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3- Microbiology
Staphylococcus aureus Characteristics
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Positive
Beta-Hemolytic
Protein A Virulence Factor
Inhibits Phagocytosis
MRSA
Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
Canned Food in Adults
Spores in Honey
Signs and Symptoms
Descending Flaccid Paralysis
Diplopia
Ptosis
Floppy Baby
Constipation
2 mins
Clostridium perfringens
Characteristics
Gram-Positive
Bacillus
Anaerobe
Spore-Forming
Alpha Toxin Lecithinase
Phospholipase
Heat Labile Enterotoxin
Signs and Symptoms
Myonecrosis
Gas Gangrene
Food Poisoning and Diarrhea
Treatment
Hyperbaric O2 Chamber
2 mins
Clostridioides difficile (Clostridium difficile)
Characteristics
Gram-Positive
Bacillus
Anaerobe
Clindamycin and Ampicillin
Toxin A Enterotoxin
Damages Brush Border of Gut
Toxin B Cytotoxin
Damages Cytoskeletal Structure
Signs and Symptoms
Diarrhea
Pseudomembranous Colitis
Toxic Megacolon
Diagnosis
Detect Toxins in Stool
Treatment
Metronidazole
Vancomycin
3 mins
Corynebacterium diphtheriae
Characteristics
Gram-Positive
Bacillus
Exotoxin
ADP Ribosylation of Elongation Factor 2
Beta Prophage
Lysogeny
Tellurite Agar
Chinese Letters
Metachromatic Blue Red Granules
Aniline Stains Deeply Methylene Blue
Signs and Symptoms
Pseudomembranous Pharyngitis
Lymphadenopathy
Myocarditis
Polyneuritis
3 mins
Listeria Monocytogenes Characteristics
Characteristics
Gram Positive
Bacillus
Intracellular
Survives in Cold Temperature
Actin Rocket
Tumbling Motility
Catalase-Positive
Beta-Hemolytic
Only Gram-Positive with Endotoxin-Like Structure
2 mins
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