Daniel Shared "Parm exam 1" - 43 Picmonics
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Parm exam 1
Buspirone (Buspar)
- Mechanism
- Increases Serotonin
- Indications
- Anxiety
- Side Effects
- Dizziness
- Insomnia
- Considerations
- Delayed Effect
- Safer with Alcohol than Other Anxiolytics
- Low Side Effect Profile
- Low Abuse Potential
1 min
Alprazolam (Zanax)
- Indications
- Anxiety
- Pre-procedural sedation
- MOA
- Enhances GABA
- Reduce neuron excitability
- Side Effect
- Decreased Libido
- Anterograde Amnesia
- Confusion / Lethargy
- Urinary Incontinence
- CNS and RR Depression
- Nurse Implications
- Syncope (Fainting)
- Tolerance Develops
- Food Drug Interaction
- PO only
- Bad for Pregnancy
Fluoxetine (Prozac)
- Mechanism of Action
- Inhibits Reuptake of Serotonin
- Indications
- Depression
- Side Effects
- Sexual Dysfunction
- CNS Stimulation
- Weight Changes
- Serotonin Syndrome
- Contraindications
- No MAO-Is
- No Anticoagulants / Antiplatelets
- Considerations
- Suicide Risk
- Delayed Onset of Action
2 mins
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Indications
- Depression
- Anxiety
- Mechanism of Action
- Selective Serotonin Reuptake Inhibitors
- Drugs
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Side Effects
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
2 mins
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Indications
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Mechanism of Action
- Inhibits Reuptake of Serotonin and NE
- Side Effects
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
1 min
Bupropion
- Indications
- Depression
- Smoking Cessation
- Mechanism of Action
- Increase Dopamine and NE
- Side Effects
- Stimulant Side Effects
- Seizure
1 min
Atypical antidepressants
- Bupropion
- Mirtazapine
- trazodone
- vilazodone
Vilazodone
- Mechanisms
- Inhibiting Serotonin Reuptake
- 5HT1A Receptor Partial Agonist
- Use
- Major Depressive Disorder
- Anxiety
- Side Effects
- Anticholinergic Effects
- Headache
- Nausea and Diarrhea
- May cause Serotonin Syndrome
Tricyclic Antidepressants (TCAs) Indications
- Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- Drugs
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
2 mins
Tricyclic Antidepressants (TCAs)
- Mechanism of Action
- Inhibits Reuptake of Norepinephrine and Serotonin
- Indications
- Depression
- Bipolar Disorder
- Fibromyalgia
- Side Effects
- Sedation
- Orthostatic Hypotension
- Anticholinergic Effects
- Cardiac Toxicity
- Considerations
- Delayed Effect
- Do Not Stop Abruptly
2 mins
Mirtazapine and Varenicline (Atypical Antidepressants)
- Mirtazapine
- α2-antagonist (Increased release of NE and 5-HT)
- Potent 5-HT2 and 5-HT3 receptor antagonist and H1 antagonist
- Toxicity: sedation (which may be desirable in depressed patients with insomnia), increased appetite, weight gain (which may be desirable in elderly or anorexic patients), dry mouth
- Varenicline
- Nicotinic ACh receptor partial agonist
- Used for smoking cessation (decreases both cravings and decreasing the rewarding effects of nicotine)
- Toxicity: sleep disturbance
Trazodone
- Indications
- Insomnia
- Depression
- Mechanism of Action
- Inhibit Serotonin Reuptake
- Alpha-1 Blocker
- Histamine (H1) Blocker
- Side Effects
- Sedation
- Orthostatic Hypotension
- Dry Mouth
- Priapism
- Arrhythmias
2 mins
Monoamine Oxidase Inhibitors (MAO-Is)
- Indications
- Atypical Depression
- Mechanism of Action
- Increase Levels of Amine Neurotransmitters
- Drugs
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
1 min
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
- Autonomic Instability
- Muscle Rigidity
- Malignant Hyperthermia
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Dantrolene
- Neuroleptic Malignant Syndrome
- Antidopaminergic Medications
- Hyporeflexia
- Myoglobinuria
- Dantrolene
- Serotonin Syndrome
- Serotonergic Medications
- Hyperreflexia
- Clonus
- Cyproheptadine
3 mins
Lithium
- Mechanism of Action
- Mood Stabilizer
- Unknown Mechanism
- Indications
- Bipolar Disorder
- Side Effects
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Tremor
- Heart Block
- Contraindication
- Pregnancy
- Considerations
- Monitor Plasma Levels
2 mins
Bipolar Disorder Interventions
- Drug Therapy
- Lithium
- Valproic Acid (Valproate)
- Lamotrigine
- Manic Episode
- Hospitalization
- Nutrition
- Hygiene
- Depressive Episode
- Monitor for Vegetative Signs
- Suicide Precautions
2 mins
Carbamazepine (Tegretol)
- Mechanism
- Inactivates Na+ Channels
- Indications
- Seizures
- Bipolar Disorder
- Trigeminal Neuralgia
- Side Effects
- Nystagmus
- Ataxia
- Hepatotoxicity
- Blood Dyscrasias
- Water Retention
- Stevens-Johnson Syndrome
- Considerations
- Avoid Grapefruit Juice
2 mins
Warfarin Antidotes
- Antidotes
- Vitamin K
- Fresh Frozen Plasma
59 secs
Warfarin (Coumadin)
- Mechanism of Action
- Inhibits Clotting Factors
- Indications
- Atrial Fibrillation
- Venous Thrombosis
- Pulmonary Embolism
- Assessment
- PT/INR Levels
- Observe for Bleeding
- Contraindications
- Pregnancy
- Nursing Considerations
- Vitamin K and Fresh Frozen Plasma
- Prolonged Therapeutic Onset
- Maintain Same Diet
2 mins
Lamotrigine (Lamictal)
- Mechanism
- Blocks Na+ Channels
- Indications
- Seizures
- Bipolar Disorder
- Side Effects
- Diplopia
- Stevens-Johnson Syndrome
- Headache
- Aseptic Meningitis
- Nausea and Vomiting
- Considerations
- Screen for Suicide Risk
2 mins
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