Janani Shared "Z Resp" - 7 Picmonics

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Z Resp

Lung development
Embryonic
Wk 4-7
TE fistulas
Pseudoglandular
Wk 5-17
Modest capillary network
Canalicular
Wk 16-26
Respiration possible at 25 weeks
Saccular
26-birth
terminal sacs (primary septation)
Primary septation of alveoli
Alveolar
Wk 36-8yo
adult sacs
Secondary septation of alveoli
pneumocytes develop
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Methemoglobinemia
Methemoglobinemia
Fe3+
chocolate colored blood
Caused by sulfa, nitrate, or benzocaine
Can treat cyanide poisoning
Antidote is methylene blue and vitamin c
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Cyanide Toxicity
Mechanism
Impedes Oxidative Phosphorylation
Lactic Acidosis
Metabolic Acidosis
Symptoms
Skin Flushing
Tachycardia
Tachypnea
Vomiting
Change In LOC (Altered Mental Status)
Seizures
Coma
Treatment
Hydroxocobalamin
Sodium Thiosulphate
Nitrates
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Toxins Affecting the Electron Transport Chain
Complex I
NADH Dehydrogenase
Amobarbital
Rotenone
Complex III
Coenzyme Q Oxidoreductase
Antimycin A
Complex IV
Cytochrome C
Carbon Monoxide
Cyanide
Complex V
ATP Synthase
Oligomycin
Proton Gradient
2,4-Dinitrophenol
Aspirin
Uncoupling Agents
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Winter's Formula
Evaluates Respiratory Compensation
Used in Metabolic Acidosis
Equation
(HCO3 x 1.5 ) + 8 plus-minus 2 = PCO2
Steps
Bicarbonate (HCO3) x 1.5
+ 8
± 2
= Expected Value for PCO2
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1 min
Sarcoidosis Characteristics and Labs
Mechanism
Unknown Mechanism
Immune-mediated
Noncaseating granulomas
Vitamin D activation
Labs
Hypercalcemia
Elevated ACE
Asteroid bodies
X-Ray shows Bilateral hilar lymphadenopathy
Treatment
Corticosteroids
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1 min
Sarcoidosis Symptoms
Black Females
Symptoms
Asymptomatic
Uveitis
Interstitial Fibrosis
Erythema Nodosum
Hepatomegaly
Myocardial Sarcoidosis
Lupus Pernio
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1 min

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