OnlineMedEd Shared "Infectious Disease - TB" - 5 Picmonics

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Infectious Disease - TB

Mycobacterium Tuberculosis Characteristics
Mycolic Acid Cell Wall
Carbolfuchsin Stain Red
Lowenstein-Jensen Agar
Serpentine Cord Factor
Primary TB
Primary TB
Caseating Granuloma
Ghon Focus
Hilar Lymph Nodes
Ghon Complex
Reactivation TB
Reactivation TB
Reactivation in Apex
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3 mins
Tuberculosis Skin Mantoux Test (PPD)
Delayed Hypersensitivity (Cell Mediated Response)
Intradermal Injection
Read 48-72 hours
Positive Results
≥ 5 mm Induration
≥ 10 mm Induration
High Risk Patients
≥ 15 mm Induration
Chest X-Ray
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3 mins
Tuberculosis (TB)
Blocks RNA Polymerization
Haemophilus influenzae Type B
P450 inducer
Red-orange urine
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55 secs
Tuberculosis (TB)
Mechanism of Action
Requires Catalase Peroxidase
Decreases Mycolic Acid Synthesis
Fast vs Slow Acetylators
Side Effects
B6 Deficiency
Drug-induced Lupus
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1 min
Mechanism of Action
Blocks Arabinosyltransferase
Arabinosyltransferase Polymerizes Carbohydrates
Carbohydrate Polymers Make Mycobacterium TB Cell Wall
Side Effects
Red/Green Color Blindness
Reversible with Drug Discontinuation
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40 secs

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