Chris Shared "CNS" - 29 Picmonics
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CNS
Krabbe Disease
- Pathophysiology
- Autosomal Recessive
- Galactocerebrosidase Deficiency
- Increased Psychosine
- Signs and Symptoms
- Developmental Delay
- Peripheral Neuropathy
- Optic Atrophy
- Diagnosis
- Globoid Cells
1 min
Glioblastoma Multiforme
- Most Common Malignant Primary Brain Tumor
- Grade 4 Astrocytoma
- Can Cross Corpus Callosum
- Butterfly Glioma
- Pseudo-palisading Tumor Cells
- Areas of Necrosis and Hemorrhage
- Stain Astrocytes for Glial Fibrillary Acidic Protein (GFAP)
- Grave Prognosis
2 mins
Meningioma
- Epidemiology
- Most Common Adult Primary Brain Tumor
- pathology
- Benign
- Originate from Arachnoid Villi
- Dural Attachment
- Parasagittal
- Clinical Manifestations
- Contralateral Leg Weakness
- Seizures
- Diagnosis
- Psammoma Bodies
- Calcifications
- Increased Bone Density
3 mins
Schwannoma
- Characteristics
- Acoustic Schwannoma
- Cranial Nerve VIII
- Cerebellopontine Angle
- S100 Positive
- Bilateral Schwannoma in Neurofibromatosis Type 2
- Tinnitus
- Cranial Nerve V
- Affects Corneal Reflex
2 mins
Oligodendroglioma
- Slow growing tumor
- Frontal lobe
- Chicken Wire Pattern
- Fried egg appearance
- Calcifications
32 secs
Pilocytic Astrocytoma
- Occurs Most Commonly in Kids
- Posterior Fossa
- Cerebellum
- Well Circumscribed
- GFAP
- Rosenthal Fibers
- Eosinophilic Corkscrew Fibers
1 min
Medulloblastoma
- Pathophysiology
- Occurs in Children
- Cerebellum
- Fourth Ventricle
- Diagnosis
- Small Blue Cells
- Lots of Mitotic Figures
- Homer Wright Rosettes
- Signs and Symptoms
- Hydrocephalus
- Ataxia
- Wide-based Gait
- Treatment
- Radiosensitive
2 mins
Ependymoma
- Occur in Children
- Fourth Ventricle
- Hydrocephalus
- Perivascular Pseudorosettes
- Rod Shaped Blepharoplasts
- Cauda Equina in Adults
- Poor Prognosis
- Neurofibromatosis Type II
2 mins
Craniopharyngioma
- Hypopituitarism
- Remnants of Rathke's Pouch
- Tooth-enamel Like Calcification
- Cholesterol Crystals
- Yellow Viscous Fluid
- Headache
- Bitemporal Hemianopsia
1 min
Hemangioblastoma
- Most Often Cerebellar
- Associated with Von Hippel-Lindau
- Retinal Angiomas
- Can Produce EPO
- Secondary Polycythemia
- Foamy Cells
- High Vascularity
59 secs
Pinealoma
- Pathophysiology
- Melatonin
- Superior Colliculi
- Obstructs Cerebral Aqueduct
- Signs and Symptoms
- Obstructive Hydrocephalus
- Vomiting
- Parinaud's Syndrome
- Paralysis of Upward Gaze
- Setting Sun Sign
- Increased Beta-hCG
- Precocious Puberty
2 mins
Prolactinoma
- Pituitary Adenoma
- Galactorrhea
- Prolactin Inhibits Gonadotropin Releasing Hormone
- Impotence
- Amenorrhea
- Bitemporal Hemianopsia
- Treat with Dopamine
2 mins
Closed-Angle Glaucoma
- Primary
- Lens causes pupillary obstruction
- Aqueous humor builds behind iris
- Iris bends forward, obstructing trabecular mesh
- Secondary
- Hypoxia Causes Neovascular Proliferation
- Contraction and obstruction of trabecular mesh
- Chronic disease (Crone)
- Asymptomatic
- Acute Disease
- Eye pain and blindness
- Rock-hard eye
- Headache
- Emergency
- Epinephrine contraindicated
2 mins
Open-Angle Glaucoma
- Humor Has Access to Trabecular Meshwork
- Presentation
- Painless
- African American
- Elderly
- Positive Family History
- Primary Open-Angle Glaucoma
- Most Common Form of Glaucoma
- Unknown Mechanism
- Secondary Open-Angle Glaucoma
- Blocked Trabecular Meshwork (With Open-Angle)
- WBCs
- Red Blood Cells (RBC)
- Retinal Products
2 mins
Multiple Sclerosis Features and Mechanisms
- Features
- More Common in Women
- Presents in 20's and 30's
- Northern Europeans
- Mechanism
- Unknown mechanism, genetic factor
- HLA-DRB1
- Autoimmune Demyelination of CNS
- White Matter of Brain and Spinal Cord
- T Cell Mediated Inflammation
2 mins
Sturge Weber Syndrome
- Pathophysiology
- GNAQ Gene
- Signs and Symptoms
- Port Wine Stain
- Arterial Venous Malformation
- Leptomeningeal Angiomas
- Intellectual Disability
- Seizures
- Pheochromocytoma
- Glaucoma
- Tram-Track Calcifications
3 mins
Kluver-Bucy Syndrome
- Bilateral Amygdala Lesion
- Associated with HSV-1
- Hyperorality
- Hypersexuality
- Disinhibited Behavior
1 min
Neurofibromatosis Type 1
- Pathophysiology
- Autosomal Dominant
- Chromosome 17
- Signs and Symptoms
- Neurofibromas
- Optic Glioma
- Lisch Nodules
- Hamartomas
- Cafe Au Lait Spots
- Scoliosis
- Pheochromocytoma
4 mins
Neurofibromatosis Type 2
- Pathophysiology
- Autosomal-Dominant
- Chromosome 22
- Signs and Symptoms
- Vestibular Schwannoma
- Meningioma
- Ependymoma
- Cafe Au Lait Spots
- Cataracts
2 mins
Tuberous Sclerosis
- Characteristics
- Autosomal Dominant
- Signs and Symptoms
- Hamartomas in CNS and Skin
- Phakoma
- Subependymal Giant Cell Astrocytoma
- Seizures
- Intellectual Disability (Mental Retardation)
- Adenoma Sebaceum
- Shagreen Patch
- Ash-leaf Spots
- Renal Angiomyolipoma
- Cardiac Rhabdomyoma
2 mins
