanghai"
Tranylcypromine
Phenelzine
Isocarboxazid
Selegiline
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1 min
Alpha Agonists
-RINE suffix
Norepinephrine
Hypotension
Phenylephrine
Hypotension
Congestion
Ephedrine
Congestion
Urinary Incontinence
Hypotension
Epinephrine
Anaphylaxis and Asthma
Hypotension
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1 min

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