Matthew Shared "ORD Exam 2 - Derm" - 54 Picmonics

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ORD Exam 2 - Derm

Skin Anatomy
Characteristics
Epidermis
Keratinocytes
Melanocytes
Dendritic Cells
Merkel Cells
Dermis
Sweat Glands
Hair Follicles
Sebaceous Glands
Hypodermis
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3 mins
Atopic Dermatitis / Eczema
Presentation
Pruritic Vesicles
Inflammatory Skin Rash
Cheeks in Children
Skin Flexural Areas
Associated with Asthma and Allergic Rhinitis
Treatment
Tacrolimus
Moisturizers
Corticosteroids
Phototherapy
Avoid Triggers
Antihistamines
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2 mins
Psoriasis
Presentation
Epidermal Hyperproliferation Keratinocytes
Defined Red Salmon Plaques
Silvery Scales
Extensor Surfaces
Bleeding when Removed
Auspitz Sign
Pruritus
Nail Changes
Histological Finding
Munro Microabscesses
Nucleated Cells in Stratum Corneum
Treatment
Retinoids
Topical Corticosteroids
Tar
Immunosuppressants
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2 mins
Lichen Planus
Pathophysiology
Mucocutaneous Disorder
30-60 year olds
Signs & Symptoms
Pruritic
Plaques or Papules
Purple & Polygonal
Often Mucosal or Genital Involvement
Wickham Striae
Diagnosis
Biopsy
Sawtooth Infiltrate of Lymphocytes
Treatment
Topical Corticosteroids
Considerations
Hepatitis C Association
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2 mins
Pityriasis Versicolor (Tinea versicolor)
Mechanism
Lipid-Dependent Fungus
Fatty Acids Damage Melanocytes
Malassezia Furfur
Hot, Humid Weather
Signs and Symptoms
Hypopigmentation
Hyperpigmented Patches
Diagnosis
Spaghetti and Meatball Appearance on KOH Prep
Fragmented Hyphae with Clusters of Yeast
Treatment
Topical or Oral Antifungals
Selenium Sulfide
Zinc
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4 mins
Pityriasis Rosea
Preceded by Upper Respiratory Tract Infection
Single "Herald Patch"
"Christmas Tree" Distribution
Plaques with Collarette Scale
Self-resolving in 6-8 Weeks
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1 min
Leishmania donovani
Pathophysiology
Protozoan
Visceral Leishmaniasis
Hepatosplenomegaly
Spiking Fevers
Skin Pigmentation
Sandfly
Diagnosis
Macrophages with Amastigotes
Treatment
Amphotericin B
Oral Miltefosine
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2 mins
Rocky Mountain Spotted Fever
Rickettsia rickettsii
Dermacentor Wood Tick
Endemic to East Coast
Fever
Headache
Rash Starts on Wrist and Ankle
Migrates towards trunk
Thrombocytopenia
Hyponatremia
Elevated liver enzymes
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59 secs
Borrelia burgdorferi
Characteristics
Lyme Disease
Spirochete
Dark-field Microscopy
Giemsa Stain
Silver Stain
White-footed Mouse
Ixodes Tick
Babesia
Anaplasmosis
Signs & Symptoms
Flu-like Symptoms
Erythema Migrans
Bulls Eye Rash
Bilateral Bell's Palsy
Conduction Defects
Arthropathy
Treatments
Doxycycline
Ceftriaxone
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3 mins
Mycobacterium Tuberculosis Characteristics
Characteristics
Mycolic Acid Cell Wall
Acid-fast
Carbolfuchsin Stain Red
Lowenstein-Jensen Agar
Serpentine Cord Factor
Primary TB
Primary TB
Caseating Granuloma
Ghon Focus
Hilar Lymph Nodes
Ghon Complex
Reactivation TB
Reactivation TB
Reactivation in Apex
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3 mins
Mycobacterium leprae
Aerobic
Acid Fast
Likes Cool Temperature
Tuberculoid leprosy
Granulomatous response
Positive Lepromin Skin Test
Dapsone
Rifampin
Lepromatous leprosy
Weak Immune System
Leonine facies
Negative Lepromin Skin Test
Clofazimine
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2 mins
Meningitis Assessment
Assessment
Nausea and Vomiting
Fever
Nuchal Rigidity
Severe Headache
Purpura
Seizures
Photophobia
Infants and Young Children
Opisthotonus Position
High Pitched Cry
Bulging Fontanel
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2 mins
Neisseria Meningitidis
Characteristics
Gram-Negative
Diplococci
Chocolate Agar
Thayer-Martin Media
VPN
Oxidase-Positive
Maltose Fermentation
Glucose Fermentation
Endotoxin
Lipooligosaccharide (LOS) in Membrane
Polysaccharide Capsule
IgA Protease
Disease
Waterhouse Friderichsen Syndrome
Adrenal Insufficiency
Petechial Rash
Treatments
Ceftriaxone
Rifampin Prophylaxis
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5 mins
Bartonella henselae
Characteristics
Gram-Negative
Pleomorphic
Bacillus
Signs and Symptoms
Cat Scratch Fever
Lymphadenopathy
Bacillary Angiomatosis
Patients with AIDS
Mimics Kaposi Sarcoma
Benign
Reactive Arthritis
Non-Caseating Granuloma
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2 mins
Francisella tularensis
Gram-Negative
Coccobacilli
Fever
Lymphadenopathy
Deer Fly
Dermacentor Wood Tick
Rabbit skinning
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1 min
Pemphigus Vulgaris
Pathophysiology
Autoantibodies against desmosomes
Symptoms
Flaccid Bullae on Skin
Oral Mucosa Involvement
Intraepidermal Acantholysis
Fluid Loss
Infection
Nikolsky Positive
Diagnosis
Biopsy showing Autoantibodies
Treatment
IVIG and Plasmapheresis
Oral Steroids
Immunosuppressants
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2 mins
Bullous Pemphigoid
Linear Deposits of IgG
Affects Hemidesmosomes
Epidermal Basement Membrane
Tense Blisters on Skin
Nikolsky Negative
Contain Eosinophils
Rarely Affect Oral Mucosa
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2 mins
Erythema Nodosum
Pathophysiology
Panniculitis
Painful Inflammation
Subcutaneous Fat
Anterior Shins
Risk Factors
Coccidioidomycosis
Pregnancy or OCP Use
Crohn's Disease
Tuberculosis (TB)
Histoplasmosis
Sarcoidosis
Ulcerative Colitis
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2 mins
Erythema Multiforme
Progression
Stevens-Johnson Syndrome
Toxic Epidermal Necrolysis
Associated Infections
Target Lesions
Mycoplasma pneumonia
Herpes Simplex Virus
Drug Reactions are Most Common Cause
Sulfa drug
Beta lactam drugs
Phenytoin
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Stevens-Johnson Syndrome
Etiologies
Drugs
Symptoms
< 10% of Body Surface Area (BSA) Involved
10-30% BSA Overlaps with Toxic Epidermal Necrolysis (TEN)
Fever
Affects Skin and Mucous Membranes
Bullae Formation
Necrosis
Sloughing of Skin
High Mortality Rate
Treatment
Supportive Care
IVIG (Intravenous Immunoglobulin)
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3 mins

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