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Pharm II Exam 1
Cromolyn (Mast Cell Stabilizers)
Mechanism
Mast Cell Stabilizer
Indications
Asthma Prophylaxis
Bronchial Inflammation
Allergic Rhinitis
Side Effects
Cough
Bronchospasm
Consideration
Fixed Schedule Administration
2 mins
Promethazine (Phenergan)
Mechanism
Histamine H1 Receptor Antagonist
Weak Dopamine Antagonist
Indications
Nausea and Vomiting
Motion Sickness
Side Effects
Respiratory Depression
Sedation
Anticholinergic Effects
Extrapyramidal Symptoms
Considerations
Use Large Bore IV
Monitor for Tissue Necrosis
2 mins
Benzodiazepine Antidote
Antidote
Flumazenil
40 secs
Warfarin Antidotes
Antidotes
Vitamin K
Fresh Frozen Plasma
59 secs
Acetylcholinesterase Inhibitor Antidote
Antidote
Atropine
Pralidoxime
1 min
Acetaminophen Antidote
Antidote
N-Acetylcysteine
33 secs
Antimuscarinic Antidote
Antidote
Physostigmine Salicylate
44 secs
Amphetamine Antidote
Antidote
Ammonium Chloride (NH4Cl)
Acidify Urine
34 secs
Beta Blocker Antidote
Antidote
Glucagon
29 secs
Arsenic, Gold and Copper Antidotes
Toxic Metals
Arsenic
Gold
Copper
Antidotes
Penicillamine
Dimercaprol (BAL)
Succimer
2 mins
Iron Antidote
Antidote
DeFEroxamine
23 secs
Opioid Antidote
Antidote
Naloxone
29 secs
Tricyclic Antidepressant (TCA) Antidote
Antidote
Sodium Bicarbonate (NaHCO3)
27 secs
Aspirin Poisoning (Salicylism) Assessment
Early Symptoms
Nausea and Vomiting
Tinnitus
Confusion
Hyperventilation
Respiratory Alkalosis
Late Symptoms
Metabolic Acidosis
Coma
Hyperthermia
1 min
Lead Antidotes
Antidotes
Dimercaprol
CaEDTA
Succimer
39 secs
H2 Receptor Blocker
"-tidine" Suffix
Indications
Gastroesophageal Reflux Disease (GERD)
Peptic Ulcer
Mechanism
Block Histamine H2 Receptors
Parietal Cells
52 secs
H2 Receptor Blocker Side Effects
Side Effects
Decrease Creatinine Clearance
Cimetidine
Crosses Blood-Brain Barrier
Anti-Androgen
Inhibits Cytochrome P450
1 min
Inflammatory Response
Pathogens Infect Tissue
Mast Cells Release Histamine
Histamine Dilates and Increases Capillary Permeability
Macrophages Engulf Pathogens
Macrophage Signals Cells With Cytokines
Responding Neutrophils Cross Capillary Wall
B And T Lymphocytes Arrive At Injury Site
2 mins
1st Generation H1 Blockers
Diphenhydramine (Benadryl)
Doxepin
Hydroxyzine
Promethazine (Phenergan)
Meclizine (Antivert)
Chlorpheniramine
2nd Generation H1 Blockers
Loratadine
Desloratadine
Azelastine
Cetirizine
Fexofenadine
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