Kourtney Shared "AGACNP 2- Dermatology Conditions" - 20 Picmonics
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AGACNP 2- Dermatology Conditions
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
1 min
Types of Malignant Melanoma
- Superficial Spreading
- Most Common Cause of Melanoma
- Nodular
- Aggressive and Rapidly Arising
- Acral-Lentiginous
- Males
- Asians and African Americans
- Lentigo Maligna
- Geographic Shape
- Sun Exposed Areas
2 mins
Melanoma Mechanism and Characteristics
- Mechanism
- Associated with Sunlight Exposure
- Mutation in B-RAF kinase
- Large Number of Moles
- Fair-Skinned People at Higher Risk
- Growth Phases
- Radial Growth Phase
- No Metastasis
- Vertical Growth Phase
- Depth of Tumor Correlates with Risk of Metastasis
1 min
Melanoma Diagnosis
- Signs
- ABCDE Mnemonic
- Asymmetry
- Border irregularity
- Color variation
- Diameter > 6mm
- Evolution over time
- Diagnosis
- S-100 Tumor Marker
- LDH (Lactate Dehydrogenase) Screens for Metastasis
- Treatment
- Wide Local Excision
- Adjuvant Therapy
1 min
Atopic Dermatitis / Eczema
- Presentation
- Pruritic Vesicles
- Inflammatory Skin Rash
- Cheeks in Children
- Skin Flexural Areas
- Associated with Asthma and Allergic Rhinitis
- Treatment
- Tacrolimus
- Moisturizers
- Corticosteroids
- Phototherapy
- Avoid Triggers
- Antihistamines
2 mins
Psoriasis
- Presentation
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Histological Finding
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Treatment
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
2 mins
Tinea (Dermatophytes): General Characteristics And Management
- Fungal Cutaneous Infection
- Organisms
- Trichophyton
- Microsporum
- Epidermophyton
- Clinical Features
- Pruritic Rash
- Segmented Hyphae On KOH
- Management
- Topical Azole
- Terbinafine For Tinea Unguium (Nails)
2 mins
Pityriasis Versicolor (Tinea versicolor)
- Mechanism
- Lipid-Dependent Fungus
- Fatty Acids Damage Melanocytes
- Malassezia Furfur
- Hot, Humid Weather
- Signs and Symptoms
- Hypopigmentation
- Hyperpigmented Patches
- Diagnosis
- Spaghetti and Meatball Appearance on KOH Prep
- Fragmented Hyphae with Clusters of Yeast
- Treatment
- Topical or Oral Antifungals
- Selenium Sulfide
- Zinc
4 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Nystatin
- Indications
- Candidiasis
- Vaginal
- Oral
- Cutaneous
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
- Topical form of Amphotericin B
- Side Effects
- Rash
1 min
Mycosis Fungoides / Sézary Syndrome
- Mechanism
- Neoplastic CD4+ Cells
- Adults 40 - 60 Years Old
- Mycosis Fungoides
- Neoplastic CD4+ Cells Infiltrate Skin
- Rashes Or Plaques
- Pautrier's Abscesses
- Sézary Syndrome
- Neoplastic CD4+ Spread from Skin to Systemic Involvement
- Sézary Cells With "Cerebriform Nuclei"
2 mins
Herpes Zoster (Shingles)
- Cause/Mechanism
- Varicella-Zoster Virus
- Assessment
- Linear, Unilateral Rash Along a Dermatome
- Pruritus
- Postherpetic Neuralgia
- Interventions
- Acyclovir
- Analgesics
- Gabapentin
- Considerations
- Contagious Vesicles
- Shingrix
3 mins
Herpes Simplex Virus (HSV)
- Characteristics
- Enveloped
- Double Stranded DNA
- Linear
- Signs and Symptoms
- Type 1 HSV
- Gingivostomatitis
- Keratoconjunctivitis
- Encephalitis of Temporal Lobes
- Latent in Trigeminal Ganglia
- Type 2 HSV
- Genital Vesicles
- Neonatal Herpes
- TORCHES
- Latent in Sacral Ganglia
- Diagnosis
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusions
- Treatment
- Acyclovir
2 mins
Genital Herpes
- Mechanism
- Herpes Simplex Virus 1 and 2 (HSV)
- Assessment
- May Be Asymptomatic
- Oral or Genital Lesions
- Vesicles in Clusters
- Pain
- Flu-like Symptoms
- Antiviral Medications
- Acyclovir
- Valacyclovir
- Famciclovir
- Considerations
- Infectious During Recurrences
2 mins
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Cidofovir
- Indications
- CMV Retinitis
- Acyclovir-Resistant HSV
- Mechanism
- Inhibits Viral DNA Polymerase
- Side Effects
- Nephrotoxicity
- Administer with Probenecid and IV Saline
1 min
Hypersensitivity Type IV
- Delayed-Type Hypersensitivity
- T Cell Mediated
- Antibody Independant
- Macrophages Activated
- Examples
- Transplant Rejection
- PPD Skin Test
- Contact Dermatitis
1 min
Acne Vulgaris Presentation and Pathophysiology
- Presentation
- Papules/Comedones in Mild Cases
- Blackheads Open, Whiteheads Closed
- Pustules in Mild-Moderate Cases
- Nodules/Cysts in Severe Cases
- Pathophysiology
- Inflammation at Hair Follicle/Sebaceous Gland
- Increased Androgens
- Colonization by Cutibacterium Acnes
3 mins
Rosacea
- Characteristics
- Episodes Provoked by Alcohol, Heat, or Emotions
- Erythematotelangiectatic Rosacea
- Facial Flushing and Telangiectasias
- Sun Protection
- Topical Brimonidine
- Papulopustular Rosacea
- Papules and Pustules
- Topical Metronidazole
- Phymatous Rosacea
- Rhinophyma
- Laser Ablation
- Considerations
- Avoid Triggers
2 mins
Basal Cell Carcinoma of the Skin
- Pathophysiology
- Most Common Skin Cancer
- 2/3 of Cases Due to UV Light Exposure
- Pink, Pearl-like Lesions
- Rolled Borders
- Telangiectasias
- Commonly Upper Lip
- Diagnosis
- Shave Biopsy
- Pallisading Nuclei
- Treatment
- Mohs Micrographic Surgery
2 mins
