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Block 3 Path exam 1
Pilocytic Astrocytoma
Occurs Most Commonly in Kids
Posterior Fossa
Cerebellum
Well Circumscribed
GFAP
Rosenthal Fibers
Eosinophilic Corkscrew Fibers
1 min
Ependymoma
Occur in Children
Fourth Ventricle
Hydrocephalus
Perivascular Pseudorosettes
Rod Shaped Blepharoplasts
Cauda Equina in Adults
Poor Prognosis
Neurofibromatosis Type II
2 mins
Glioblastoma Multiforme
Most Common Malignant Primary Brain Tumor
Grade 4 Astrocytoma
Can Cross Corpus Callosum
Butterfly Glioma
Pseudo-palisading Tumor Cells
Areas of Necrosis and Hemorrhage
Stain Astrocytes for Glial Fibrillary Acidic Protein (GFAP)
Grave Prognosis
2 mins
Hemangioblastoma
Most Often Cerebellar
Associated with Von Hippel-Lindau
Retinal Angiomas
Can Produce EPO
Secondary Polycythemia
Foamy Cells
High Vascularity
59 secs
Normal Pressure Hydrocephalus
Mechanism
Elderly
Idiopathic
Decreased Absorption of CSF
Ventricular Enlargement
Symptom Triad
Urinary Incontinence
Ataxia (Gait)
Cognitive Dysfunction
2 mins
Tuberous Sclerosis
Characteristics
Autosomal Dominant
Signs and Symptoms
Hamartomas in CNS and Skin
Phakoma
Subependymal Giant Cell Astrocytoma
Seizures
Intellectual Disability (Mental Retardation)
Adenoma Sebaceum
Shagreen Patch
Ash-leaf Spots
Renal Angiomyolipoma
Cardiac Rhabdomyoma
2 mins
Von Hippel-Lindau Disease
Pathophysiology
Chromosome 3
Presentation
Hemangioblastomas
Medulla, Retina, Cerebellum
Cysts
Kidney, Liver, Pancreas
Develop Bilateral Renal Carcinomas
Pheochromocytomas
2 mins
Sturge Weber Syndrome
Pathophysiology
GNAQ Gene
Signs and Symptoms
Port Wine Stain
Arterial Venous Malformation
Leptomeningeal Angiomas
Intellectual Disability
Seizures
Pheochromocytoma
Glaucoma
Tram-Track Calcifications
3 mins
Spina Bifida Interventions
Surgery
Prone Position
Cover Sac with Moist (Sterile) Dressing
Measure Head Circumference
Bulging Fontanel
Considerations
Other Congenital Malformations Common
Bowel Control
Neurogenic Bladder
2 mins
Oligodendroglioma
Slow growing tumor
Frontal lobe
Chicken Wire Pattern
Fried egg appearance
Calcifications
32 secs
Spina Bifida Assessment
Cause
Congenital Malformation of Vertebrae
Assessment
Dimple With or Without Hair Tuft
Lumbar Sac
Hydrocephalus
Paralysis
Considerations
Identify Type
2 mins
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