Dzmitry Shared "Block_3_AS" - 26 Picmonics

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Block_3_AS

Pityriasis Rosea
Preceded by Upper Respiratory Tract Infection
Single "Herald Patch"
"Christmas Tree" Distribution
Plaques with Collarette Scale
Self-resolving in 6-8 Weeks
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1 min
Melanoma Mechanism and Characteristics
Mechanism
Associated with Sunlight Exposure
Mutation in B-RAF kinase
Large Number of Moles
Fair-Skinned people at higher risk
Growth Phases
Radial Growth Phase
No Metastasis
Vertical Growth Phase
Depth of tumor correlates with risk of metastasis
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1 min
Melanoma Diagnosis
Signs
ABCDE Mnemonic
Asymmetry
Border irregularity
Color variation
Diameter > 6mm
Evolution over time
Diagnosis
S-100 Tumor Marker
LDH (Lactate Dehydrogenase) Screens for Metastasis
Treatment
Wide Local Excision
Adjuvant Therapy
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1 min
Actinic Keratosis
Sun Exposure
Papules or Plaques
Small, Rough
Erythematous
Precursor to Squamous Cell Carcinoma
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53 secs
Lichen Planus
Pathophysiology
Mucocutaneous Disorder
30-60 year olds
Signs & Symptoms
Pruritic
Plaques or Papules
Purple & Polygonal
Often Mucosal or Genital Involvement
Wickham Striae
Diagnosis
Biopsy
Sawtooth Infiltrate of Lymphocytes
Treatment
Topical Corticosteroids
Considerations
Hepatitis C Association
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2 mins
Erythema Nodosum
Pathophysiology
Panniculitis
Painful Inflammation
Subcutaneous Fat
Anterior Shins
Risk Factors
Coccidioidomycosis
Pregnancy or OCP Use
Crohn's Disease
Tuberculosis (TB)
Histoplasmosis
Sarcoidosis
Ulcerative Colitis
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2 mins
Bullous Pemphigoid
Linear Deposits of IgG
Affects Hemidesmosomes
Epidermal Basement Membrane
Tense Blisters on Skin
Nikolsky Negative
Contain Eosinophils
Rarely Affect Oral Mucosa
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2 mins
Polycystic Ovarian Syndrome (PCOS) Mechanism
Mechanism
Hyperinsulinemia Increases GnRH Pulse Frequency
Large Increase in LH
Small Decrease in FSH
Increased Androgen Production From Theca-Lutein Cells
Decreased Steroid Hormone-Binding-Globulin (SHBG) Causes Increased Free Testosterone
Obese Patients Have Increased Estrogen
Increased Risk of Endometrial Cancer
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2 mins
Polycystic Ovarian Syndrome (PCOS) Symptoms and Diagnosis
Symptoms
Most Common Cause of Infertility in Women
Amenorrhea
Acne
Hirsutism
Obesity
Diagnosis
Enlarged, Cystic Ovaries
LH:FSH Ratio of 3:1
"String of Pearls" on Ultrasound
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1 min
Polycystic Ovarian Syndrome (PCOS) Treatment
Weight Loss
Oral Contraceptives
Clomiphene Citrate
Anti-androgens
Cyclic Progesterone for Endometrial Protection
Metformin
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1 min
Ovarian Cystadenoma
Non-germ cell tumor
Serous
Unilocular
Bilateral
Mucinous
Multilocular
Benign
Most Common
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48 secs
Ovarian Cystadenocarcinoma
Non-germ Cell Tumor
Mucinous
Peritoneal Spread
Serous
Psammoma Bodies
Bilateral
Malignant
Stromal Invasion
CA 125
BRCA-1 and Lynch Syndrome
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1 min
Brenner Tumor
Pathophysiology
Non-germ cell tumor
Transitional epithelium
Benign and unilateral
Coffee bean nuclei
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2 mins
Teratoma
Germ-cell Tumor
Dermoid Cyst
Immature Teratoma
Struma Ovarii
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2 mins
Dysgerminoma
Germ-cell tumor
Most Common Malignant Germ Cell Tumor
Uniform Cells
Fried Egg Cells
hCG
LDH
Seminoma-like
Turner Syndrome
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2 mins
Yolk Sac Tumor
Germ-cell tumor
AFP
Aggressive Malignancy
Yellow, Friable Solid
Schiller-Duval Bodies
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43 secs
Choriocarcinoma
Germ-cell tumor
Trophoblastic tissue
Hematogenous spread to lungs
Malignant
Theca-lutein cysts
Hydatidiform Mole
hCG
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59 secs
Granulosa Cell Tumor
Granulosa Cells
Non-germ cell tumor
Endometrial Carcinoma
Call-Exner bodies
Estrogen producing
Precocious Puberty
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42 secs
Fibromas
Non-germ cell tumor
Meigs Syndrome
Thecoma
Pulling sensation in groin
Spindle-shaped fibroblasts
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44 secs
Krukenberg Tumor
Non-germ Cell Tumor
Lymphatic Spread to Ovaries
Metastasis
GI Malignancy
Mucin-secreting Signet Cell
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34 secs

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