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micro Gr -
Neisseria gonorrhoeae Characteristics
Characteristics
Gram Negative
Diplococci
Chocolate Agar
Thayer-Martin Media
VPN
Oxidase Positive
Glucose Fermenting
Pilus
Opa Surface Protein
Rapid Antigenic Variation
IgA Protease
2 mins
Neisseria gonorrhoeae Disease
Signs & Symptoms
Dysuria
Pelvic Inflammatory Disease (PID)
Fitz-Hugh-Curtis Syndrome
Neonatal Conjunctivitis
Pharyngitis
Septic Arthritis
Tenosynovitis
Pustules On Hands And Feet
Treatment
Ceftriaxone
Azithromycin
Doxycycline
Considerations
C5-9 Complement Deficiency (Recurrent Infections)
2 mins
Neisseria Meningitidis
Characteristics
Gram-Negative
Diplococci
Chocolate Agar
Thayer-Martin Media
VPN
Oxidase-Positive
Maltose Fermentation
Glucose Fermentation
Endotoxin
Lipooligosaccharide (LOS) in Membrane
Polysaccharide Capsule
IgA Protease
Disease
Waterhouse Friderichsen Syndrome
Adrenal Insufficiency
Petechial Rash
Treatments
Ceftriaxone
Rifampin Prophylaxis
5 mins
Haemophilus influenzae Characteristics
Characteristics
Gram-Negative
Coccobacilli
PRP Capsule in Type B
Positive Quellung Reaction
IgA Protease
Chocolate Agar
Factor V is NAD
Factor X is Hematin
Staph Aureus Provides Factor V
2 mins
Haemophilus Influenzae Disease
Disease
Pneumonia
Cherry Red Epiglottitis
Meningitis
Otitis Media
COPD Exacerbation
Thumbprint Sign (on X-ray)
Treatment
Rifampin Prophylaxis
Ceftriaxone
2 mins
Bordetella pertussis
Pathophysiology
Gram-Negative
Coccobacillus
Bordet-Gengou Agar
ADP Ribosylating AB Toxin
Inhibits Gi to cause Increase in cAMP
Signs AND Symptoms
Lymphocytosis
Increase in Insulin
Catarrhal Phase is Infectious Period
Paroxysmal Phase is Symptomatic Period
Whooping Cough
Treatment
Macrolides
4 mins
Legionella Characteristics
Characteristics
Bacillus
Poor Gram Stain
Charcoal Yeast with Iron and Cysteine
Silver Stain
Water Sources
Smokers and Heavy Drinkers
Detect Antigen in Urine
2 mins
Legionella Disease
Signs and Symptoms
High Fever
Diarrhea
Increased Liver Enzymes
Hyponatremia
Type IV Renal Tubular Acidosis
Severe Atypical Pneumonia
Pontiac Fever
Treatment
Fluoroquinolones
Macrolides
2 mins
Pseudomonas Aeruginosa Characteristics
Characteristics
Gram-Negative
Bacillus
Aerobic
Pyocyanin Pigment
Blue-green Pigment
Grape like odor
Non-lactose Fermenting
Polysaccharide Capsule
Catalase-Positive
Oxidase-Positive
Inactivates Elongation Factor 2
Exotoxin A
Endotoxin
Water sources
3 mins
Pseudomonas Aeruginosa Disease
Signs and Symptoms
Pneumonia
Cystic Fibrosis
Burn Wounds
Hot tub folliculitis
Urinary Tract Infections
Osteomyelitis associated with IV drug use
Osteomyelitis from Shoe Puncture Wound
Diabetic Osteomyelitis
Corneal Infections in contact lens users
Endocarditis
Ecthyma Gangrenosum
3 mins
E. coli Overview
Characteristics
Gram-Negative
Bacillus
Purple Colony with Metallic Green Sheen
Lactose-Fermenting
Pink on MacConkey Agar
Disease
Diarrhea
Lipid A Septic Shock
P Pili Pyelonephritis and Cystitis
K Capsule Neonatal Meningitis
K Capsule Pneumonia
H Antigen Flagella
2 mins
Enterohemorrhagic E. Coli (EHEC)
Characteristics
O157:H7
Non-Sorbitol Fermenting
Hamburger Meat
Produces Shiga-like Toxin
Gram-negative
Lysogeny
Inactivates 60S Ribosome
Disease
Bloody Diarrhea
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Acute Renal Failure
Thrombocytopenia
2 mins
Klebsiella Characteristics
Characteristics
Gram-Negative
Bacilli
Oxidase-Negative
Intestinal Flora
Antiphagocytic Virulence Factor
Polysaccharide Capsule
Positive Quellung Reaction
Mucoid Colonies
Urease-Positive
Fast Lactose Fermenter
Pink on MacConkey Agar
2 mins
Klebsiella Disease
Signs and Symptoms
Aspiration Pneumonia
Alcoholics
Diabetics
Red Currant Jelly Sputum
Lung Abscess
Nosocomial Urinary Tract Infection
2 mins
Campylobacter jejuni
Characteristics
Gram-Negative
Bacillus
Flagella
Curved
Corkscrew Appearance
Oxidase-Positive
Grows Well at 42 Degrees
Undercooked Meat
Unpasteurized Milk
Animals with Diarrhea
Signs and Symptoms
Bloody Diarrhea
Guillain-Barre syndrome
Reactive Arthritis
3 mins
Salmonella Typhi
Characteristics
Colonizes Gallbladder
Monocytic Immune Response
Symptoms
Typhoid Fever
Abdominal Pain
Rose Spots on Abdomen
Constipation Followed by Diarrhea
Treatments
Ceftriaxone
Fluoroquinolones
Considerations
Oral Vaccine - Live
IM Vaccine - Capsular Polysaccharide
2 mins
Salmonella Enterica Spp.
Characteristics
Animal and Human Reservoir
Poultry and Eggs
Turtles
PMN Immune Response
Symptoms
Gastroenteritis
Diarrhea
Possibly Bloody
Treatments
No Antibiotics
No Vaccine Available
2 mins
Shigella
Characteristics
Gram-Negative
Bacilli
Non Lactose Fermenting
White on Macconkey Agar
Oxidase Negative
Non H2S Producing
Day Care Centers
High Virulence
Replicates Intracellularly
Actin Rocket
Signs and Symptoms
Bloody Diarrhea
Shiga Toxin
Inhibits 60S Ribosome
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Thrombocytopenia
Kidney Failure
3 mins
Vibrio Cholera Characteristics
Gram-Negative
Bacilli
Glucose Fermenting
Non-lactose Fermenting
Oxidase Positive
Comma Shaped
Thrives in Alkaline Environment
Crustaceans
1 min
Vibrio Cholera Disease
ADP Ribosylating AB Toxin
Turn Gs on Causing Increase in cAMP
Secretion of Cl
Blocks Reabsorption of Na
Rice Water Diarrhea
1 min
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